Alessandro Bartolomucci Lab

Remider!
Applications for the McEwen Career Development fellowship in Social Determinants of Health supported by the NIA-BSR High Priority Research Network animalsocialaging-network.org are now open!

apply here animalsocialaging-network.org/funding/fell...

Fellowships | Animal Models for the Social Dimensions of Health and Aging Research Network

📢Applications for the McEwen fellowship are now open!

We expect to award 1-3 fellowships (up to $6,000 each) to early-career scientists with a proposal within the broad scope of our research network’s interests.

Deadline: July 15

Apply here: www.animalsocialaging-network.org/funding/fell...

Reminder - funding opportunity available trough the @animalsocaging.bsky.social

Pilot & Feasibility Awards
Application period - June 1 to June 30

B. McEwen Career Development Fellowship
Application period - June 15 to July 15

Small/Working Group Awards
Application period - July 1 to July 31

📣 @animalsocaging.bsky.social NIA-funded high priority research network - funding available soon!📣

Stay tuned for 3 RFAs:
1. Pilot awards - June 30th
2. The Bruce McEwen Fellowship - July 15
3. Small/working group - July 31

More info on the network: www.animalsocialaging-network.org

Epigenetic biomarkers of mortality risk in mice under chronic social… | Alessandro Bartolomucci New Study: “Epigenetic biomarkers of mortality risk in mice under chronic social stress,” just published in GeroScience. https://lnkd.in/dqPGrQx4 Our study used a large cohort of mice (350+) exposed...

New Study alert: “Epigenetic biomarkers of mortality risk in mice under chronic social stress" @geroscience.bsky.social

lnkd.in/dqPGrQx4

Mathematical models identified epigenetic biomarkers of mortality risk and an association with blood glucose levels, informing on individual aging trajectories.

A graphic describing the details related to applying for the Pilot awards of the Animal Models Social Aging network. Visit animalsocialaging-network.org for details.

📢Applications are OPEN for our Pilot awards!

Individual or mentored projects available with up to $20,000 in total costs! Read the full RFA and apply at the link below!

www.animalsocialaging-network.org/funding/pilo...

@smacklab.bsky.social @bartolomuccilab.bsky.social @jennytung.bsky.social

Ecological Realism Accelerates Epigenetic Aging in Mice Living environment shapes mammalian aging, but laboratory conditions lack the ecological realism of natural social, physical, and microbial environments. Comparing traditionally laboratory-reared and...

New Research Network publication alert!

@sheehanmj.bsky.social and @matthewzipple.bsky.social, both recipients of Network Pilot & Feasibility awards, have published a paper in Aging Cell on ecological realism and epigenetic aging in mice. Congratulations, Mike and Matthew! doi.org/10.1111/acel...

📣 @animalsocaging.bsky.social NIA-funded high priority research network - funding available soon!📣

Stay tuned for 3 RFAs:
1. Pilot awards - June 30th
2. The Bruce McEwen Fellowship - July 15
3. Small/working group - July 31

More info on the network: www.animalsocialaging-network.org

📣New network funding available soon!📣

The Request for Applications for our Research Network's pilot awards (June 1-June 30), the Bruce McEwen Fellowship (June 15-July 15), and small/working group awards (July 1-July 31) will be live on our website (www.animalsocialaging-network.org) in two weeks!

That`s a big one!
congrats to the outstanding team of co-authors

Our NIA funded High Priority Research network on Animal Models for the Social Dimension of Health and Aging just landed on Bsky @animalsocaging.bsky.social
- follow us for updates and new RFAs

www.animalsocialaging-network.org

@smacklab.bsky.social @jennytung.bsky.social

🎤Hey, is this thing on?

The Animal Models for the Social Dimensions of Health and Aging Research Network is on Bluesky! We are an NIA-funded network headquartered at UMN, ASU, UNC, and Duke that supports early-career scientists using animal models to study social aging. New funding available soon!

🚨 Great opportunity for an excellent post doc with a fantastic international group of top notch scholars.

Read here our original article showing the biological age prediction by accumulating stochastic variation alone. With @meyer.bsky.social and a wonderful cover art designed by @maayanvisuals.bsky.social www.nature.com/articles/s43...

