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Manush Sondhi

@manushsondhi.bsky.social

Rheumatology fellow@ University of Washington| IM@ LSU,Shreveport | KMC,Manipal

37 Followers  |  44 Following  |  13 Posts  |  Joined: 19.12.2024  |  1.5845

Latest posts by manushsondhi.bsky.social on Bluesky

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πŸ†• Secrets & Pearls of #Rheumatology at #ACR25 | Part 1 by Dr. Janet Pope

πŸ–οΈ Cutaneous Pathology SLE/DM
🧴 Tips for SLE 
πŸ’ͺ Cancer Screening in Myositis
🩸 Laboratory Testing
πŸ₯Ά Raynaud's / Scleroderma
πŸ‘€ Sjogrens Disease

#RheumSky #MedSky #Lupus #MyositisΒ #Scleroderma #Sjogrens

28.10.2025 23:02 β€” πŸ‘ 12    πŸ” 6    πŸ’¬ 0    πŸ“Œ 1
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Tune into Abstract Session this afternoon (3:00 - 3:15 PM CST) where Dr. Manush Sondhi, MD, will be presenting on "The Cost of Complexity: Financial Toxicity in Rheumatic Disease, Cancer, and Their Intersection!" #UWRheum #ACR25

28.10.2025 17:02 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Another heavy hitter presentation for #ACR25 's Thieves Market Presentation Series (10:30 AM CST - 12:30 PM CST), our very own, Dr. Manush Sondhi, MD, will be speaking on "The Hidden Choreography: When Joints Ache, Skin Cries, and the Heart Strains." Don't miss out! #UWRheum

28.10.2025 14:05 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Abs 2615 @manushsondhi.bsky.social @nasingh.bsky.social

πŸ“Š Data source: NHIS 2019-2023

πŸ”Ž Evaluated financial toxicity (related to medical care and medical condition) among those with rheumatic disease, cancer, both, or neither; and stratified by age (65 yrs)

#ACR25

27.10.2025 23:02 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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An extra special #ACR25 highlight:

Our superstar fellow, Dr. Manush Sondhi, MD, was listed as this year's ACR Foundation Award Receipient! We, #UWRheum, are extremely proud of his contributions to both the division and team environment. Way to go Dr. Manush!

27.10.2025 16:03 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Malignancy association with Ro52 positivity. #ACR25

27.10.2025 17:32 β€” πŸ‘ 3    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Another proud moment for #UWRheum, one of our very own, Dr. Manush Sondhi, MD, will be presenting during Poster Session A @ 10:30 AM CST: "Breaking Bones, Breaking Hearts: A FAERS Perspective on Osteoporosis Medications" #ACR25

27.10.2025 13:50 β€” πŸ‘ 4    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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YearInReview: dazukibart in inflammatory myositis. Too early for conclusions #ACR25

26.10.2025 13:50 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Why taper to ≀ 5 mg pred/d?
Strong recommendation
GULP study:
127 SLE pts starting pred 25 mg/d
(w/HCQor IS) within 12 mo. of SLEd (2yr f/u)
Daily Prednisone doses
Calcome in patients with newly
aosocclve oourtea وgoy
20
Patients (%)
31
80 mp 4
47
12
Time (months)
= β€Ή5 mgld
24
135 bul 25 mg/d
β€’ No difference in relapse rates (p=0.706) when tapering to <5 mg/d vs. not tapering < 5 mg/day (46.4%).
β€’ Every month on pred <5 mg/day β†’ lower damage accrual (IRR: 0.96; p=0.007)
β€’ Never tapering pred <5 mg/day β†’ higher risk of GC-related damage (OR 5.9;
p=0.014).
β€’Tapering pred <5 mg/day was achieved + maintained in half of newly diagnosed patients with SLE.

