Edna Cukierman - Tumor Microenvironment's Avatar

Edna Cukierman - Tumor Microenvironment

@tme-caf-ecm.bsky.social

Fibroblastic cells + ECM = functional unit.
I study these #TumorMicroenvironment units in #PancreaticCancer interception, tumorigenesis, immunosuppression, stroma function evaluation, & drug responses. https://www.foxchase.org/edna-cukierman
My posts!

2,606 Followers  |  672 Following  |  85 Posts  |  Joined: 14.12.2023  |  2.3635

Latest posts by tme-caf-ecm.bsky.social on Bluesky

Post image

x.com/nobelprize/s...
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.” @thenobelpeaceprize.bsky.social

06.10.2025 09:58 — 👍 2    🔁 0    💬 0    📌 0
From left to right, Elda, myself, and  Zobeida smiling with the AACR Pancreatic Cancer Research meeting hall in the background

From left to right, Elda, myself, and Zobeida smiling with the AACR Pancreatic Cancer Research meeting hall in the background

#AACRPan25 #PancreaticCancer research
@theaacr.bsky.social

#ItTakesAVillage

I feel very lucky to have such amazing friends and colleagues!!
#EldaGrabocka & @zcmlab.bsky.social

#WomanInSTEM

01.10.2025 22:21 — 👍 18    🔁 2    💬 1    📌 0
Preview
Yan Leyfman: γδ T Cells as Scalable “Off-the-Shelf” Therapy for Solid Tumors - OncoDaily Yan Leyfman: γδ T Cells as Scalable “Off-the-Shelf” Therapy for Solid Tumors / Adnan Moinuddin, Ali A. Ashkar, Allyson E. Moore, Ana L. Portilloa, cancer,

γδ T Cells as Scalable “Off-the-Shelf” Therapy for Solid Tumors - Yan Leyfman

@yleyfman.bsky.social

oncodaily.com/voices/yan-l...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #SolidTumors

01.10.2025 20:42 — 👍 5    🔁 1    💬 0    📌 0
Post image Post image Post image

This is how to kick a talk out of the game park! A true #HomeRunTalk by @jayeperview.bsky.social at the selected talks from posters closing the #AACRPan25 @theaacr.bsky.social meeting

First talk out of her own lab
@thegardinerlab.bsky.social
#Proudisima to have played a small role 😎💜

01.10.2025 15:15 — 👍 16    🔁 4    💬 1    📌 0
Post image

Next up in our Article Showcase is a featured selection from Edna Cukierman, Senior Editor of Tumor Biology: “Targeting Pancreatic Cancer Cell Stemness by Blocking Fibronectin-Binding Integrins on Cancer-Associated Fibroblasts” buff.ly/v2ICc8M @tme-caf-ecm.bsky.social

01.10.2025 13:08 — 👍 2    🔁 1    💬 1    📌 0
Post image

#AACRPan25 @theaacr.bsky.social
Being a #ProudisimaPI & the opportunity of becoming a #ProudisimaColleague
is the best feeling ever!

#pancreaticcancer #foxchasecancercenter @jayeperview.bsky.social @debvendramini.bsky.social @saumyamarumdphd.bsky.social #AlexDolskii @brookepereira.bsky.social

01.10.2025 03:05 — 👍 14    🔁 2    💬 0    📌 0

Looking forward to day 2 (chaired by yours truly 😎)
#AACRPan25 #PancreaticCancer
@theaacr.bsky.social

29.09.2025 10:30 — 👍 2    🔁 0    💬 0    📌 0
Post image Post image Post image Post image

The first day of the @theaacr.bsky.social #AACRPan25 meeting in Boston started with a bang!!! It was all about #PancreaticCancer Interception

and what a list of speakers!
A few pics of #Day1 💜

29.09.2025 10:07 — 👍 7    🔁 0    💬 1    📌 0
Post image

Read the abstracts from @theaacr.bsky.social Special Conference in Cancer Research: Advances in Pancreatic Cancer Research here in the September 15 issue of Cancer Research: buff.ly/ncicLEB

#AACRpan25

28.09.2025 15:22 — 👍 2    🔁 1    💬 0    📌 0

On my way to #AACRPan25
#PancreaticCancer 💜

28.09.2025 14:58 — 👍 1    🔁 0    💬 0    📌 0

I am so lucky to count with the amazing #oneandonly @rolanddunbrack.bsky.social as my colleague and thrilled to count him as my dear friend!!!
#congratulations!!!