Post on the study by the first author @claudiagil93.bsky.social

bsky.app/profile/clau...

Scarce and unpredictable, yet obesogenic: modeling the impact of food insecurity on adiposity in mice Click on the article title to read more.

Food insecurity drives obesity and adiposity, but how is unclear.
A recent study by @clemmensenc.bsky.social developed a mouse model for this phenomenon lnkd.in/d8pEp2qv
Happy to share a commentary written with @johnspeakman4.bsky.social with our take on that study
doi.org/10.1002/oby....

A woman riding a bicycle in Stockholm, Sweden, on September 14, 2018.

The gap in life expectancy between the richest and poorest Swedes widened between 1960–2021. The cause of this trend was not increased inequality or a decline in social spending but an embrace of healthy lifestyles by the affluent. In PNAS: www.pnas.org/doi/10.1073/...

bad news for freshwater quality in minnesota and midwest, very bad in the Twin Cities.

🧠💥 For #Dopamine (DA) & #Memory lovers!

📢 New paper!! we show that memory capacity (MC) in mice can be expanded from 6 to 8 objects using low doses of a D1 receptor agonist. Higher doses? Paradoxically, they reduce MC.

#Tigem
#Consiglio Nazionale delle Ricerche

lnkd.in/d9skfGeb

We recently published
@geroscience.bsky.social
the development and validation of the mouse social frailty index (mSFI) link.springer.com/article/10.1...

We now report a detailed step-by-step resource paper describing how to conduct the mSFI.
bio-protocol.org/en/bpdetail?...

Food insecurity promotes adiposity in mice Objective The obesity epidemic, driven by a complex interplay of environmental and biological factors, remains a significant global health challenge. Herein, we investigate the impact of food insecu...

🌟 Exciting News! 🌟
I am thrilled to share that my first paper as the first author, Food insecurity promotes adiposity in mice, is now published in #ObesityJournal #ObesitySociety

doi.org/10.1002/oby....

#Foodinsecurity #Obesity #PhD

1/9🧵👇

Proud to share the work of my forst ever PhD student and first author of this paper @dylanduerre.bsky.social!! Here, he summarizes it perfectly! #brownfat #metabolism #BCAA #heme @uwmadison.bsky.social @uofutahcihd.bsky.social

Aging activates escape of the silent X chromosome in the female mouse hippocampus Aging activates the silent X chromosome, increasing escape expression, and potentially cognitive resilience, in the female mouse.

"We could all use a little more X!" Thrilled our new study is out. Aging "wakes up" the silent X chromosome in the female brain - and this contributes cognitive resilience. Spearheaded by @margaretgadek.bsky.social in Science Advances. www.science.org/doi/10.1126/...

Exclusive: NIH to terminate hundreds of active research grants Studies that touch on LGBT+ health, gender identity and DEI in the biomedical workforce could be terminated, according to documents obtained by Nature.

In an unprecedented move, the US National Institutes of Health (NIH) has begun mass terminations of research grants that fund active scientific projects because they no longer meet “agency priorities”….

🧪 #AcademicSky

www.nature.com/articles/d41...

Why women’s brains are more resilient: it could be their ‘silent’ X chromosome Study in mice and human cadavers hints that a brain-protective gene in the chromosome becomes more active with age.

Women tend to live longer than men and are often more resilient to cognitive decline as they age.

Now researchers might have uncovered a source for this resilience: the second X chromosome in female cells that was previously considered ‘silent’

https://go.nature.com/3F40x10

Outdoor heat in older adults and accelerated biological (epigenetic) aging
www.science.org/doi/10.1126/...

The Emergence of Protein Organ Clocks Predicting and Tracking Organ-Specific Aging, Health and Disease

This is how you can predict an individual's risk of an age-related disease 2 decades ahead of their showing up. More on this erictopol.substack.com/p/the-emerge...

Protein organ clocks, as assessed in over 6,000 people (~4,000 plasma proteins, 8 organs) with 20-year follow-up are predictive for over 30 age-related diseases
www.thelancet.com/journals/lan...

Really awesome work here 👇🏼👇🏼👇🏼

congrats @scottrussophd.bsky.social wonderful work!