Pauli Group (posts by Andi Pauli)

A big welcome for @svenklumpe.bsky.social to the @viennabiocenter.bsky.social

A huge round of applause and big congrats to all of you for leading the way in training the next generation of #zebrafish researchers around the world at the @mblscience.bsky.social in Woods Hole!

Evolutionary repurposing of a DNA segregation machinery into a cytoskeletal system controlling cyanobacterial cell shape Bacteria, despite their diversity, use conserved cytoskeletal systems for their intracellular organization. In unicellular bacteria, the ParMRC DNA partitioning apparatus is well known for forming act...

One of the most exciting discoveries from our lab so far is now online as a preprint!

Read a story on how the ParMR and Min systems started to collaborate to create the CorMR cytoskeleton, which now controls cell shape in multicellular cyanobacteria:
www.biorxiv.org/content/10.1...

Huge congrats to Clemens Plaschka, @ehannezo.bsky.social, @nvastenhouw.bsky.social, @schuldinerorenlab.bsky.social and all newly elected @embo.org members!

Outstanding life scientists elected to the EMBO Membership – Press releases – EMBO Sixty-nine new members join the community of leading life scientists in Europe and beyond

Big congratulations to all the newly elected @embo.org Members!
A special shoutout to @impvienna.bsky.social #ClemensPlaschka for this well-deserved recognition.
Your contributions to life sciences continue to inspire and I count myself lucky to work with you!

The fascinating work spearheaded by Kirsten Senti on the diversification and adaptation of endogenous retroviruses in the host gonad 'ecosystem'' is officially published.

At least for science in the #oocyte community, the future looks bright with so many curious & young minds thinking about big open questions in oocyte and reproductive biology! Thanks so much to @mhverlhac.bsky.social and @bokelab.bsky.social for organizing and bringing us all together in Paris!

Can’t believe I had the chance to visit beautiful Paris and connect with the amazing #oocyte community! Thank you @mhverlhac.bsky.social and @bokelab.bsky.social for bringing together a fantastic group of speakers and organizing the meeting in such a stunning venue. Can’t wait for the next one! 🥚

DaniocellDesktop logo, depicting a fish on a laptop screen.

If you love Daniocell, but wish it could generate analyses specific to YOUR genes & cell types of interest, check out DaniocellDesktop - a new point-and-click app for Mac and Windows that enables reanalysis of the Daniocell data without programming: daniocell.nichd.nih.gov/desktop/ (1/4)

Great to connect with this wonderful scientific community - a wide range of scientific questions united by a model organism perfect to study many fascinating biological phenomena! 🐠 Happy to be part of it!
#NOTHO25 #killifish

REFEREE 1: “I conclude with a simple, direct statement - this is the best paper I have read all year!”
#TransparentPeerReview

Co-evolving infectivity and expression patterns drive the diversification of endogenous retroviruses
@juliusbrennecke.bsky.social et al

www.embopress.org/doi/full/10....

Big congratulations to our postdoc Victoria @vdeneke.bsky.social for winning this year's Chi-Bin Chien Award from the International Zebrafish Society @izfs.bsky.social, which honors not only scientific excellence but also a Victoria's fabulous skills in mentoring & scientific outreach. Big congrats!

🎉Congratulations to IMP postdoc @vdeneke.bsky.social, from the @pauligroup.bsky.social, who received the International Zebrafish Society’s Chi-Bin Chien Award for her scientific and personal contributions to the zebrafish research field.

➡️Read more: www.imp.ac.at/news/article...

Silencing mitochondrial gene expression in living cells Mitochondria fulfill central functions in metabolism and energy supply. They express their own genome, which encodes key subunits of the oxidative phosphorylation system. However, central mechanisms u...

Researchers in Science have developed a tool to silence specific mitochondria-encoded mRNAs in living cells, which could help scientists understand the origins of certain mitochondria-related diseases. scim.ag/3F6Wm5d

Bat organoids reveal antiviral responses at epithelial surfaces - Nature Immunology Kellner et al. develop respiratory and intestinal organoids from Rousettus aegyptiacus to show elevated basal expression of interferon-ε (IFNε) and IFN-stimulated genes, along with robust, self-amplifying type III IFN responses that drive antiviral defense against zoonotic RNA viruses.

