Shahaf Peleg

Chameau (HBO1) regulates starvation resistance in Drosophila melanogaster in a temperature-dependent manner The body temperature of Drosophila melanogaster depends on the extrinsic temperature. Numerous studies show that environmental temperature influences metabolism, lifespan, and starvation resilience. W...

www.life-science-alliance.org/content/9/1/...

The mammalian longevity associated acetylome - Nature Communications Acetylome and proteome data analysis across 107 mammalian species identifies significant longevity-associated acetylated lysines. This study proposes a link between protein acetylation conservation an...

www.nature.com/articles/s41...

NSF halts grant awards while staff do second review Action comes after DOGE team arrives at science agency

www.science.org/content/arti...

There are two kinda separated themes in aging, that are sometimes wrongly mixed. The first is the improve healthy life span within the current lifespan limitations, and the other, to breach the glass ceiling of living pass 120.

#aging

I am excited to speak at #ARDD2025, the world’s largest conference on aging research and drug discovery! Join me in Copenhagen, August 25-29, 2025 to connect with top scientists, biotech pioneers, pharma leaders, and investors driving innovation in longevity science.

Register now: agingpharma.org

Xenotopic synthetic biology: Prospective tools for delaying aging and age-related diseases Using enzymes from lower organisms, which are not encoded in the mammalian genome, delays aging and age-related diseases.

www.science.org/doi/10.1126/...

Interesting new meeting on aging!

forum.2060.life

Its much easier to put yourself in someone else’s shoes and try to understand their motives than to put yourself in someone else’s shoes who cannot put himself in someone else’s shoes

Are there any investors/angels interested in eye aging?

Innovations in aging biology: highlights from the ARDD emerging science & technologies workshop

www.nature.com/articles/s41...

Chameau (HBO1) regulates starvation in a temperature-dependent manner in Drosophila melanogaster The body temperature of Drosophila melanogaster depends on the extrinsic temperature. Numerous studies in fruit flies have shown that environmental temperature has an effect on metabolism, lifespan an...

I really love this story! Two degrees....make the whole difference in terms of survival during starvation! Amazing work by the talented Anuroop!

Chameau (HBO1) regulates starvation in a temperature-dependent manner in Drosophila melanogaster

www.biorxiv.org/content/10.1...

Sodium butyrate is incorporated into central metabolism in fly head while inducing oxygen consumption increase Butyrate has been proposed as a drug therapy by acting as a lysine deacetylase (KDAC) inhibitor and elevating protein acetylation, in particular on histones. Nonetheless, recent studies suggest that t...

Something small to start the year

journals.plos.org/plosone/arti...

Keynote by Shahaf Peleg

My talk at Curious 2024

www.curiousfutureinsight.org/media-librar...

Vitalia Forever / Jan6 → Mar3, 2025 / Roatán, Honduras Join the legendary pop-up city seeding a hub for longevity biotech acceleration. If you believe tech is the force for progress you’ll find your tribe in Vitalia

Join us at Roatan! Viatlia 2025 starts:)

www.vitalia.city

Marked inflammatory response to ink of a tattoo

How tattoo ink induces inflammation and impairs the response to a Covid vaccine
www.biorxiv.org/content/10.1...

Starting from scratch?

#aging

You can try ignoring it, however if you really wish to see human live pass 120, you must invest in new lines of thoughts. Investing in diet/exercise/drugs that activate or inhibit a single "in-program" pathway, will not only not achieve your goal but also inhibit promising ideas
#aging