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Maurice Lab

@mauricelab.bsky.social

Exploring the dual nature of signals, particularly Wnt signaling, in homeostasis and cancer using organoids and proteomics to uncover patient-specific mechanisms. Founder of Laigo Bio. Center for Molecular Medicine | Oncode Institute | madelonmauricelab.nl

62 Followers  |  51 Following  |  7 Posts  |  Joined: 09.12.2024  |  1.4848

Latest posts by mauricelab.bsky.social on Bluesky

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Yesterday, @antonvenhuizen.bsky.social successfully defended his thesis "Molecular mechanisms of the
Ξ²-catenin destruction complex in health and disease", which describes the versatile field of WNT regulator AXIN1.

We are super proud and wish Dr. Venhuizen all the best in Cambridge!

08.05.2025 07:39 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Center for Molecular Medicine

Our Center for Molecular Medicine (cmmutrecht.eu) at UMC Utrecht, NL, is looking for a Principal Investigator in the field of fundamental Cancer Biology! The vacancy states tenure track level, but candidates with a more advanced career are very welcome to apply. shorturl.at/KZeYQ. Please repost!

07.02.2025 12:09 β€” πŸ‘ 5    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0

Want to learn the latest insights on how Wnt signaling controls cell behavior?
Check out a new review by Madelon Maurice (@madelonmaurice.bsky.social) and Stephane Angers at @natrevmcb.bsky.social

29.01.2025 12:21 β€” πŸ‘ 10    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Great work by @joepsprangers.bsky.social and more members from the lab! And that 3 days after receiving his doctorate!!!πŸŽ“

22.12.2024 22:31 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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WNT7B drives a program for pancreatic cancer subtype switching and progression Hyperactivation of WNT signaling is a well-established hallmark of cancer. Various epithelial cancers express high levels of WNT7B and WNT10A that are not commonly expressed during tissue homeostasis,...

Pre-print Alert! πŸ“’
Proud to share our insights on WNT7B driving pancreatic cancer progression. Sprangers et al uses organoids to show that WNT7B employs short-range signaling driving tumor growth and mediate a shift of PDAC cells towards a more aggressive phenotype

www.biorxiv.org/content/10.1...

22.12.2024 20:30 β€” πŸ‘ 16    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0
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πŸŽ‰ Huge congratulations to Dr. Joep Sprangers! Yesterday, Joep successfully defended his PhD thesis and officially became a doctor! His studies describe the role of WNT7B and WNT10A in regeneration, homeostasis, and cancer.
It was a very special day, couldn’t be prouder.

19.12.2024 11:14 β€” πŸ‘ 11    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Yesterday, our lab turned festive for late Sinterklaas/early Christmas! 🎁 With poems, laughter, and guessing games, we shared stories, gifts, and some surprising personal details. Add drinks, snacks, and a digital fireplace, and it was a night of bonding, cheer, and fun!✨#LifeOutsideTheLab

11.12.2024 11:32 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Our first post on BlueSky is here πŸ¦‹. Great story from @antonvenhuizen.bsky.social from our lab describing the role of AXIN1 mutations in hepatocellular carcinoma. Congrats to Anton for the hard work and the deserved BioRxiv pre-publication! πŸ₯³

www.biorxiv.org/content/10.1...

09.12.2024 11:53 β€” πŸ‘ 7    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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