06.09.2025 15:30 — 👍 4    🔁 2    💬 1    📌 0
Preview
a breaking news sign is displayed on a blue and red background ALT: a breaking news sign is displayed on a blue and red background

#ExtraExtra the amazing @saumyamarumdphd.bsky.social just joined our #GIMedicalOncology and the Cancer Signaling & Microenvironment Program as our newest #AssistantProfessor at #FoxChaseCancerCenter #PancreaticCancer #TumorMicroenvironment

We wish you the #BestofLuck!!!!! 💜💜💜

06.09.2025 15:27 — 👍 5    🔁 0    💬 0    📌 1
The lab-team and significant others

The lab-team and significant others

Jaye showing off her Friends of Fox Chase Cancer Center new jacket

Jaye showing off her Friends of Fox Chase Cancer Center new jacket

#ProudisimaPI

Traditional #CukiermanLab ‘s summer falafel & empanadas day; at yours truly’s house!

it was #bittersweet; I am enormously happy to be so sad… 🥹

We were wishing #bestofluck to the amazing @jayeperview.bsky.social who is opening @thegardeningbard.bsky.social at #Tufts in September!!

17.08.2025 13:39 — 👍 14    🔁 0    💬 0    📌 0
Post image

The amazing @ptorresayuso.bsky.social from #FoxChaseCancerCenter and #TempleUniversity presenting his exciting research at the @ncicapit.bsky.social summit

24.07.2025 19:33 — 👍 7    🔁 2    💬 0    📌 0
Preview
a poster that says out of this world ALT: a poster that says out of this world

The 2025 Annual @ncicapit.bsky.social Summit is #Outofthisworld good!!! The plenary speaker #EvaSzabo, the keynote presentation by #RafiAhmed followed by AI guru #ChanghueiYang & #force ‘s #SueFredman & panelist for #EmergingTechnologies lead by the amazing #ShannonHughes were extraordinary!!!

24.07.2025 18:59 — 👍 1    🔁 1    💬 0    📌 0

@jayeperview.bsky.social will make me the most (ex) #ProudisimaPI this fall as she opens her lab at #Tufts
She is not only an amazing researcher but an innovative #ScienceCommunicator so everyone should follow her 💜💚

24.07.2025 10:11 — 👍 11    🔁 1    💬 0    📌 0

It is a lab-mate’s birthday, but thank you!!! the lab will be 23 in September 🙃 💜

22.07.2025 19:50 — 👍 1    🔁 0    💬 0    📌 0
Post image

#LabBirthdays (note the tomatoes pointed by the red arrow; favorite of the birthday lab mate 😂)

22.07.2025 19:44 — 👍 4    🔁 0    💬 1    📌 0
Post image

Great news! The AACR journals are now on BlueSky! Be sure to follow @aacrjournals.bsky.social!! #FollowFriday

18.07.2025 19:59 — 👍 39    🔁 12    💬 0    📌 0
Preview
AACR Special Conference in Cancer Research: Advances in Pancreatic Cancer Research—Emerging Science Driving Transformative Solutions Meeting overview details for AACR Special Conference in Cancer Research: Advances in Pancreatic Cancer Research - Emerging Science Driving Transformative Solutions

@theaacr.bsky.social Register by August 18 to get the lowest rates for the AACR Conference on Advances in #PancreaticCancer Research (Sept 28-Oct 1; Boston), chaired by #AndrewAguirre, #SusanTsai, #DavidTuveson, #LauraDeLongWood, and yours truly.
brnw.ch/21wUg3J
#AACRpan25

19.07.2025 10:59 — 👍 5    🔁 0    💬 0    📌 0
Preview
MatriCom – the extracellular matrix reloaded The extracellular matrix (ECM) is made up of hundreds of proteins, including structural core ‘matrisome’ proteins, factors that associate with and regulate ECM architecture and dynamics, and ECM recep...