Hi 🦋 I’m thrilled to share that our #bat #organoid work has found a publishing home in Nature Immunology!

These models provided unprecedented insight into antiviral immunity at epithelial surfaces of the Egyptian fruit bat 🦇 — a natural reservoir of Marburg virus 🦠

www.nature.com/articles/s41...

We are hiring! Join the BioOptics team as a Data Scientist in Image Analysis and contribute to the team’s mission of providing microscopy applications, flow cytometry, and image analysis services. Link below. #europe #research #lifesciences

Thank you Laura for all your help and contributions by being an active conference participant!

For all zebrafish folks - seems like there is finally a good/better zebrafish annotation! Check it out - and thanks to Shawn and his team for putting this together!

Well done, Lorenz! And congrats also to Jacqueline Cordes from the Stingele lab for winning the other @embojournal.org sponsored poster award!

A big thank you to members of @pauligroup.bsky.social & @haselbachlab.bsky.social for ensuring a smooth meeting, and of course to our amazing conference organizer Manuela Steurer @impvienna.bsky.social - what would we organizers (O. Rissland, S. Shao, E. Bennett, myself) have done without you!

And big congratulations to our two winners of the @embojournal.org sponsored poster prizes, Jacqueline Cordes from @jstingele.bsky.social lab and @lgrundmann.bsky.social from the @haselbachlab.bsky.social!

The 2nd edition of the @embo.org workshop 'RNA meets Protein Decay', this time here in Vienna @impvienna.bsky.social, came to an end. Thanks to everyone who came and contributed to the great vibe of sharing science, discussing ideas and connecting with each other!

Structural basis of lipid transfer by a bridge-like lipid-transfer protein - Nature The LPD-3 complex structure reveals protein–lipid interactions that suggest a model for how the native LPD-3 complex mediates bulk lipid transport and provides a foundation for mechanistic studies of ...

Hugely significant finding for contact site research - can’t wait to read properly!
www.nature.com/articles/s41...

Cup? Platter? Stained glass? Our imaginations were inspired (even during uncertain times!) by these beautiful molecular complexes: the Erlin and prohibitin complexes implicated in quality control at the ER and mitochondria, respectively. Check them out here: www.biorxiv.org/content/10.1...

An optogenetic toolkit for robust activation of FGF, BMP, and Nodal signaling in zebrafish Cell signaling regulates a wide range of biological processes including development, homeostasis, and disease. Accessible technologies to precisely manipulate signaling have important applications in ...

Happy to share a new preprint from my lab! We characterize the on/off kinetics, light dosage-dependence, and more for a suite of optogenetic signaling activators in zebrafish embryos 💡 www.biorxiv.org/content/10.1...

Become our neighbor!! Check out this amazing opportunity @imbavienna.bsky.social - top-notch research environment with fantastic facilities, and all of that in a thriving international environment in beautiful Vienna!

A big round of 👏👏👏 to our postdoc @idajentoft.bsky.social for being awarded a @hfspo.bsky.social postdoctoral fellowship for her research on #killifish #diapause in our lab! Welcome to the fantastic #HFSP community, Ida!

Really happy to have been awarded an @hfspo.bsky.social fellowship for my postdoc in the @pauligroup.bsky.social @impvienna.bsky.social ! I’m excited to join the HFSP community and for all the opportunities this fellowship brings! 🐠

We are seeking a new colleague to join us at the Vienna BioCenter, specifically at my beloved home institution, IMBA @imbavienna.bsky.social

we value collegiality and a passion for curiosity driven science. Being a great and fun human being also helps!

Last days to get your registration and abstracts submitted for the @embo.org meeting on "RNA meetings Protein Decay" in Vienna (11-14 May 2025). Deadline to register and submit abstracts is April 1st!