Why taper to ≀ 5 mg pred/d? Strong recommendation GULP study: 127 SLE pts starting pred 25 mg/d (w/HCQor IS) within 12 mo. of SLEd (2yr f/u) Daily Prednisone doses Calcome in patients with newly aosocclve oourtea وgoy 20 Patients (%) 31 80 mp 4 47 12 Time (months) = β€Ή5 mgld 24 135 bul 25 mg/d β€’ No difference in relapse rates (p=0.706) when tapering to <5 mg/d vs. not tapering < 5 mg/day (46.4%). β€’ Every month on pred <5 mg/day β†’ lower damage accrual (IRR: 0.96; p=0.007) β€’ Never tapering pred <5 mg/day β†’ higher risk of GC-related damage (OR 5.9; p=0.014). β€’Tapering pred <5 mg/day was achieved + maintained in half of newly diagnosed patients with SLE.

Hydroxychloroquine Recommendations:
β€’ Routinely treat with HCQ unless
ACR
Convergence
Where Rheumatology Meets
contraindicated. (S)
β€’ Continue therapy indefinitely, even if sustained remission. (C)
β€’ Aim for long-term average daily dose goal of ≀5 mg/kg (C)
β€’ Preferred over >5 mg/kg to minimize retinal toxicity
β€’ Use of short courses of higher dose (5-6.5 mg/kg/d) therapy may be necessary at initiation of treatment, to maintain disease control, or during pregnancy.
No recommendation regarding utilization of HCQ levels
S: strong recommendation C: conditional recommendation

Hydroxychloroquine Recommendations: β€’ Routinely treat with HCQ unless ACR Convergence Where Rheumatology Meets contraindicated. (S) β€’ Continue therapy indefinitely, even if sustained remission. (C) β€’ Aim for long-term average daily dose goal of ≀5 mg/kg (C) β€’ Preferred over >5 mg/kg to minimize retinal toxicity β€’ Use of short courses of higher dose (5-6.5 mg/kg/d) therapy may be necessary at initiation of treatment, to maintain disease control, or during pregnancy. No recommendation regarding utilization of HCQ levels S: strong recommendation C: conditional recommendation

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2025 ACR Lupus Guideline - Overview presented by Dr. Lisa Sammaritano.
Key take aways:
β€’ HCQ should be standard therapy
β€’ Use GC with precision
β€’ Introduce immunosuppressive therapies early
β€’ Use shared decision-making when considering treatment decisions

#ACR25

26.10.2025 14:22 β€” πŸ‘ 9    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
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The 2025 ACR extrarenal SLE guideline includes 36 graded recommendations

πŸ”‘HCQ= standard therapy
πŸ”‘GCs to control initial inflammation/flare; taper ASAP
πŸ”‘Early use of immunosuppressive therapies
πŸ”‘Shared decision making

#ACR25 #ACRambassador

26.10.2025 14:49 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Post image 19.10.2025 20:33 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Excited to see you tomorrow, Namrata!!

29.09.2025 19:38 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks Jean :) Congratulations Jamie!!!

29.09.2025 19:37 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks Jamie!! Congratulations to you too!!! Amazing jobπŸ‘

29.09.2025 19:36 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Grateful to my amazing mentor, @nasingh.bsky.social for all the guidance and support! #ACR25

29.09.2025 02:04 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 3    πŸ“Œ 0

Let’s do it!!!

27.09.2025 04:49 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank You :)

16.09.2025 06:20 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks, Jean for the wishes! Super excited!!

16.09.2025 06:20 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Honored to receive the Marshall J. Schiff, MD Memorial Fellow Research Award at #ACR25! Grateful for the support of my wonderful mentor @nasingh.bsky.social

30.08.2025 22:00 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 1    πŸ“Œ 1

We used 2019-2023 National Health Interview Survey Data

04.08.2025 22:43 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks Jean. We found that Rheumatic diseases are linked to higher financial toxicity than cancer, especially in younger adults. Chronic conditions carry lasting costs; it's time we recognize and address them.

04.08.2025 22:30 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Grateful and excited - 2 abstracts and a Thieves Market case accepted to ACR! Can’t wait for my first oral podium presentation at #ACR25

04.08.2025 22:13 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 1
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Thrilled to share that my second CPC is published in the February 25 edition of Arthritis Care & Research! Even more excited that the cover image for the issue is from my article πŸ₯³

28.01.2025 03:49 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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