Alex Fellows

Excited to share our latest work with @simonbullock11.bsky.social! We looked at how diverse mRNAs get selected for subcellular localization and it turns out that a single protein can recognize different RNA elements using shared features that weren’t apparent before.
www.biorxiv.org/content/10.1...

Our latest work, in collaboration with the terrific @kashishsingh.bsky.social in the Carter lab @mrclmb.bsky.social is out. So proud of this study and everyone involved...

YouTube video by MRC Laboratory of Molecular Biology Structure Prediction and Design using AlphaFold – Sami Chaaban

Great talk by @sami-c.bsky.social about the proper use and caveats of AlphaFold2/3 predictions, highly recommended to watch www.youtube.com/watch?v=z7vy...

Full lineup now announced for the 2026 #JCSimaging! Everything from #cryo #CLEM #superresolution #ExM #tissueimaging and more! Save the date and spread the word!

Really, really amazing conference. We went last year and the scientific programme and atmosphere were incredible! I 100% recommend attending + submitting an abstract for a talk - spread the word! 🧠

Neurobiologists 🧠!! If you want to give a talk at NeurobioUK this year, the deadline is the 1st August. Don't miss your chance to be part of an absolutely awesome meeting.

An image montage advertising NeuroBioUK - 12th of September 2025 in York. The image is York cathedral superimposed over a fluorescent cortex mouse section coloured to look a bit like a dawn sky.

Registration is now open for NeuroBioUK 2025!
This year we're looking forward to hearing from our plenary speaker @cathyabbott.bsky.social. As ever, all other talks chosen from submitted abstracts so get submitting - we can't wait to see you there!

neurobiouk.sites.sheffield.ac.uk/registration

Very excited to share our latest preprint! We looked at loss and gain of function, innervation, reinnervation, and in vivo axonal transport in a FUS-ALS mouse model!

www.biorxiv.org/content/10.1...

@uclqsion.bsky.social @beccasimkin.bsky.social @andrewtosolini.bsky.social @frattalab.bsky.social

We’ve been quietly working on something BIG… Launching June 16th! 🎉 If you’re a father in STEMM (or know one) who wants to make change & promote caregiving inclusion in the workplace, get in touch!
#FathersWhoCare #StrongEnoughToCare #AcademicDads

Registration is open for the third #NeuroBioUK!! @dozenoaks.bsky.social @alexfellows1.bsky.social and I are excited to see you again in York!

Journal of Cell Science Meeting 2026 Imaging Cell Dynamics Date: 11 – 14 May 2026 Venue: Montanyà Hotel, Catalonia, Spain Register your interest

After the success of our 2023 Imaging Cell Dynamics conference, we’ll be hosting a second #JCSImaging meeting in 2026, organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social‬, @drmichaelway.bsky.social‬ & Giulia Zanetti.
To register your interest: www.biologists.com/meetings/jcs...

This year's poster winners with the Microtubule meeting organizers. Well done to all poster presenters for showcasing some great science!

Great to see our story on dynein & kinesin co-dependence published www.nature.com/articles/s41..., and absolutely chuffed that it's made the front cover (thanks NSMB!). A brilliant News & Views too by Steven Markus www.nature.com/articles/s41.... Collab between @carter-lab.bsky.social & Straube lab🔬

We are happy to announce that @biologists.bsky.social will sponsor the first UK Zebrafish Meeting @lsiexeter.bsky.social. Are you a PhD student/ECR who wants to present your work? Talk or poster? 👍 Deadline for the early bird registration is 15/5/. So, be quick! www.exeter.ac.uk/research/ins....

The Microtubule meeting program is out and is looking great this year again! biology.ed.ac.uk/microtubule/...

Join Adam's Lab! He is an amazing scientist and the project is so cool!

Molecular mechanism for cargo-mediated initiation of kinesin-1 activation Kinesin-1 is a dynamic heterotetrameric assembly of two heavy and two light chains (KHC and KLC) that mediates microtubule-based intracellular transport of many different cargoes. The complex adopts a...

New preprint on kinesin inhibition and activation - collaborative effort across Bristol Biochem and Chemistry with Woolfson and Schaffizel labs and JJ Phillips in Exeter 1/2 www.biorxiv.org/content/10.1...

If this resonates with you, there are always plenty of ECR slots available for NeuroBioUK. Make sure you join the email list neurobiouk.sites.sheffield.ac.uk/contact

Come and check out our stand at #biologists100 with a chance to enter our mystery prize draw!

@biologists.bsky.social @emilyxlucas.bsky.social @harrietasmith.bsky.social

A beginners guide to scientific conferences!

Perfect timing since our entire lab is off to either @bscb-official.bsky.social @biologists.bsky.social #biologists100 in Liverpool or @physicsoflifeuk.bsky.social 2025 in Harrogate next week

An image montage advertising NeuroBioUK - 12th of September 2025 in York. The image is York cathedral superimposed over a fluorescent cortex mouse section coloured to look a bit like a dawn sky.

Do you need some science joy in your life? Do you like neurons? Maybe glia? Molecules? Cell biology? Save the date for #NeuroBioUK25 - the venue is booked and we are excited to see you and your incredible science there on the 12th of September!

neurobiouk.sites.sheffield.ac.uk

Save the date: 16th–17th September 2025

Inaugural meeting for the UK Stem Cell Network
University Place, Manchester

Website and registration link to follow – watch this space!

Last chance to enter our science writing competition and win a cash prize and have your work published in our magazine!

Are you a budding science writer? ✍️

Then enter our science writing competition. Entries can be fiction or non-fiction. Find out more here:

bscb.org/competitions...

Deadline 1st March

Asgard archaea reveal the conserved principles of ESCRT-III membrane remodeling Asgard archaea have two ESCRT-III subunits with the conserved traits that drive stepwise membrane remodeling in eukaryotes.

Happy to share our paper’s final version on the evolution, structure, and membrane binding / remodeling of Asgard ESCRT-III proteins! And my first 🦋 post! www.science.org/doi/10.1126/...

Lara Krüger, stood in the LMB atrium, smiling.

Congratulations to @lara-kruger.bsky.social, postdoc in @deriverylab.bsky.social in @cellbiol-mrclmb.bsky.social, who is leaving the LMB to establish her own research group at @institutcurie.bsky.social in Paris!
Best of luck to you Lara!
#LMBAlumni

Check it out, is finally out!!

Elongator is a microtubule polymerase selective for polyglutamylated tubulin | The EMBO Journal imageimageElongator, an established tRNA-modifying complex, can also stabilize microtubules during asymmetric cell division. This study shows that Elongator subcomplexes achieve this by binding to microtubule ends as well as tubulin dimers, and ...

Elongator is a microtubule polymerase selective for polyglutamylated tubulin | The EMBO Journal www.embopress.org/doi/full/10....

How does tRNA-modifier #Elongator stabilize microtubules during asymmetric cell division?
Vicente Planelles Herrero @deriverylab.bsky.social et al find subcomplexes binding to microtubule ends & tubulin dimers, & enriching microtubules with polyglutamylated tubulin
www.embopress.org/doi/full/10....

Our paper on nurturing a #PositiveResearchCulture within your #research #team published by @wellcometrust.bsky.social gives useful tips for your lab. As well as making you a good team leader, nurturing culture pays off in building your science: 1/11

wellcomeopenresearch.org/articles/9-3...