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@davidpatterson.bsky.social

Chemical biologist. Currently working on spatial omics for 10x Genomics.

74 Followers  |  658 Following  |  3 Posts  |  Joined: 23.10.2023  |  1.7951

Latest posts by davidpatterson.bsky.social on Bluesky

My first time listening to a SCOTUS case directly. Not sure what I expected, but listening to judges help make the case for a given side directly seems weird. I, very naively, assumed they would be hearing and trying to understand the argument versus guide the lawyers to their predetermined outcome.

15.10.2025 16:19 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

The level of kleptocratic corruption in this regime is breathtaking, e.g.:

โ€”Selling off Freddie Mac & Fannie Mae to big banks

โ€”Bribes from ABC & CBS

โ€”TikTok sale to Ellison

โ€”Everything Qatar: the plane gift, the Idaho military base

โ€”Whoever has bribed him by buying his scam meme coins

13.10.2025 04:03 โ€” ๐Ÿ‘ 5020    ๐Ÿ” 1789    ๐Ÿ’ฌ 168    ๐Ÿ“Œ 65

it is incredible to see the extent to which the Sensible Centrists are simply incapable of grasping the very simple and obvious fact that the president's concern with crime is a pretext, and that to deny claims of a sudden epidemic in crime is not to say that crime is nonexistent.

16.08.2025 22:03 โ€” ๐Ÿ‘ 7655    ๐Ÿ” 1113    ๐Ÿ’ฌ 206    ๐Ÿ“Œ 51

Let me try a few:
- GOPpledygook
- GOP Flop
- Repubs Flub
- Sloppy GOP
- Republicans in Ruin
- MAGA in misery

Maybe you can make one catch on. ๐Ÿซก

05.06.2025 04:58 โ€” ๐Ÿ‘ 7    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Big screen. Big science. Stop by Booth #2456 at #AACR25 to see our single cell and spatial solutions like never before ๐Ÿคฉ From sample to insightsโ€”see whatโ€™s possible!

29.04.2025 15:00 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Forcing people to pay $130 for a passport in order to vote is just a Jim Crow poll tax by another name.

It is blatantly unconstitutional.

10.04.2025 21:46 โ€” ๐Ÿ‘ 48495    ๐Ÿ” 12882    ๐Ÿ’ฌ 1477    ๐Ÿ“Œ 433
Preview
Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN Dr. Ardem Patapoutian says he watches โ€œwith deep sadness as the United Statesโ€™ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...

Great article by @nobelprize.bsky.social laureate @ardemp.bskyverified.social outlining the health, economic and national security benefits of US biomedical research, and the devastation of government efforts to destroy our leading edge.

www.cnn.com/2025/04/09/h...

09.04.2025 14:30 โ€” ๐Ÿ‘ 116    ๐Ÿ” 49    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3

an executive order is not a law
an executive order is not a law
an executive order is not a law
an executive order is not a law
an executive order is not a law
an executive order is not a law
an executive order is not a law
an executive order is not a law
an executive order is not a law

28.03.2025 05:43 โ€” ๐Ÿ‘ 30750    ๐Ÿ” 7663    ๐Ÿ’ฌ 459    ๐Ÿ“Œ 322

Harvard Medical School, are you OK with this outcome? Who will speak up for her?

27.03.2025 22:05 โ€” ๐Ÿ‘ 224    ๐Ÿ” 53    ๐Ÿ’ฌ 6    ๐Ÿ“Œ 0
Preview
Reducing batch effects in single cell chromatin accessibility measurements by pooled transposition with MULTI-ATAC Large-scale scATAC-seq experiments are challenging because of their costs, lengthy protocols, and confounding batch effects. Several sample multiplexing technologies aim to address these challenges, b...

Happy to share that the preprint to our new scATAC-seq multiplexing method, MULTI-ATAC, is officially online:
www.biorxiv.org/content/10.1...

