Blaise Frederick

Well, obviously yes, because it rains now.

They have no interest in making their own lives better or more enjoyable. They are really only motivated by making other people’s lives worse.

Living systems are extremely complex. If you could fully model them to a sufficient level of detail that you could predict what they’d do in every situation, that would be great, but we’re nowhere near that.

All of the things listed exist and are useful, but “alone, or in combination with animal models” is doing a LOT of heavy lifting.

“ChatGPT, alone or in combination with humans, can do anything humans can do”.

I think it’s as simple as the fact that anybody still on Twitter at this point is fine with the way it is over there. Everybody who was bothered has left at this point.

Repeal the Permanent Apportionment Act of 1929. That would uncap the size of the House and make the distribution of Representatives more closely match the actual population of the US. It would also make the electoral college vote better represent the actual population vote.

It is a travesty that this bill is even coming to a vote. Thank you for being there to stand up for your constituents.

Oh but he does care. He’s trying to maximize the number of people he hurts.

And some don’t feel any need to obtain consent at all.

Because we're doing a data driven analysis using signals from within the brain, we don't have to make any assumptions about how the RRF or RV waveforms show up in the BOLD signal (the tacit assumption here is that the relationship is linear, which isn't a bad assumption though).

+/-3-3.5 seconds will almost span the range of normal delays within the brain (assuming you've already delayed the RRF and RV regressors to account for transit time TO the brain), but if you have pathology, or even normal aging, that may not be broad enough.

So I think the approach in the paper is pretty good, but I think voxel specific regressors are better because they are parsimonious and minimize the loss of degrees of freedom. They can also deal with arbitrary delay magnitudes.

Hey - I know I'm a bit late to this... Adding a temporal derivative deals with small delays (up to maybe 3-3.5 seconds in either direction for LFO signals). As far as I've been able to determine, blood flow through the brain is non-dispersive. So don't know if a dispersive derivative is needed.

If you won't fight for yourself, why on earth would a client think you'd fight for them?

_Everything_ pushes them further right.

Check out this tour de force paper by @tsbolt.bsky.social showing the relationship between the autonomic nervous system and the global signal in fMRI!

I'm happy to announce that rapidtide 3.0 has finally escaped from its development dungeon and has been released! rapidtide.readthedocs.io/en/stable/wh...

And John McCain

How terrible for them. The terrible consequences were only supposed to affect 99% of the population, not the people who matter. So sad.

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I think gemini.google.com appends "as drawn by Picasso" to the prompt.

If anybody hasn't seen this - this is a really cool method for looking at dopamine physiology using fMRI!

“When the revolution comes, everything will be different. Not better. Just different.”

I think the average person doesn’t have any idea about this, which is why they aren’t more freaked out.

Brain reactivity to nicotine cues mediates the link between resting-state connectivity and cue-induced craving in individuals who smoke or vape nicotine - Neuropsychopharmacology Neuropsychopharmacology - Brain reactivity to nicotine cues mediates the link between resting-state connectivity and cue-induced craving in individuals who smoke or vape nicotine

I'm happy to share our paper in @npp-journal.bsky.social on rsFC, cue-reactivity, and craving in nicotine smoking AND vaping! Thanks to coauthors, @amy.janeslab.org @blaisefrederick.bsky.social @ckorponay.bsky.social @mariascavnicky.bsky.social Here's what we found 🧵 www.nature.com/articles/s41...

It’s just like Schindler’s list, except instead of saving people, he’s cynically tacking to the right to suck up to MAGA voters for his own personal political benefit. But otherwise exactly the same.

This needs more visibility! While the general public is belatedly getting some sense of the catastrophe caused by not reviewing or funding external grants, DOGE is also completely wiping out the NIH intramural programs, which is just as bad, but is flying under the radar because NIH is gagged.

Knowing them, almost certainly both.

Vermont understood the assignment.
Take notes, America.

Kinda baffled too. Given the apparent zeal for whacking science, why hasn't Big Pharma been putting the squeeze on Senators to protect their turf (RFK, NIH, NSF, etc.)?

Are execs in denial? Too focused on short-term results? Or do they not understand their own scientific pipelines?

Corporate America just had to sit at the end of the scientific pipeline, plucking off the most promising results via the magic of "technology transfer", + then develop more advanced products to sell

All the risks of basic research were socialized, + the gains privatized

Capitalist utopia!