Matthias Soller

Complementary expression rather than specialised function for ribosomal paralogs - very interesting finding!

Getting close to a two third majority.

Super cool story - viruses keep translation up by preventing mRNA circularisation!

www.nature.com/articles/s41...

A great historical account of one of the most fascinating and important clusters of genes in animal evolution. The Master Regulators: The Hox. Despite knowing so much about them since the McGinnis 1984 Cell paper, they retain a core mystery that is difficult to explain. Namely: why clustering?

AI reviewers are here — we are not ready Artificial intelligence promises rapid and polite feedback on papers — but we must first review the reviewer.

Artificial intelligence promises rapid and polite feedback on papers — but we must first review the reviewer. This stand first says it all…
A timely World View Colin in our pages by Giorgio Gilestro

🧪 #academicSky
@nature.com

www.nature.com/articles/d41...

We have been receiving excellent protocol papers for this collection. Submission still open!

Queuosine - nostalgic first encounter with RNA and modifications, and my later PhD supervisor Eric Kubli.
www.nature.com/articles/294...

The CNRS is breaking free from the Web of Science From January 1st 2026, the CNRS will cut access to one of the largest commercial bibliometric databases, Clarivate Analytics'

From January 1st 2026, the CNRS will cut access to one of the largest commercial bibliometric databases, Clarivate Analytics' Web of Science, along with the Core Collection and Journal Citation Reports.

Our greetings were from a woodchuck - all flowers cut on top, like if some had used a scissor just below the flower. Didn't make it for review either.

Evolution of taste processing shifts dietary preference - Nature Calcium imaging of taste neurons and the ventral brain provides insight into evolutionary divergence of food choice in Drosophila species, supporting a role of sensorimotor processing in addition to p...

Thrilled to share our new paper!
With @tomtom-auer.bsky.social team, we asked how #evolution reshapes what animals #eat to match their ecological niches. Using pan-neuronal Ca2+ imaging, we show that the changes are in how the brain processes #taste.
Link @nature.com: www.nature.com/articles/s41...

Bold by stress!

Six postdoc positions in two brand new team science projects on mechanistic biology in the overlap area of ageing and sex differences @mrc-lms.bsky.social in London - apply now!

Sorry, I missed your talk! Hope to catch up some other time.

Cool tool! Though it didn't find our interactions. Maybe needs to play in RNA.

Adenine DNA methylation associated with transcriptionally permissive chromatin is widespread across eukaryotes - Nature Genetics Long-read sequencing in 18 unicellular eukaryotes reveals that 6mA is widespread across eukaryotes and is enriched at transcriptionally permissive regions, which are also marked by H3K4me3.

Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9

An advertisement for the project Cryptc consequences of a selfish X chromosome. It shows chromosome mapping indicating many inversions, flies with eye colour phenotypes (wild-type brighter than selfish X), and sections of testes that show ordered (wild-type) or deformed structure (selfish X).

We have a funded NERC PhD studentship!

Selfish X chromosomes are these bizarre things where males carrying the selfish X suffer from imploding testes. Lots to do in this space, especially in evolutionary, stress, and infection biology.

Please share!

#PhDchat #AcademicSky @uniexecec.bsky.social

This work is now officially published
@natsmb.nature.com
with some fun new analyses included in the revised version. Congratulations to all the authors! @connyyu.bsky.social @rappsilber.bsky.social @lrsinn.bsky.social @fjoreilly.bsky.social www.nature.com/articles/s41...

In memory every summer!

Preprint: Bacteria sense virus-induced genome degradation via methylated mononucleotides

tinyurl.com/ch3damp

We show how molecular byproducts released during virus-induced cell exploitation are used as signals to trigger host immunity

Revealed by the amazing Ilya Osterman. See his thread below👇

🦖 Something HUGE just hatched.

Plasmidsaurus now offers RNA sequencing for gene expression analysis:
• As fast as 3 day turnaround
• $50/sample for academia, $80 for industry
• Up to ~10M unique transcript 3’ end reads per sample
• Interactive results

Explore Plasmidsaurus RNA-Seq today.

Evidence for improved DNA repair in long-lived bowhead whale - Nature Analysis of the longest-lived mammal, the bowhead whale, reveals an improved ability to repair DNA breaks, mediated by high levels of cold-inducible RNA-binding protein.  &nbs...

Cold-inducible RNA-binding protein CIRBP: A whales secret to long life?
www.nature.com/articles/s41...

Well represented #EMBO epitranscriptomics 2025

We have a new academic post opening for a Lecture/Senior-Lecturer in Structural Biology @mcf-uom.bsky.social @fbmh-uom.bsky.social @manchester.ac.uk The University of Manchester is ranked among the top Universities worldwide. QS world rankings: 34th (2025)

www.jobs.manchester.ac.uk/Job/JobDetai...

Unlocking the regulatory code of RNA: launching the Human RNome Project - Genome Biology The human RNome, the complete set of RNA molecules in human cells, arises through complex processing and includes diverse molecular species. While research traditionally focuses on four canonical nucl...

Exciting news for the RNA research community!

The Human RNome Project has been launched: a global effort to map all human RNAs and their chemical modifications. Proud to support it and contribute to the article in Genome Biology doi.org/10.1186/s130...
#RNA #bioinformatics #RNAstructure #modomics

Why?
Water companies are paid to deal with waste water, like coffee.
Unbelievable how deteriorated this has become. On the cost of tax payers.

Neuroendocrine control of calcium mobilization in the fruit fly - Nature The peptide hormone Capa is responsible for regulating extracellular fluid Ca2+ levels in the fruit fly Drosophila melanogaster.

Excited to share our paper, led by Naoki Okamoto in our group, just out in Nature!

Neuroendocrine control of calcium mobilization in the fruit fly
www.nature.com/articles/s41...

We “re”-discovered the calcium storage site in “boneless” Drosophila and revealed how calcium mobilization is regulated.

Assessing species-specific neonicotinoid toxicity using cross-species chimeric nicotinic acetylcholine receptors in a Drosophila model - Scientific Reports Scientific Reports - Assessing species-specific neonicotinoid toxicity using cross-species chimeric nicotinic acetylcholine receptors in a Drosophila model

We’ve not given up trying to work out what is killing the bees, with @matthiassoller.bsky.social @annalassota.bsky.social www.nature.com/articles/s41... Assessing species-specific neonicotinoid toxicity using cross-species chimeric nicotinic acetylcholine receptors in a Drosophila model

The catalytic efficiency of METTL16 affects cellular processes by governing the intracellular S-adenosylmethionine setpoint Flaherty et al. demonstrate that the catalytic efficiency of METTL16 regulates expression of MAT2A to determine the intracellular SAM setpoint. Their data indicate that this is required for several SA...

This is a super interesting paper by @conradlab.bsky.social lab on METTL16. They separate METTL16 function on U6 and MAT2A allowing more accurate analysis. Their results cast serious doubt on hundreds of papers claiming METTL16 methylates vast number of mRNAs. www.cell.com/cell-reports...

Enhanced hybridization-proximity labeling discovers protein interactomes of single RNA molecules - Nature Communications Systematic discovery of proteins interacting with low-abundance RNAs is challenging. Here, the authors develop an enhanced HyPro technology to identify proteins associated with compact RNA compartment...

Our paper describing enhanced hybridization-proximity labeling technology is finally out! Enhanced HyPro can identify proteins associated with small RNA compartments and even some individual transcripts, such as pathological C9orf72 transcripts: www.nature.com/articles/s41...

Future thinking.