BrunetLab

We have posted a Research Assistant (LSRP1) position to work on aging and 'rejuvenation' using mouse models!! 🐭

careersearch.stanford.edu/jobs/life-sc...

Apply and join our awesome lab!! (please share) 😎

Life Science Research Professional 1 in School of Medicine, Stanford, California, United States The Brunet lab in the Department of Genetics at Stanford University (https://web.stanford.edu/group/brunet/) is seeking an independent and motivated.....

Interested in the mechanisms of aging and 'rejuvenation'?

Our lab at Stanford has a Research Assistant/Lab manager position open!!

Apply and join our awesome team! 😎 (please share)

careersearch.stanford.edu/jobs/life-sc...

YouTube video by The Dissenter #1211 Coleen Murphy - How We Age: The Science of Longevity

New episode (1211), with Dr. Coleen Murphy (@ctmurphy1.bsky.social). We talk about her book, How We Age: The Science of Longevity. #Biology #Science

YouTube: youtu.be/Fy22JhtHhdU
Podcast: bit.ly/4a1fCh8

We are hiring!! Lab Assistant II position to work with the killifish! 🐟🐟🐟 This is an amazing model to study aging and 'suspended animation'

careersearch.stanford.edu/jobs/lab-ass...

Come and join our fantastic team at Stanford!! 🤩 Please share!

Join us for an awesome Keystone Symposia in Banff, Canada in March 2026! Fantastic line up of speakers at the juncture between immunity and aging!! www.keystonesymposia.org/conferences/...

📣 Deadline extension for #EMBOBrainEpi!

Good news for anyone who did not submit an abstract for the EMBO Workshop 'Brain (epi)genome': the abstract deadline is now 26 January 👉 s.embl.org/brg26-01-bl

Join us to explore how genome and epigenome shape brain cell diversity, function, and disease 🧠

I'm just delighted to announce our new preprint on genome-scale perturb-seq in CD4+ T cells. We learned both general lessons about the power of perturb-seq, and specific lessons about T cell biology.

Led by amazing postdocs Emma Dann and Ronghui Zhu, with my wonderful collaborator Alex Marson.

Protocol for single-nucleus RNA sequencing of adult C. elegans neurons Single-nucleus sequencing, specifically, remains the gold standard for characterizing difficult-to-dissociate cell types, such as neurons in complex b…

We have had a lot of requests for the protocol for single-nucleus RNA-seq of adult C. elegans neurons that our lab developed - I hope that you find this helpful! 🧪 #Celegans www.sciencedirect.com/science/arti...

Cell Type-Specific Hormonal Signaling Configures Hypothalamic Circuits for Parenting Parenting behavior emerges from hormonally sensitive circuits, but how distinct circuit components are affected by, and contribute to, sex and state dependent changes in infant caregiving remains uncl...

New paper alert!!...🤩 Led by @blogeman.bsky.social, we identify how cell type-specific hormonal responses in the hypothalamus tunes parenting behavior in males and females 🐭🧠🍼. Highlights in thread 👇 1/6

www.biorxiv.org/content/10.6...

Remarkable energy at the inaugural @cshlnews.bsky.social conference on Assembloids and complex cell–cell interactions across tissues and systems
A wonderful series of talks so far highlighting advances & discoveries being made with these self-organizing systems and a few common themes are emerging

Our latest collaboration with @jkpritch.bsky.social – led by joint post-doc Mineto Ota – is in @nature.com today: www.nature.com/articles/s41...

I am thrilled to share our latest work led by @zurisullivan.bsky.social in collaboration with @moffittlab.bsky.social ! We find that the brain encodes distinct, pathogen-specific sickness states across behavior, physiology, neural activity, and gene expression 1/6

www.biorxiv.org/content/10.6...

