Anna Roberts

4th day highlights from #SSIB 2025!

A big congratulations to @nataliefigueredob.bsky.social 🥳

These findings suggest a mechanism by which dietary olive oil regulates blood glucose levels and present a novel functional role for enteropancreatic neurons in regulating glucose homeostasis!

Here, we show that olive oil improves acute glucose tolerance by stimulating insulin release via NTSR1-expressing enteropancreatic neurons

Diets rich in olive oil promote weight loss and improve remission rates in patients with T2DM

Enteropancreatic neurons project from the small intestinal wall to the pancreas. Though well positioned to mediate the effects of ingested nutrients, the metabolic role of these neurons is unclear

Excited to share a new preprint from work I did during my PhD! 🎉

Here we uncover a direct gut-pancreas neuronal circuit that drives the glucoregulatory response to lipids 🫒

Huge thanks to @imperialcollegeldn.bsky.social and all involved.

Read it here 📄:
www.biorxiv.org/content/10.1...

GIPR agonism and antagonism decrease body weight and food intake via different mechanisms in male mice - Nature Metabolism This study, together with a companion manuscript, show that, in mice, weight loss as a result of GIP receptor antagonism requires, and potentiates, functional GLP-1 receptor signalling in the brain, e...

It's a big week for GIPR pharmacology! Two great studies out in @natmetabolism.nature.com from Gutgesell et al (www.nature.com/articles/s42...) and Liu et al (www.nature.com/articles/s42...) revealing divergent neural mechanisms engaged by GIPR agonism vs antagonism. Commentary here: rdcu.be/ejPSA

📣Join the Trapp lab as a Postdoctoral Research Fellow!

The Trapp lab is seeking for a highly motivated Research Fellow to explore the role of GLP-1 action within the brain. If you are interested we encourage you to apply!

📍 Location: UCL, London
📆 Application deadline: March 19th

GLP-1 and the Neurobiology of Eating Control: Recent Advances Abstract. Obesity is now considered a chronic relapsing progressive disease, associated with increased all-cause mortality that scales with body weight, af

Really proud to start the year by sharing our new review in @endosocjournals.bsky.social on the roles of GLP-1 in eating and obesity treatment, led by superstar postdoc @laurenjonesucl.bsky.social!

academic.oup.com/endo/article...

🧪🧠📈 #neuroscience #neuroskyence #GLP-1 #obesity #wegovy #ozempic

📣 We are excited to launch this year’s CCMN Lecture Series with Dr. @zknight.bsky.social! Join us to learn about his latest work on:
In vivo imaging of brainstem neurons in response to nutrient intake.

🗓️ Wednesday, Dec 4, 2024
🕐 13:00
📍 H O Schild Lecture Theatre, Medical Sciences Building