Kathrin Garschall

We found no signs of DNA incorporation for
#HEK293 cells ✅ EU only in RNA
@mchatzigeorgiou.bsky.social
#Drosophila wing disc ✅ EU only in RNA
Katherine L. P. Downham & Fergal O'Farrell

Thanks also to @prhsteinmetz.bsky.social for encouraging us to follow the 🐇!

In marine invertebrates 💙, test for DNA incorporation of EU!
#Nematostella ⚠️ EU in RNA+DNA
#Aiptasia ⚠️ EU in DNA
#Ctenophores ✅ EU only in RNA
@ruthstyfhals.bsky.social @pawelburkhardt.bsky.social
#Platynereis ⚠️ EU in RNA+DNA
@leonieadelmann.bsky.social @tessmarraiblelabs.bsky.social

The nascent RNA labelling compound 5-ethynyl uridine (EU) integrates into DNA in some animals - BMC Molecular and Cell Biology BMC Molecular and Cell Biology - The detection of de novo synthesized mRNA transcripts is crucial for understanding the regulation of eukaryotic transcription. Using nucleoside or nucleotide...

A huge thanks to our amazing collaborators from @msarscentre.bsky.social, @unibergen.bsky.social and @univie.ac.at who helped investigate how commonly EU ends up in the wrong macro-molecule. 👏

Check it out at link.springer.com/article/10.1...

Diagram showing ethynyl-uridine incorporation in marine invertebrates, expected to label RNA but unexpectedly also detected in DNA, highlighted with a warning symbol.

So excited to see @malinkjosavik.bsky.social beautiful work out @bmc.springernature.com 🤩! Check it out to see where the RNA-label ✨EU✨ shows up in our favourite sea anemone and how to catch your organism crafting DNA from RNA labelling tools 🧬👀.
#transcription

Molecular and Cell Biology of Symbiosis | Marine Biological Laboratory This is an immersive research-based course designed to teach basic concepts, open research questions, and facilitate state-of-the-art experimental approaches in symbiosis research.

🚨🧪Help us share:
Registration deadline to the MBL #Symbiosis course got extended!
Join us to get practical experience on a diversity of symbiotic organisms at the legendary MBL in Woods Hole.

Promotional image for the MBL's 2025 Molecular and Cell Biology of Symbiosis course, showing a close-up of a cephalopod and event details: July 24 - August 26, 2025, applications due March 12, 2025. Financial assistance available. Includes hashtag #ScienceStartsHere and a logo for the Marine Biological Laboratory.

March 12 is your last chance to apply for the MBL's 2025 Molecular and Cell Biology of Symbiosis course! 🗓️

This immersive, research-based course facilitates state-of-the-art experimental approaches in symbiosis research.

Read more: bit.ly/4ig81fJ
#ScienceStartsHere

Fantastic news! 👏Congrats James!

Preprint alert! 🧪📣 The latest work of the Steinmetz group @prhsteinmetz.bsky.social on the nutritional control of quiescence in Nematostella is out! Congratulations to lead author @eudaldpascual.bsky.social & @ktgarschall.bsky.social 👏 Read the story ⤵️

Schematic summary of Vasa+/Piwi+ cells deepining in quiescence when starved longer.

Thrilled to share our new prepreprint on the nutritional control of #Nematostella Vasa+/Piwi+ cells. Prolonged starvation delays Tor activation & cell cycle re-entry indicating quiescence deepening! tinyurl.com/2k9azd4y
@eudaldpascual.bsky.social @ktgarschall.bsky.social @msarscentre.bsky.social

Thrilled to see #choanoflagellates on the cover of Science Advances🤩. Our latest work "Electrical signaling and coordinated behavior in the closest relative of animals" out now. Link: www.science.org/doi/10.1126/... 👏 @jeffcolgren.bsky.social @msarscentre.bsky.social

Heat stress drives rapid viral and antiviral innate immunity activation in Hexacorallia The cnidarian class Hexacorallia, encompassing stony corals and sea anemones, plays a critical role in marine ecosystems. Coral bleaching, the disruption of the symbiosis between stony corals and zoox...

1/3 I am very excited to tell you about our latest work where we looked not only into sea anemones but also 🪸
We find in #Nematostella that stress induces not immunity, but also viral replication, actually much faster than the immune response! 🧵
www.biorxiv.org/content/10.1...

Happy to share that the Gahan lab will be branching out (or more like returning) to working on Nematostella in the near future. Details will follow but for now if anyone is interested in doing a Postdoc or PhD in 2025 on chromatin in Nematostella drop me a message :)

Group Leader Positions (Researcher I, code 1110) (270380) | University of Bergen Job title: Group Leader Positions (Researcher I, code 1110) (270380), Employer: University of Bergen, Deadline: Sunday, December 15, 2024

At the Michael Sars Centre, 📢 We are hiring Group Leaders! 🌊
Come join our team @UiB to lead innovative research in molecular, cellular and organismal biology using marine/aquatic organisms! ⌛️ Application deadline Dec. 15. Share this exciting opportunity ⤵️
tinyurl.com/4bwn8u3n @embl @EMBRC_EU

Join us at the Symbiosis course!
With @pcleves.bsky.social @scottnichols.bsky.social & others!