20.02.2025 21:48 โ€” ๐Ÿ‘ 6    ๐Ÿ” 3    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1
When the case reached the Supreme Court, the Court held that systems of political patronage like the one established by Thompson violate the First Amendment. Quoting one of its first patronage decisions, the Court reaffirmed that โ€œconditioning public employment on the provision of support for the favored political party โ€˜unquestionably inhibits protected belief and association.โ€™โ€ Doing so โ€œpressures employees to pledge political allegiance to a party with which they prefer not to associate, to work for the election of political candidates they do not support, and to contribute money to be used to further policies with which they do not agree.โ€ It is โ€œtantamount to coerced belief,โ€ something the First Amendment plainly forbids. Nor did it matter that Thompson had not issued a direct order specifying that only Republicans would be hired, because โ€œwhat the First Amendment precludes the government from commanding directly, it also precludes the government from accomplishing indirectly.โ€

When the case reached the Supreme Court, the Court held that systems of political patronage like the one established by Thompson violate the First Amendment. Quoting one of its first patronage decisions, the Court reaffirmed that โ€œconditioning public employment on the provision of support for the favored political party โ€˜unquestionably inhibits protected belief and association.โ€™โ€ Doing so โ€œpressures employees to pledge political allegiance to a party with which they prefer not to associate, to work for the election of political candidates they do not support, and to contribute money to be used to further policies with which they do not agree.โ€ It is โ€œtantamount to coerced belief,โ€ something the First Amendment plainly forbids. Nor did it matter that Thompson had not issued a direct order specifying that only Republicans would be hired, because โ€œwhat the First Amendment precludes the government from commanding directly, it also precludes the government from accomplishing indirectly.โ€

Right now, DOGE is saying that any new hires have to be approved by their office.
In 1980, when IL Governor Thompson said any new hires had to be approved by his office, the Supreme Court said it was unconstitutional politicization of hiring.
What about now?
www.theatlantic.com/ideas/archiv...

15.02.2025 23:03 โ€” ๐Ÿ‘ 1249    ๐Ÿ” 365    ๐Ÿ’ฌ 23    ๐Ÿ“Œ 6

Tapping this sign again. Gonna tap it every week.

Forget your savvy & your cleverness & your 3D chess. Just skip to the end, where you *fight*.

15.02.2025 19:16 โ€” ๐Ÿ‘ 439    ๐Ÿ” 97    ๐Ÿ’ฌ 7    ๐Ÿ“Œ 2

This totally misses a major category of college student facial hair. Somewhere 3 to 30 days post shave. Not quite a beard and never really clean shaven.

10.01.2025 22:57 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
The image is from a "Transparency Center" document and lists guidelines regarding acceptable and prohibited content for insults. It mentions:

1. Insults about:

Character, such as cowardice, dishonesty, criminality, and sexual promiscuity or immorality.

Mental characteristics, including but not limited to accusations of stupidity, intellectual capacity, and mental illness, as well as unsupported comparisons among politically correct (PC) groups based on inherent intellectual traits.

2. Highlighted section:

The document allows allegations of mental illness or abnormality when tied to gender or sexual orientation, referencing political and religious discourse about transgenderism and homosexuality. It also acknowledges the non-serious use of terms like "weird."

The image is from a "Transparency Center" document and lists guidelines regarding acceptable and prohibited content for insults. It mentions: 1. Insults about: Character, such as cowardice, dishonesty, criminality, and sexual promiscuity or immorality. Mental characteristics, including but not limited to accusations of stupidity, intellectual capacity, and mental illness, as well as unsupported comparisons among politically correct (PC) groups based on inherent intellectual traits. 2. Highlighted section: The document allows allegations of mental illness or abnormality when tied to gender or sexual orientation, referencing political and religious discourse about transgenderism and homosexuality. It also acknowledges the non-serious use of terms like "weird."

Meta literally created a LGBTQ exception for calling someone mentally ill as an insult. You can't do it for any other group except LGBTQ people.

08.01.2025 01:51 โ€” ๐Ÿ‘ 15427    ๐Ÿ” 6356    ๐Ÿ’ฌ 651    ๐Ÿ“Œ 1608

I'm endlessly kind of baffled by the lack of urgency on housing California. This is the state's number one problemโ€”a crisis so bad that's imperiling national Democratic ambitions. And all we can pass are heavily compromised bills that take effect in like five years, if ever.

10.12.2024 01:09 โ€” ๐Ÿ‘ 824    ๐Ÿ” 125    ๐Ÿ’ฌ 37    ๐Ÿ“Œ 16
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New paper out in @ScienceMagazine! In 8 studies (multiple platforms, methods, time periods) we find: misinformation evokes more outrage than trustworthy news, when it does it's shared more + ppl are less likely to read before sharing. w/ @killianmcl1 @Klonick @mollycrockett ๐Ÿงต๐Ÿ‘‡

28.11.2024 19:06 โ€” ๐Ÿ‘ 3560    ๐Ÿ” 1165    ๐Ÿ’ฌ 128    ๐Ÿ“Œ 139

@davidpatterson is following 20 prominent accounts