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brad hightower

@brad-hightower.bsky.social

existential dilettante clinical trials // music // sneakers // absurdism // subversion // general tomfoolery hightowerclinical.com notetofilepodcast.com

73 Followers  |  129 Following  |  35 Posts  |  Joined: 25.01.2025  |  2.3619

Latest posts by brad-hightower.bsky.social on Bluesky

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a close up of a man in a military uniform looking at the camera with a serious look on his face . ALT: a close up of a man in a military uniform looking at the camera with a serious look on his face .

"France the Mute" is 20 years old

17.02.2025 14:35 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Guess we can always just drill for more oil.

08.02.2025 20:14 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Industry, not NIH, fronts most of the cash for clinical trials: report Industry spending far outpaces the U.S. National Institutes of Health (NIH) when it comes to clinical development, a new report has shown. | A new analysis shows that the NIH spent $8.1 billion on pha...

To be clear, I don't disagree that the whole situation is fucked.

www.fiercebiotech.com/research/rep...

08.02.2025 19:29 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

"I never thought the leopards would eat my face"

-Oklahomans, probably

08.02.2025 19:15 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

There are a lot of clinical trials that are industry sponsored and not impacted by this.

08.02.2025 19:10 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Genuine question but what is that $100m spent on? I run community research sites and only worked in academia briefly. I know pharma sponsored research is a different animal but I always thought those F&A rates were insanely high and never had any idea what they were actually going towards.

08.02.2025 17:31 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Yeah, but, you know... Money.

02.02.2025 18:04 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

i dunno man. lots of scientists out there saying "you know, clinical trials are too diverse. we gotta do something about that"

01.02.2025 14:50 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Any now it's gone. wtf. #clinicaltrials

01.02.2025 13:43 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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There's really not enough sneaker content on Bluesky.

KOTD

Air Jordan 3 x J Balvin 'Rio'

31.01.2025 15:52 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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We're #1, baby!

30.01.2025 04:02 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

lol. Look, I agree that it's fucked up. I still think it's important not to conflate treatment and research experiments. But, sure, point taken.

29.01.2025 05:56 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Just seeing an abstract. I'll message you. Thanks.

29.01.2025 05:04 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

this dude really creeps me out

29.01.2025 05:01 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

This is really cool. Is there somewhere I can read more about this?

29.01.2025 04:43 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

at the risk of being pedantic, clinical trials are not treatment.

29.01.2025 04:12 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Per an NIH source:

โ€œDiscussions with colleagues have suggested that if the universities all come together and raise hell about the delays to funding caused by not holding meetings, that might move the needle. From every state. There are well-funded universities in red states that will be impacted.โ€

28.01.2025 00:45 โ€” ๐Ÿ‘ 14611    ๐Ÿ” 3364    ๐Ÿ’ฌ 273    ๐Ÿ“Œ 190
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ok well. i guess that's that

28.01.2025 00:56 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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take 2

28.01.2025 00:34 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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I can't imagine why people wouldn't trust AI. Deepseek seems cool.

28.01.2025 00:32 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

This shit is pretty scary. #clinicaltrials

27.01.2025 23:48 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

amazing. thanks.

27.01.2025 18:40 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿ˜ญ

27.01.2025 18:10 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

It will depend on who is sponsoring the trial. Pharmaceutical company sponsored trials are not impacted. There should be contact info in the consent form they signed. They can call their PI or a coordinator to find out more.

26.01.2025 22:44 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

why don't we see more phase 3 platform trials in pharma? #clinicaltrials #clinicalresearch

26.01.2025 16:11 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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I don't disagree with this sentiment but informed consent forms are pretty clear about the uncertain nature of clinical trials. This is from a real study and is in pretty much every ICF for every study we perform. Either way, this sucks.

26.01.2025 16:08 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Enhancing the Diversity of Clinical Trial Populations โ€” Eligibility Cr Guidance for Industry

While the recent draft guidance for diversity plans in clinical trials has been taken offline, at least previous guidance still appears to be in tact.

There's that at least. I guess.

#clinicaltrials #clinicalresearch

www.fda.gov/regulatory-i...

26.01.2025 15:41 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Interesting article.

"These applications improve efficiency and reduce costs but are unlikely to significantly increase success probabilities or approval rates. Automation alone does not equate to scientific advancement"

26.01.2025 15:23 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Final secret files are coming out on the murders that shattered the 60s. What we may learn on JFK, MLK and RFK | CNN When President Donald Trump announced an executive order Thursday to release the remaining government files in three of the countryโ€™s most notorious assassinations, it immediately grabbed public atten...

It turns out that JFKs head did, in fact, just do that.

www.cnn.com/2025/01/25/u...

26.01.2025 02:03 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks! I have no idea what I'm doing. Yet.

25.01.2025 22:56 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

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