Samantha Aguilar, PharmD, BCIDP, AAHIVP

ID Things to Be Grateful for -- 2025 Edition Looking back on these annual Thanksgiving posts, I notice an odd pattern: every few years, the intro turns into a kind of apology. As in, Yes, I know the title sounds upbeat, please don’t attack me. T...

Can we really be grateful for anything in the ID world in 2025?

Sure -- plenty of great advances!

Here are a half-dozen to celebrate (and be grateful for) in 2025, believe it or not. #idsky
blogs.jwatch.org/hiv-id-obser...

Decades of rigorous and scientifically sound research have proven that vaccines do not cause autism. CDC’s decision to change language on its website reversing that finding is reckless & harmful.

Our statement w/ @hivma.bsky.social, APIC, @sheaepi.bsky.social & @sidpharm.bsky.social: bit.ly/3XEc0KH

“Since 1998, independent researchers have conducted more than 40 high-quality studies involving over 5.6 million people. The conclusion is clear and unambiguous: There’s no link between vaccines and autism." -Dr. Susan Kressly, AAP President on recent changes to the CDC's website

Apply to our PGY1 Pharmacy Residency Program at Ochsner LSU Health Shreveport!

💊 Learn more about our program: lnkd.in/eftPgv36 💊

#PharmacyResidency #PGY1 #OchsnerLSUHealth #PhORCAS #ClinicalPharmacy #ASHP #PharmacyLeadership #ResidencyRecruitment

The updated SOFA-2 scores was released today!

It updates original SOFA score with more contemporary practices.

#IDSky

jamanetwork.com/journals/jam...

There is still a widespread belief that fever is harmful and that it should be
treated regardless of the underlying cause, which is not supported by clinical data.
🆕💫 Review: Fever in sepsis revisited: Is a little heat what we need? #idsky
academic.oup.com/ofid/article...

Bictegravir, emtricitabine, and tenofovir alafenamide versus ritonavir-boosted protease inhibitor-based antiretroviral therapy in people with HIV and viral suppression on second-line therapy in Haiti:... Patients on second-line protease inhibitor-based regimens in low-income and middle-income countries have high rates of nucleoside reverse transcriptas…

When we care for PWH who have virologic suppression, but possible or confirmed NRTI resistance, can we switch them to a simple oral treatment -- once-daily BIC/FTC/TAF? This study says yes, with results strengthened by proviral DNA testing. #IDSky #HIVSky www.sciencedirect.com/science/arti...

Must read for all teams consulting infectious diseases #idsky #idmeded #meded #stewardship #voicesofID @cidjournal.bsky.social
academic.oup.com/cid/advance-...

🏭 Manufacturers work with CLSI & FDA to stay aligned and update breakpoints efficiently.
🎙️ Hear Andrea Prinzi break it down on Let’s Talk Micro — brought to you by bioMérieux.
👉 Listen: asm.org/podcasts/let...

#AST #Breakpoints #Microbiology #LetsTalkMicro #bioMérieux

Propensity-Matched Comparison of Timely vs. Delayed Antibiotic Therapy in Stenotrophomonas maltophilia Pneumonia Stenotrophomonas maltophilia, a multidrug-resistant nosocomial pathogen, is associated with high mortality and therapeutic challenges...

Propensity-Matched Comparison of Timely vs. Delayed Antibiotic Therapy in Stenotrophomonas maltophilia Pneumonia

✅ Just Accepted
⭐ Editor's Choice
#IDSky

Finally published
🆕🔥DOTS RCT
Among participants with complicated S aureus bacteremia who achieved blood culture clearance, dalbavancin was not superior to standard therapy for achieving a more desirable outcome at day 70 #idsky
jamanetwork.com/journals/jam...

Dalbavancin for Treatment of Staphylococcus aureus Bacteremia This clinical trial compares the efficacy and safety of dalbavancin vs standard therapy for completion of treatment of complicated Staphylococcus aureus bacteremia in hospitalized patients.

DOTS trial is published!

It will be interesting to see how data correlates with SNAP.

jamanetwork.com/journals/jam...

Thanks to @jonathanrydermd.bsky.social and @kenkoonwong.bsky.social for letting me know!

#IDSky

Clinical consequences of delaying implementation of long-acting antiretroviral therapy for people with HIV and persistent viremia in the US CAB/RPV for people with HIV and persistent viremia in the US would lead to more viral suppression and fewer deaths compared to oral-based ART regimens. Inc

Clinical consequences of delaying implementation of long-acting antiretroviral therapy for people with HIV and persistent viremia in the US

✅ Just Accepted
⭐ Editor's Choice
#IDSky

Propensity-Matched Comparison of Timely vs. Delayed Antibiotic Therapy in Stenotrophomonas maltophilia Pneumonia Stenotrophomonas maltophilia, a multidrug-resistant nosocomial pathogen, is associated with high mortality and therapeutic challenges due to resistance.

