Today in the journal Science: BioEmu from Microsoft Research AI for Science. This generative deep learning method emulates protein equilibrium ensembles β key for understanding protein function at scale. www.science.org/doi/10.1126/...
10.07.2025 18:10 β π 106 π 49 π¬ 1 π 3
This sounds like a fun job!
24.06.2025 08:03 β π 1 π 0 π¬ 0 π 0
Grant Cancellation Web Form
WAS YOUR GRANT CANCELED BY PRESIDENT TRUMP?
The Committee on Science, Space, and Technology, Democratic Staff, is surveying the impact of the Trump Administrationβs cancelation of federal research awards. If your award was terminated since January 20, 2025, please fill out this brief survey. If you had multiple awards terminated, please fill out a separate form for each award. While anonymous submissions will be helpful to the Committeeβs efforts, we encourage you to leave your contact information if you are open to having a confidential conversation with Committee staff. Please find our confidentiality policies at the following link β any information you share will be treated with these protections, regardless of your current affiliation with any current or former funding agency: https://democrats-science.house.gov/contact/whistleblower
Are you a PI of a federal grant cancelled by the Trump administration?
Please share your info with the Democratic Staff of the House Committee on Science, Space, and Technology, who launched this portal yesterday to track funding cancellations ππ§ͺ
forms.office.com/pages/respon...
29.05.2025 13:46 β π 317 π 289 π¬ 4 π 8
Industry friends, now is the time for MUCH more speaking out on behalf of academic colleagues under duress. Here are core open source methods that many of your products doubtlessly depend on either directly or indirectly (see en.wikipedia.org/wiki/HMMER) being abruptly defunded. Make noise.
29.05.2025 14:39 β π 76 π 50 π¬ 1 π 0
π¬ Hiring: Postdoctoral Fellow
Seeking a bioinformatician/screening expert to be part of our team running genomeβwide screens, building dataβintegration pipelines & validating hits in higher organisms.
π± 2βyr fellowship with tailored mentorship, leadership & scienceβcommunication training
18.04.2025 08:03 β π 8 π 7 π¬ 1 π 2
Come and join us in solving mystery of plasma membrane proteostasis in beautiful neurons.
10.04.2025 13:14 β π 1 π 1 π¬ 0 π 0
Pls re-skeet! There's a postdoc job available to join us in Bristol! We're looking for a molecular cell biologist to help us investigate plasma membrane proteostasis in neurons. Apply here by 23 April: www.jobs.ac.uk/job/DMO097/r.... If interested, do contact me and check out grieve-lab.com! Thanks!
09.04.2025 15:42 β π 9 π 15 π¬ 1 π 3
Protein structure of C1 bound to IgM antibodies
Our new lab website is online!
sharplab.uk
Check it out and learn more about our research in Bristol!
09.04.2025 08:36 β π 17 π 5 π¬ 0 π 0
Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization
Check out our new paper with Michael Landreh, @pstansfeld.bsky.social and others in @elife.bsky.social : Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization doi.org/10.7554/eLif...
27.03.2025 09:31 β π 14 π 5 π¬ 0 π 0
Applications close today for this @uniofmanchester.bsky.social #DigitalNotebook #Metascience project, seasoned with #OpenResearch & served with helpings of #ResearchIntegrity and a side of #ResearchCulture
Full details of everything on the menu below π
www.jobs.manchester.ac.uk/Job/JobDetai...
24.03.2025 13:12 β π 0 π 1 π¬ 0 π 0
Thank you Ines! I had such a lovely time visiting sunny York this week, sharing our science and chatting cell bio, neuroscience and proteases. Thanks for the invite, special thanks to the one and only @yorkyeast.bsky.social for top-notch hosting!
23.03.2025 12:04 β π 7 π 1 π¬ 0 π 1
An image montage advertising NeuroBioUK - 12th of September 2025 in York. The image is York cathedral superimposed over a fluorescent cortex mouse section coloured to look a bit like a dawn sky.
Do you need some science joy in your life? Do you like neurons? Maybe glia? Molecules? Cell biology? Save the date for #NeuroBioUK25 - the venue is booked and we are excited to see you and your incredible science there on the 12th of September!
neurobiouk.sites.sheffield.ac.uk
06.03.2025 07:57 β π 29 π 14 π¬ 1 π 2
An image montage advertising NeuroBioUK - 12th of September 2025 in York. The image is York cathedral superimposed over a fluorescent cortex mouse section coloured to look a bit like a dawn sky.
Save the date: We're excited that the third NeuroBioUK will take place on September. Block it in your calendar to join us in York for a fun day of neurons, glia, cool science and chats!
06.03.2025 09:23 β π 5 π 2 π¬ 0 π 0
Macrophages promote collagen deposition through circadian regulation of fibroblasts
Collagen deposition in fibroblasts, the primary collagen-producing cells, is regulated by both macrophages and the circadian rhythm, although how these regulatory processes interact with one another i...
Our lab's #1st manuscript from our #1st #PhD Katie is on #bioRxiv! Check it out ππ»
#macrophage regulation of fibroblast #collagen #circadian rhythm. #ImmunoECMatrix w/ @profandrewmac.bsky.social @tracyh9494.bsky.social @mcrcellmatrix.bsky.social @mcf-uom.bsky.social
www.biorxiv.org/content/10.1...
05.03.2025 08:28 β π 52 π 18 π¬ 0 π 1
Exciting opportunity in the newly minted McMillan lab in Liverpool. Kirsty is a great scientist and a top mentor for students - if youβre looking for a PhD and are interested in trafficking and neurodegeneration, do contact her!
18.12.2024 18:29 β π 1 π 1 π¬ 0 π 0
Thanks Loges, very kind of you!