Top left: Schematic derived from WormPaths showing methionine salvage and arginine-derived metabolic pathways. Information regarding gene level and H3K4me3 status from Control, sams-1 or sams-4 animals in basal or heat-shocked conditions is marked in legend. Data is from Godbole and colleagues eLife 2023. Bottom left: Schematic showing connections between SAM and PC synthesis to trafficking of PC to and within the mitochondria. Right: Transmission electron micrograph of normal mitochondria (blue, top) compared to those with low levels of the phospholipid phosphatidylcholine (pink, bottom) from C. elegans intestinal cells, showing collapse of the mitochondrial network and accumulation along the intestinal lumen. Image taken by Dr. Maria Ericsson

S-adenosylmethionine synthases (SAMS) have distinct roles in #StressResponse & #mitochondrial metabolism in #Celegans. @akw-lab.bsky.social &co show that SAMS-1 supports broad metabolic functions (e.g. PC synthesis), while SAMS-4 aids protein transmethylation @plosbiology.org 🧪 plos.io/4rvQvtt

Conference: Neurogenesis from development to adulthood in health and disease The adult brain consists of billions of neurons that show an unimaginable complexity in their structural diversity and functional connectivity allowing for a plethora of brain functions. Notably…

Interested in neural stem cells and neurogenesis throughout lifespan?

Exciting meeting in 2026 in Switzerland!!

neuro-unige.ch/news/csf-mee...

Congratulations Elphège!! 🤩🥂

Here is a copy of last year's Twitter thread explaining our preprint - jump to (21) for the new stuff 👀

Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function

now revised and journal accepted at www.science.org/doi/10.1126/...

🧵👇

Excellent commentary on transgenerational inheritance and the importance of rigor and reproducibility.

Subtitled: when a colleague drags and tries to throw you under the bus because they couldn't follow protocols

@ctmurphy1.bsky.social

Love this Insight by @steeltownworms.bsky.social on a series of @elife.bsky.social papers on what it takes to reproduce a phenomenon of transgenerationally transmitted learned pathogen avoidance in C. elegans. Thank you, Lesley!
elifesciences.org/articles/109...

Cool neurogenesis meeting in the Swiss Alps!!

'Neurogenesis from development to adulthood in health and disease'

To submit an application: asconameeting@unige.ch

Science brings us new miracles every day. Update from a mother whose son was the first patient dosed with Grace Science's gene therapy for NGly1 deficiency (GS-100). Video can be seen on YouTube. #glycotime

www.youtube.com/watch?v=tdNn...

Congratulations Catherine!! Super well deserved!! 🥂🎉

Protein tug-of-war controls pace of synaptic development, sets human brains apart Human-specific duplicates of SRGAP2 prolong cortical development by manipulating SYNGAP, an autism-linked protein that slows synaptic growth.

Nice cover of our work linking SRGAP2/SYNGAP1 synaptic neoteny and ID/ASD with @blibep.bsky.social @benvermaercke.bsky.social @franckp.bsky.social @boninlab.bsky.social @cecilecharrier.bsky.social www.thetransmitter.org/spectrum/pro...

Thank you Alzforum for featuring our new preprint identifying regulators of disease states of #microglia.

Project led by Amanda McQuade, computation by Reet Mishra, collaboration with the Nunez and De Jager labs.

Alzforum
www.alzforum.org/news/researc...

Preprint
www.biorxiv.org/content/10.1...

For obvious reasons, I've become fascinated with retrotransposons. So we ( @alexwhiteley.bsky.social and I) wrote an article now out in Neuron @cellpress.bsky.social on how we think retrotransposons influence brain function and health! kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...

During these uncertain times, I’m very happy to see that my institution, @scripps.edu has an open tenure-track Assistant Professor position. Any field in Chemistry or Biology is welcome. I’d especially love to see fellow neuroscientists apply. Please repost!

apply.interfolio.com/174756

Poster with QR code linking to the position

I'm very excited to announce that UNC Biology has 6 faculty positions open this year! The first is for an Asst Professor who studies organismal resilience using an integrative approach 1/n
unc.peopleadmin.com/postings/307...

✨ It's happening again! 🚀 Registration for Stem Cells in Neuroscience 2026 has officially opened! 🧠 Don't miss your chance to attend this exciting event with great keynote speakers, thought-provoking workshops and ample networking opportunities 👉🏼 www.stemcelltuebingen.com #neuroscience #stemcells

It should be great!

Interesting in aging, immune function, and organ health?

Join us for a super exciting joint Keystone Symposia in Banff, Canada in March 2026!!

@ericverdin.bsky.social

🎉 Congratulations to Needhi Bhalla, UC Santa Cruz (www.bhallalab.com
), named a 2025 #ASCB Fellow! This honor celebrates her outstanding contributions to cell biology, leadership, & service. Fellows will be recognized at #CellBio2025 in Philadelphia this December. #CellBiology