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Phil Wang MD

@lucidrains.bsky.social

Boston transplant now living in San Francisco with a border collie / lab mix

2,656 Followers  |  6,373 Following  |  124 Posts  |  Joined: 06.02.2024  |  1.9024

Latest posts by lucidrains.bsky.social on Bluesky

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07.08.2025 22:16 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Fact check:

mRNA vaccines for respiratory viruses are meant to prevent severe illness (bad Pneumonia).

This means beefing up our immunity in the *lower* respiratory tract, eg the lungs.

Kennedy talks about the *upper* respiratory tract and vaccine efficacy in nonsensical gibberish.

07.08.2025 14:35 β€” πŸ‘ 12619    πŸ” 4512    πŸ’¬ 640    πŸ“Œ 230

morons

07.08.2025 02:11 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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EBV induces CNS homing of B cells attracting inflammatory T cells - Nature Epstein–Barr virus infection generates a neuroinvasive B cell subset, which recruits activated T cells to the central nervous system, promoting multiple sclerosis.

How does Epstein- Barr virus induce multiple sclerosis?
The infection leads to B cells that get into the brain, attracting pro-inflammatory T cells (mouse model)
www.nature.com/articles/s41...

06.08.2025 15:24 β€” πŸ‘ 244    πŸ” 87    πŸ’¬ 9    πŸ“Œ 2
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31.07.2025 13:36 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Sensitization of tumours to immunotherapy by boosting early type-I interferon responses enables epitope spreading - Nature Biomedical Engineering Lipid particles loaded with RNA coding for tumour-unspecific antigens can enhance early responses of type-I interferons, mediating the success of immune checkpoint inhibitors as well as epitope spread...

Some important progress in vaccines
1. Cancer vaccine, potentially universal, to rev up immune system
www.nature.com/articles/s41...
2. Lipid nanoparticle improvement for better safety and potency
www.nature.com/articles/s41...
3. mRNA delivery by capsule www.statnews.com/2025/07/16/s...

18.07.2025 17:55 β€” πŸ‘ 249    πŸ” 82    πŸ’¬ 3    πŸ“Œ 1
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17.07.2025 15:03 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I’m tired of hearing from some peers how we β€œneed to hear out” the MAGA/MAHA point-of-view on health β€” in their effort to be the β€œadult” in the room.

Engaging in false equivalences and normalizing nonsense as serious debate will not move us towards some greater enlightenment.

14.07.2025 00:33 β€” πŸ‘ 1075    πŸ” 242    πŸ’¬ 66    πŸ“Œ 12
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09.07.2025 19:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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07.07.2025 20:08 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Let’s realize that both parties, when in power, have approved original Medicare and MA plans that enrich insurance companies at the expense of patients. Both parties let the HC industry get so opague, no one has a clue how the much care truly costs. Including most hospitals.

06.07.2025 19:36 β€” πŸ‘ 3165    πŸ” 426    πŸ’¬ 441    πŸ“Œ 47
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04.07.2025 00:53 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

wow

28.06.2025 20:40 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I'm not really sure, but I suggest rewinding to the checkpoint before and then setting `torch.autograd.set_detect_anomaly(True)` before resuming training to try to catch where it came from

26.06.2025 22:10 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | NEJM Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimisle...

New @nejm.org
Pluripotent stem cells for Type 1 diabetes restored pancreatic islet cell function, improved glucose regulation, and decreased the need for insulin in 14 participants #ADASciSessions www.nejm.org/doi/full/10....

21.06.2025 13:55 β€” πŸ‘ 242    πŸ” 58    πŸ’¬ 7    πŸ“Œ 4
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19.06.2025 13:59 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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2 years ago year to date, fossil gas output on California's main grid was 93% higher than solar output

In 2025, solar output is 32% higher than gas output

Gas output has dropped 41.4% and solar output has risen 50% in 2 years

Battery output has also risen 215%

15.06.2025 16:01 β€” πŸ‘ 203    πŸ” 73    πŸ’¬ 8    πŸ“Œ 11

#Vaccines are one of the greatest public health achievements ever.

☠️ #Smallpox killed ~30% of those infected
πŸ“† 300 million lives lost in the 20th century
🚫 Eradicated by 1980 thanks to vaccines

That’s the power of science. #VaccinesWork #PublicHealthWin

12.06.2025 02:06 β€” πŸ‘ 76    πŸ” 21    πŸ’¬ 0    πŸ“Œ 0
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12.06.2025 17:37 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Kennedy Removes All C.D.C. Vaccine Panel Experts

As expected, RFK Jr. was lying during his confirmation hearing and now is ratfucking the vaccination system in the US.

The vast majority of the public does not want this and yet again it’s clear that the Republican administration does not serve the electorate.

10.06.2025 00:02 β€” πŸ‘ 783    πŸ” 214    πŸ’¬ 32    πŸ“Œ 15
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The Bethesda Declaration

A call to stand up and show support for the Bethesda Declaration, the NIH, and for federally funded science in general.

09.06.2025 18:13 β€” πŸ‘ 120    πŸ” 59    πŸ’¬ 4    πŸ“Œ 2
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An Il12 mRNA-LNP adjuvant enhances mRNA vaccine–induced CD8 T cell responses IL-12 is dispensable for CD8 T cell responses to mRNA vaccination, but an Il12 mRNA-LNP enhances CD8 T cell memory and protection.

How adding mRNA to code for interleukin-12 markedly increased T cell immune response which could be used for vaccines vs infectious diseases and cancer @sciimmunology.bsky.social
www.science.org/doi/10.1126/...

07.06.2025 14:41 β€” πŸ‘ 374    πŸ” 86    πŸ’¬ 5    πŸ“Œ 5
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04.06.2025 19:13 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Cancelling the Moderna contract for a candidate Avian Flu vaccine simply means other countries will likely step in and fill the funding void.

Innovation will continue, just in our absence.

It also means higher prices for Americans if/when we need a vaccine for this quickly changing pathogen.

02.06.2025 12:37 β€” πŸ‘ 647    πŸ” 195    πŸ’¬ 26    πŸ“Œ 7

I'm seeing that many of the best use cases Redis users are applying vector sets to, are not related to learned embeddings. For instance, I have a friend that is doing a huge scale molecular search application, and they encode the molecule representation directly.

29.05.2025 07:55 β€” πŸ‘ 15    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

absolute unit

28.05.2025 22:02 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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28.05.2025 18:20 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Three of the most dangerous men in America right now are being propped up as voices of science and public health.

It’s horrifying this is what we’ve come to. This isn’t scientific integrityβ€”it’s political theater.

I wouldn’t trust these guys to give me a Band-Aid, let alone give medical advice.

28.05.2025 04:54 β€” πŸ‘ 43    πŸ” 15    πŸ’¬ 1    πŸ“Œ 0
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24.05.2025 18:21 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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22.05.2025 20:39 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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