christine.py

I want a robust and fulfilling social life but I don’t want to text people back, will the horrors never cease

I'm not trying to be an asshole, but I thought the whole appeal of Bluesky was that it was kind of a walled garden. Retirement home for elder millennials, queer den of iniquity, a place to undo the sins of Twitter, etc. etc. Convincing Steak-n-Shake to open up an account here seems beside the point.

In my first year, I heard something similar from a fellow grad student (Latinx/1st Gen/nontrad) who'd once been conscripted into washing and autoclaving everyone's labware:

Even your most well-meaning colleagues are at ease when you assume the role they expect of you. Make them uncomfortable!

Absolutely, but that speaks to training, pipeline, and/or hiring practices. Different issue.

When women-- SWEs, in your case-- are expected to handle all administrative and caretaking tasks *in addition to* their paid role, therein lies the problem.

#OtD 26 May 1970 Black auto worker Gary Thompson was killed at the Eldon Chrysler plant in Detroit due to inadequate safety. Workers went on wildcat strike the next day, partly organised by the League of Revolutionary Black Workers workingclasshistory.com/podcast/e61-...

Bluesky’s two favourite topics are the New York Times and Bluesky.

Looking for mini versions as we speak!

Mexico suits you!

The drip is unreal

Going to attempt to intention-set before I go to bed tonight: the fascism will still be here tomorrow. Rest, then get up and do the work. Deep breath. Tomorrow is another day and another chance to try.

Good night folks.

What do the vaccine preventable diseases look like? A tour of the diseases that are either coming back or at risk of coming back

Because we are “Making America Healthy Again” with an apparent assault on science, vaccines, and healthcare by DJT and RFK JR, here is a quick update of what common vaccine preventable diseases look like.

open.substack.com/pub/drrubin/...

Chinese think tank analyst Victor Gao, in an interview with Channel 4 News, said that China is fully prepared to fight to the very end "because the world is big enough that the United States is not the totality of the market in the world."

Roll for Climate Initiative: A Dungeon Master’s Guide to Running for Local Public Office Hello Friends, do you like Dungeons and Dragons? What’s your favorite class and why is it Circle of Spores Druid? In the campaign I run for my family, my daughter was sent to rescue the mayor…

Hey nerds-
Roll for Climate Initiative: A Dungeon Master’s Guide to Running for Local Public Office
www.southernfriedscience.com/roll-for-cli... by @drandrewthaler.bsky.social

I don’t support all communists; some of you marxists are very dumb

Image of white desk with navy blue desk mat. Pointed towards the top left corner is a metallic orange computer mouse with "myAir.0" logo emblazoned on the bottom. Pointed towards the bottom left corner is a multicolored (orange, pink, purple) Apple stylus.

My origami mouse arrived lol. I shouldn't be so excited about something for work, but here I am 🫣🤓

A picture of a sticker saying fuck ICE no human is illegal.

Friendly service announcement that it was recently revealed ICE has been doing surveillance on a variety of social media apps INCLUDING blsky.

Sure would be a shame if people on this site started flooding keywords like "ice" "immigration" "border" & "illegal" with nice little messages like this:

Just found out @markazali.com is here via an unhinged Conner O'Malley set. Welcome to the skyline!

If you also have thoughts about techno-authoritarianism, or techno, or art give him a follow!

The fact congressional Democrats have not hired three dozen D&D rules lawyers with oppositional defiant disorder and turned them loose on parliamentary procedure with the goal of maximum obstruction is such a fucking missed opportunity

see, this plane got measles and was perfectly fine

My point is:

It won’t be them that saves you.

It will be you that saves you.

So get to work.

Because nobody bothered to read it, the new DoD and DoJ actually submitted evidence that opposed their own arguments for a proposed trans military ban. This thread is delightful:

I no longer think in terms of success or failure. Everything is an experiment. It all builds towards something. Nothing is wasted. I can be decisive and take full advantage of opportunities.

The fundamental condition to allow this is safety. Same applies to organisations too.

there is no such thing as a philanthropic billionaire

FBXO31-mediated ubiquitination of OGT maintains O-GlcNAcylation homeostasis to restrain endometrial malignancy | Nature Communications Protein O-GlcNAcylation is a post-translational modification coupled to cellular metabolic plasticity. Aberrant O-GlcNAcylation has been observed in many cancers including endometrial cancer (EC), a common malignancy in women. However, clinical characterization of dysregulated O-GlcNAcylation homeostasis in EC and interrogating its molecular mechanism remain incomplete. Here we report that O-GlcNAcylation level is positively correlated with EC histologic grade in a Chinese cohort containing 219 tumors, validated in The Cancer Genome Atlas dataset. Increasing O-GlcNAcylation in patient-derived endometrial epithelial organoids promotes proliferation and stem-like cell properties, whereas decreasing O-GlcNAcylation limits the growth of endometrial cancer organoids. CRISPR screen and biochemical characterization reveal that tumor suppressor F-box only protein 31 (FBXO31) regulates O-GlcNAcylation homeostasis in EC by ubiquitinating the O-GlcNAc transferase OGT. Downregulation of O-GlcNAcyl

FBXO31 ubiquitinates OGT, regulating O-GlcNAcylation and restraining endometrial cancer. In 219 patients, higher O-GlcNAcylation levels link to histologic grade. #CancerResearch PMID:39894887, Nat Commun 2025, @NatureComms https://doi.org/10.1038/s41467-025-56633-z #Medsky #Pharmsky #RNAsky 🧪

Making mifepristone and misoprostol controlled substances not only limits access to these safe medications - it subjects patients to tracking via PDMPs and essentially skirts HIPAA protections. This can be used to criminalize patients AND prescribers.
#medsky #pharmsky

This was the best season of Star Trek

Considering the first MD case was IDed at a Hopkins site in Howard County, makes sense? Like your HCPs could easily have been exposed.

It’s hard to reconcile the “they’ll go after ideologies they don’t like next” talk with the fact they’ve been openly targeting a whole suite of them associated with Black scholarship already. They’ve already threatened to defund any university teaching critical race theory. Why doesn’t that count?