Alex Meraz

Maybe because not all attendees are expert nephrologists? Lots of students, residentes, nurses attending as well.

And it’s live

Iptacopan in C3GN makes it to @thelancet.com

www.thelancet.com/journals/lan...

#NephSky

Awesome congrats!!! Is this limited to losartan or it would be more a class effect of ARBs?

Amazing to me that a seemingly acute event is either
A) has long-term sequellae despite being apparently resolving or
B) a dramatic and early presentation of profound endothelial disease

Amazing reference

Way scarier story. Stories.

www.nytimes.com/2025/06/13/t...
(Gift link)

Sibeprenlimab in IgA Nephropathy #ERA25
* Data presented is the 9-month reduction in proteinuria

Dr Meghan Sise presenting on serum cr/cystatin outcomes in patients treated with cisplatin or carboplatin

#Onconeph #ERA25

Shite!

Adverse effects

Hyperkalemia rates not lower with adding a flozin to the MRA 🤔

www.nejm.org/doi/full/10....

#ERA25

Urinary Albumin-to-Creatinine Ratio, Serum Potassium Level, Estimated Glomerular Filtration Rate, and Systolic Blood Pressure over Time.

The first #ERA25 simultaneous pub

CONFIDENCE trial of empagliflozin + finerenone in N = 579

Greater reduction in ACR and BP
Note the impressive GFR dip

www.nejm.org/doi/full/10....

A graph of the least-squares mean ratio of the change from baseline in the urinary albumin-to-creatinine ratio in the full analysis population.

In the CONFIDENCE trial in persons with chronic kidney disease and type 2 diabetes, combination therapy with finerenone and empagliflozin led to a greater reduction in the urinary albumin-to-creatinine ratio than either drug alone. Full trial results: nej.md/4jEVbbk

#ERA25 #MedSky #Nephrology

Missed it. Give us the highlights! #ERA25

@kevinyau.bsky.social GLP1 agonist master Jedi presenting at #ERA25.

💉GLP1 agonist reduce ED visits and hospitalizations!!!

📉Awesome methods. Best of the session:

💊DDP4 for comparison, IPTW, ICES data. Ticking all the right boxes (EPI nerd).

💊Only 40% on SGLT2i!!! We should flozinate more!!!

@kevinyau.bsky.social @armelleid.bsky.social

I wish we had any of the new treatments in Canada. Any.

#ERA25 baby!!!

Visual abstract

Experiential Evidence of Systemic Racism for Indigenous Peoples Navigating Transplantation in Canada - in @kireports.bsky.social

www.kireports.org/article/S246...

#NephSky

Could High Be Better Than Low? Targeting Phosphate in Trials Phosphate is bad, right? As kidney function declines, phosphate excretion goes down. Serum phosphate levels rise, causing parathyroid hormone (PTH) to increase and bring phosphate down. Phosphate h…

The US spends billions of dollars on binders every year

We are doing the RCT to get you the answer - more than 3000 enrolled

ajkdblog.org/2021/06/16/c... and www.nephjc.com/news/2021/2/...

I am not going. But see you in Vienna!!!!

I feel you pain bro.

Read the same in Brener’s book long time ago

Visual abstract for "Mechanistic Differences between Torsemide and Furosemide."

Torsemide is proposed to have clinically important pharmacokinetic and pharmacodynamic advantages over furosemide. This study found no meaningful pharmacokinetic/pharmacodynamic advantages for torsemide versus furosemide. bit.ly/JASN0481

Dapagliflozin improves diabetic kidney disease by inhibiting ferroptosis through β-hydroxybutyrate production Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease. Sodium-glucose cotransporter protein 2 inhibitors (SGLT2i) are antihyperglycemic agents that provide additional renal-...

Dapagliflozin improves diabetic kidney disease by inhibiting ferroptosis through β-hydroxybutyrate production

#Nephrology #endocrinology #Diabetes #SGLT2i #NephSky

www.tandfonline.com/doi/full/10....

D obviously

Case report:
Daratumumab for Bortezomib-Refractory Proliferative Glomerulonephritis With Monoclonal Immunoglobulin Deposits in Kidney Allograft: A Case Report

https://buff.ly/3P5dsSc

Feliz Navidad!

💡 Kidney stone patients not meeting their fluid intake goals? Try this one weird trick!

Sprinkle a little Carolina reaper powder on their food a couple times a day and 💦🆙 they'll be drinking so much water you'll be looking up the latest #NephJC on hyponatremia correction rates! GI docs hate him!

So high BP causes CKD?

Cumulative Blood Pressure Load and Incident CKD

https://bit.ly/4eEtmx7 #OpenAccess

#VisualAbstract