Propensity-Matched Comparison of Timely vs. Delayed Antibiotic Therapy in Stenotrophomonas maltophilia Pneumonia

✅ Just Accepted
⭐ Editor's Choice
#IDSky

⭐️ 📄 ⭐️

Recently @pharmermeg.bsky.social updated this open-access post. Originally published in 2017, the new version has a complete overhaul & provides a downloadable document. This is an article that has been read by by tens thousands of people 🌎🌍🌏.

www.idstewardship.com/cross-reacti... #IDsky

I know RFK Jr. has assembled a quack crew to concoct a study showing otherwise but here is an new important large cohort study of over 1.2 million children in Denmark showing no association Aluminum adsorbed vaccines and chronic dz in childhood including autism.
www.acpjournals.org/doi/10.7326/...

Taxonomy shift 🚨
Candida auris has been reclassified as Candidozyma auris (C auris ) to reflect its distinct genetic profile from other Candida species. #IDSky #microsky

YouTube video by American Society for Microbiology Bactericidal vs Bacteriostatic Antibiotics - Editors in Conversation Podcast, Live from ASM Microbe

Bactericidal vs Bacteriostatic Antibiotics. This controversial topic has important conceptual ramifications to treat severe infections. youtu.be/3z4BItBrzbk

1/ The first #ACIP meeting with RFK Jr.’s handpicked members wrapped up yesterday. Over 4,000 tuned in—a level of attention we haven’t seen since the pandemic. And for good reason: these meetings shape vaccine policy, coverage, timing, access and availability. Here's what happened 👇

RFK Jr. ousts entire CDC vaccine advisory committee Health Secretary Robert F. Kennedy Jr. has removed every member of a scientific committee that advises the Centers for Disease Control and Prevention on how to use vaccines.

RFK Jr.‘s extreme anti-vax views — and his related conflicts of interest — were a huge problem during his confirmation process.

So he promised not to change the vaccine advisory panel.

Today, he fired every single expert on that panel. It's a public health disaster.

Today more than ever I think it is important to remind ourselves that #ElonMusk led indiscriminate cuts which have resulted in the estimated deaths of over 300,000 people globally to date. 2/3rds of these are children!!!
He is still very much a villain.
www.impactcounter.com/dashboard?vi...

RFK Jr.'s MAHA Report Cites Research Studies That Don't Exist Health and Human Services Secretary Robert F. Kennedy Jr.'s MAHA Report featured several seemingly fake studies and incorrect attributions.

Um. 🤔Who could have known these citations were fake…🤷‍♀️

Kennedy R. Brain worms: Unlocking creativity and spontaneous bad ideas. Inst Fake Neurol 2024;42(3):123-124.

Prasad M. COVID-19: Panic shopping and other pandemic benefits. Pandemics J. 2023;15(2):45-46.

www.rollingstone.com/politics/pol...

Variability in Durations of Therapy for Gram-Negative Bloodstream Infections and Factors Associated with Prolonged Durations In this study of 4,240 GN-BSI episodes during 2019 from 24 U.S. hospitals, the median duration of therapy was 12 days (IQR 9-15); 59% were treated for >10 days. There was marked variability in treatment durations across hospitals.

Variability in Durations of Therapy for Gram-Negative Bloodstream Infections and Factors Associated with Prolonged Durations

✅ Just Accepted
⭐ Editor's Choice
#IDSky

Happy infectious diseases pharmacist day 💊🧫🦠 love being able to advocate for AMS, ID DDI, and optimize cost effective therapy for our patients and institution! #IDPharmacistsDay #SIDPAdvocacy #FutureOfIDPharmacy #PharmacistsLeadingChange @sidpharm.bsky.social

Improved Detection of HIV-1 Drug Resistance with Droplet Digital PCR: A Comparative Study and Its Implications HIV drug resistance (HIVDR) is a crucial factor in treatment failure. Sanger sequencing, the current gold standard for resistance testing, cannot detect low-abundance variants constituting less than 20% of the virus population.

Improved Detection of HIV-1 Drug Resistance with Droplet Digital PCR: A Comparative Study and Its Implications

✅ Just Accepted
#IDSky

If you say you love freedom but you don’t believe freedom is for everybody, then the thing you love isn’t freedom. It’s privilege.

@governorwalz.mn.gov

A graph showing the adjusted population-attributable fraction of obesity classes for prevalent health conditions

“Our study demonstrated associations between obesity, particularly severe obesity, and the incidence of 16 common health outcomes.” 📋 Read the full study results by Z. Yao et al. in NEJM Evidence: eviden.cc/4iIRjGg

#MedSky #EndoSky

wow...and sad.

Top 5 Infectious Disease News Stories Week of April 26-May 3 Contagion® is a news resource for infectious disease specialists and practitioners, aiding identification, diagnosis, treatment and prevention.

This week, rising tick-borne illnesses from warmer winters, strong hepatitis E vaccine efficacy during an outbreak, emerging fungal threats and resistance, and more from Contagion. #IDsky #MEDsky

Read more: www.contagionlive.com/view/top-5-i...

Dose Optimization as a Strategy to Improve Clinical Outcomes and Suppress Antimicrobial Resistance From the discovery of penicillin to PK-PD principles: A brief historical overview and what we have learned from recent clinical trials.

In our Spring issue: From the discovery of penicillin to PK-PD principles: A brief historical overview and what we have learned from recent clinical trials. Dr. Alwin Tilanus writes on this topic. #IDsky #Medsky