And what about *they also made a commentary of our work*??? I really really love JCS!!!
journals.biologists.com/jcs/article/...

12.07.2025 15:48 — 👍 10    🔁 4    💬 1    📌 0

I wish I was there!!!

12.07.2025 15:53 — 👍 1    🔁 0    💬 1    📌 0

To honor her, after her passing from #PancreaticCancer, I decided to focus my lab on its #TME 💔

24.06.2025 10:29 — 👍 4    🔁 0    💬 0    📌 0
Patricia Keely’s obituary foto with birth and death dates

Patricia Keely’s obituary foto with birth and death dates

8 years ago today we lost our dearest #PatKeely who revolutionized the #TME #ECM field by introducing us to the diagnostic/prognostic tumor-associated collagen signatures #TACs

We miss her enormously everyday ❤️‍🩹

24.06.2025 10:10 — 👍 15    🔁 3    💬 1    📌 1
A Milestone for Our Mission: Fox Chase Cancer Center Reaffirms National Leadership with Renewal of Prestigious NCI Grant

😎
www.foxchase.org/news/milesto...

18.06.2025 14:40 — 👍 1    🔁 0    💬 0    📌 0
JCI - Metastatic tumor growth in steatotic liver is promoted by HAS2-mediated fibrotic tumor microenvironment

www.jci.org/articles/vie... Very important discovery on metastatic #CRC due to HA and collagen-based liver fibrosis generated by hepatic #CAFECMUnits

13.06.2025 05:05 — 👍 2    🔁 0    💬 0    📌 0
Preview
AACR Special Conference in Cancer Research: Advances in Pancreatic Cancer Research - Emerging Science Driving Transformative Solutions Meeting overview details for AACR Special Conference in Cancer Research: Advances in Pancreatic Cancer Research - Emerging Science Driving Transformative Solutions

www.aacr.org/meeting/aacr...
Abstracts and award applications are due July 15. See you in Boston Sep 28 to Oct 1. @theaacr.bsky.social #PancreaticCancer #2025

02.06.2025 13:24 — 👍 4    🔁 2    💬 0    📌 0
Interview with  Ashani Weeraratna
YouTube video by CSHL Leading Strand Interview with Ashani Weeraratna

"No tumor is an island" and "oncology recapitulates embryology" - a fascinating conversation with the incredible @ashi-w.bsky.social at the CSHL symposium on aging.

We talk about how cancer rates increase with age, the T(I!)ME, and the role of Wnt signaling www.youtube.com/watch?v=_Txf...

30.05.2025 00:01 — 👍 46    🔁 10    💬 2    📌 0

Thank you my queen!! 💜💜 Inspired by you and other leaders, we are so keen to learn more about tissue-level tumor suppression alongside our amazing pancreatic cancer research community ✨

02.05.2025 18:44 — 👍 3    🔁 1    💬 0    📌 0
Stromal KITL/SCF Maintains Pancreas Tissue Homeostasis and Restrains Tumor Progression Normal pancreatic mesenchyme expresses stem cell factor (KITL), which is lost in the cancer-associated fibroblast state during tumorigenesis and restrains pancreatic inflammation, epithelial identity,...

Check out this seminal study @theaacr.bsky.social by the one and only @marasherman.bsky.social

aacrjournals.org/cancerdiscov...

& the commentary about its importance to gain understanding on the inherent tumor-suppressive #PancreaticCancer #TME (by yours truly)

aacrjournals.org/cancerdiscov...

02.05.2025 18:01 — 👍 22    🔁 7    💬 1    📌 0

@tme-caf-ecm is following 20 prominent accounts