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Max J. Kellner

@mjkellner.bsky.social

Molecular biologist learning from the natural world. Now part of @www.helmholtz.de – aiming to decode disease resilience in bats and other remarkable species

103 Followers  |  306 Following  |  1 Posts  |  Joined: 05.04.2025  |  1.4021

Latest posts by mjkellner.bsky.social on Bluesky

Lichtmikroskopische Aufnahme eines Darmorganoides aus Gewebe von Nilflughunden

Lichtmikroskopische Aufnahme eines Darmorganoides aus Gewebe von Nilflughunden

🦇 Fledertiere können verschiedene hochgefährliche Viren in sich tragen, ohne sichtbar zu erkranken. @mjkellner.bsky.social & @penningerlab.bsky.social haben nun die zellulären antiviralen Abwehrmechanismen in den Schleimhäuten der Tiere untersucht.
www.helmholtz-hzi.de/media-center...

21.05.2025 09:58 — 👍 16    🔁 7    💬 1    📌 1
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Bat organoids reveal antiviral responses at epithelial surfaces - Nature Immunology Kellner et al. develop respiratory and intestinal organoids from Rousettus aegyptiacus to show elevated basal expression of interferon-ε (IFNε) and IFN-stimulated genes, along with robust, self-amplifying type III IFN responses that drive antiviral defense against zoonotic RNA viruses.

Hi 🦋 I’m thrilled to share that our #bat #organoid work has found a publishing home in Nature Immunology!

These models provided unprecedented insight into antiviral immunity at epithelial surfaces of the Egyptian fruit bat 🦇 — a natural reservoir of Marburg virus 🦠

www.nature.com/articles/s41...

21.05.2025 19:14 — 👍 45    🔁 11    💬 1    📌 3

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