10.12.2024 11:53 β π 1 π 0 π¬ 0 π 0
UK Membrane Trafficking Meeting 2024 | King's College London eStore
Registration for the 2024 UK Membrane Trafficking Meeting, held at KCL.  Registration per person, to include sandwich lunch and coffee breaks and even
UK Membrane Trafficking 2024
Who doesnβt like a deadline that gets brought forward?
Please register by 3rd December - Kingβs need longer to make the sandwiches than I previously thought!
estore.kcl.ac.uk/conferences-...
Programme coming soon!
25.11.2024 08:53 β π 21 π 17 π¬ 0 π 2
Amazing PhD opportunity to join an exciting new lab at Bristol Biochemistry - send your best students in Ferdosβ direction!
27.11.2024 12:36 β π 3 π 1 π¬ 1 π 0
This scheme shows the cargo adaptor FHF in the middle with arrows pointing to distinct microtubule and actin-based motors (dynein-dynactin, KIFC1, KIF1C and myosins V, IX and X as well as Tropomyosin 1). It also shows a link to Rab5 marked early endosomes. The hypothesis is that FHF coordinates multi motor binding at the early stages of endocytosis. The PhD project would address the hierarchy of motor binding and how these motors coordinate to allow the newly formed vesicle to transition from the actin to MT cytoskeletal network.
If youβre interested in how molecular motors coordinate to power intracellular trafficking events (e.g. endocytosis), Iβve got a PhD position available to study this at vibrant Bristol uni. In this project, we will capture highly dynamic events by #cryoEM, single molecule imaging & cell biology. π¬βοΈπ§ͺ
27.11.2024 12:15 β π 53 π 30 π¬ 1 π 7
Can I ask you to share a PhD advert at Bristol Uni please? Rhomboid proteases play a role in neurons that is essential for life- but it is not characterised. Got a student interested in cell biology, electrophysiology and neurobiology? Send them our way! tinyurl.com/56f24f7c
15.11.2024 17:55 β π 72 π 81 π¬ 1 π 4
Waves of new BlueSky arrivals in last few days!
Iβve been tracking starter packs relevant to molecular/mechanistic/genetic/cellularβ¦etc biology
Hope itβs helpful but warning: now a v long thread!
Probably the last time I can do this...
12.11.2024 15:03 β π 194 π 115 π¬ 16 π 19
Interested in:
- mitochondrial regulation and quality control related to Parkinson's Disease?
- novel hemi-channels for mitochondrial protein import/degradation?
- the structural basis of PINK1 recognition by PARL?
Then read this cool paper from the Collinson and Corey labs! tinyurl.com/2hhp5h35
08.11.2024 09:45 β π 2 π 1 π¬ 0 π 0
Want to work on a 4-year BBSRC-funded project to tag all Drosophila transcription factors with an exchangeable epitope? This is a 0.5 FTE Research Technician post. Come join our collaborative team and help cloning constructs, injecting fly eggs, and screening for transgenics. tinyurl.com/44mprcev
21.12.2023 17:51 β π 1 π 3 π¬ 0 π 0
Thanks Matthew - nice to be here!
20.12.2023 17:32 β π 2 π 1 π¬ 0 π 0
Chemical biologist @ Max Planck Institut for Medical Research in Heidelberg
Postdoctoral fellow, Huazhong University of Science and Technology #bioinformatics
Lise Meitner Research Group Leader at Max Planck Institute of Biochemistry, Munich, Germany | Biochemist in ADP-ribosylation research
Postdoc in Miller lab @UoDundeeLifeSciences.
Previous: #MSCAFellow @MRC_LMB; PhD @YaleChem; CCME @PKU1898
IDP/IDRs, membrane traffic, protein dynamics, evolution.
https://scholar.google.com/citations?user=-kHbQqwAAAAJ&hl=en
We are passionate about how cells squeeze through tiny in spaces in vivo, and how they get to divide and make fate decisions whilst they are at it!
We love fish, frogs, live microscopy and arts and crafts.
Associate Scientist at CRUK Scotland Institute interested in autophagy, cancer and inflammation.
#autophagy Mum and postdoctoral research associate at Simon Wilkinson lab in University of Edinburgh #WilkinsonLab
Beth Levine's Legacy Network
IntentΓ© ser azote de los malos...pero me quedΓ© a medio camino!!Todavia se podrΓ‘ poner un granito de arena, no?
Intentando mejorar el mundo desde Macphagy lab #USAL
Cell biologist excited about autophagy, quality control, evolution, and membrane trafficking. Reads and thinks about academic mentoring, equality & diversity. https://www.cos.uni-heidelberg.de/en/evolutionary-cell-biology
Senior Editor @Nature handling manuscripts in general cell biology and plant biology. Views expressed here are my own.
Cell Biologist working at Crick Institute @crick.ac.uk - Cytoskeleton, Arp2/3 iso-complexes, Signalling and Vaccinia Virus. Editor-in chief Journal Cell Science - @jcellsci.bsky.social - comments are my own opinion
Structural cell biology, biophysics, fluorescence, electron microscopy, art, nature. All opinions are my own.
The Faria Lab is based at University of York and studies nuclear architecture, genome organisation and biomolecular condensates in the context of gene expression regulation in trypanosomatids
ContactCTC is the only journal dedicated to discuss Inter-Organelle Communication. OpenAcess, PeerReviewed.
https://journals.sagepub.com/home/ctca From SAGE Publishing.
Editor-in-Chief: Tim Levine, UCL.
Molecular Mechanisms of Neurodegeneration Lab, assistent prof. interested in synaptic proteostasis and the ER.
Professor at ETH Zurich, studying how molecular nanoscale organization of the cellular surfaceome can be leveraged for diagnostic and therapeutic applications.