Daniel Jones's Avatar

Daniel Jones

@dcjones.bsky.social

Computational biologist at Fred Hutchinson Cancer Center (See my work here: https://dcjones.github.io/). I also post about baking, books, and Seattle politics.

841 Followers  |  407 Following  |  130 Posts  |  Joined: 15.11.2023  |  2.0486

Latest posts by dcjones.bsky.social on Bluesky


Super disappointed in Lin. This area right around the stadium is not being used for industry, there are only upsides to allowing housing.

20.02.2026 16:40 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Photo of Pioneer Square in 1910 with streetcar tracks and people walking in the streets.

Photo of Pioneer Square in 1910 with streetcar tracks and people walking in the streets.

Historic character means pedestrianized streets with trolleys everywhere, I don't make the rules!

18.02.2026 18:12 โ€” ๐Ÿ‘ 6    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Blurry photo of a small house listed for $1,090,000.

Blurry photo of a small house listed for $1,090,000.

Seattle housing is so cooked ๐Ÿ˜ฉ

12.02.2026 23:36 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Gov. Bob Ferguson to meet with the NBA commissioner on Thursday Gov. Bob Ferguson is meeting with NBA Commissioner Adam Silver on Thursday, although neither the agenda nor context for the meeting are yet known.

Katie Wilson bringing back the SuperSonics would be the funniest timeline, so I choose to believe www.seattletimes.com/sports/sonic...

05.02.2026 18:50 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
A plot showing BTC falling over the last several months.

A plot showing BTC falling over the last several months.

Turns out you don't actually need a central bank to debase your currency. Such innovation!

05.02.2026 17:43 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Yeah I get that she's very policy focused and maybe not inclined to do nonstop short form videos, but she's not bad at it and should do more of it anyway imo

22.01.2026 16:54 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Was thinking about that when I saw this take. Wilson is very much not talking every day, and I kind of wish she would. bsky.app/profile/lowr...

22.01.2026 16:13 โ€” ๐Ÿ‘ 8    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

One the one hand, hyperinflation would be a generational catastrophe, on the other, us I-bond holders will able to buy gas and ammo in the wasteland

12.01.2026 02:42 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I feel like a lot of these guys really just want to be podcasters and are annoyed at having any other responsibilities.

05.01.2026 23:47 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Glad we won't have to hear from this guy anymore soon bsky.app/profile/kuow...

05.01.2026 23:40 โ€” ๐Ÿ‘ 10    ๐Ÿ” 3    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Please no one tell Sacks that Seattle exists

01.01.2026 21:44 โ€” ๐Ÿ‘ 8    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

This was super interesting! I wish OUP didn't charge $120 for his book ๐Ÿ˜ญ

20.12.2025 19:07 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

This is such a pure distillation of the city as a shopping destination view that the times loves to publish

20.12.2025 17:23 โ€” ๐Ÿ‘ 18    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Preview
How Regulation by Litigation Strangled American Abundance Environmentalists aren't blocking housing. Wealthy homeowners are.

"We often blame bureaucrats or red tape for the countryโ€™s paralysis. But the fault lies less in the rules than in who has the resources to weaponize them."
open.substack.com/pub/data4dem...

20.12.2025 16:53 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Release Version 3.1.0 ยท dcjones/proseg This release fixes a serious bug affecting segmentation quality, and introduces a lot of optimizations. It's recommended that you update to this version as soon as possible, particularly if you are...

I'd strongly recommend updating, particularly if you're segmenting Visium HD or other whole-ish transcriptome data.

github.com/dcjones/pros...

19.12.2025 18:02 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I went all out optimizing proseg this week, and after many rounds of profiling and tinkering, the new release is as much as 1.5-4x faster and reduces memory usage by around 10%.

More importantly, I discovered and fixed a subtle bug that reduced segmentation accuracy for large gene panels!

19.12.2025 18:02 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Post image

tfw the guy who made this chart is going to be in charge of the fed

11.12.2025 16:11 โ€” ๐Ÿ‘ 385    ๐Ÿ” 57    ๐Ÿ’ฌ 23    ๐Ÿ“Œ 8
Preview
Good Neighbor policy - Wikipedia

Feel like pure shit just want her back
en.wikipedia.org/wiki/Good_Ne...

10.12.2025 19:19 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Your posts (plus my sister in law working at modular) have really piqued my mojo interest!

09.12.2025 16:51 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

It'll get fixed in a decade or so, like the "University Street" station.

09.12.2025 00:28 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Why Burn? - The Burn Book ๐Ÿ”ฅ

I'm somehow just discovering that there's pretty compelling deep learning framework being built in rust burn.dev/books/burn/m...

07.12.2025 17:50 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
How to Make Prosthetic Arm for Handless People. Korean Artificial Body Part Making Company
YouTube video by All process of world How to Make Prosthetic Arm for Handless People. Korean Artificial Body Part Making Company

We're in a golden age of How Its Made style content on YouTube these days. One of my faves is the Korean channel "All Process of World" youtu.be/GE29Df9q7cU

07.12.2025 16:23 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Congratulations to Seattle's Sound Transit, America's fastest-growing train network, which is opening an 8-mile, 3-station extension to Federal Way today!

This is the system's 4th new segment opened in less than 2 years, continually pushing ridership up to new record highs!

06.12.2025 20:56 โ€” ๐Ÿ‘ 406    ๐Ÿ” 46    ๐Ÿ’ฌ 6    ๐Ÿ“Œ 11
Preview
Episode 103: Fire Safety in Multifamily Housing with Alex Horowitz (Incentives Series pt. 6) Explore why multifamily homes are often safer from fires than single-family housing, as Alex Horowitz shares research on building age, fire risk, and single-stair safety in our Incentives Series.

Pew's main findings:
- Newer multifamily is safer than older multifamily
- Newer multifamily is safer than newer single-family
- Single-stair multifamily buildings are as safe as buildings with two stairwells

www.lewis.ucla.edu/2025/12/03/1...

03.12.2025 17:44 โ€” ๐Ÿ‘ 80    ๐Ÿ” 20    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 9

2020 me: 64GB should be enough for my workstation

2025 me: hmm should I upgrade my ram or pay rent this month?

03.12.2025 21:05 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Micron to exit consumer memory business amid global supply shortage Memory chipmaker Micron Technology said on Wednesday it will exit its consumer business, as it doubles down on advanced memory chips used in artificial intelligence data centers amid a global supply s...

I'm never going to be able to afford memory again. Might just pivot all my work towards probabilistic data structures and online stats.
www.reuters.com/business/mic...

03.12.2025 19:25 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

I don't understand what the passageway stairs lead to. I guess doors will be figured out later?

02.12.2025 00:40 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

I will vote for any dem promising another Master and Commander film

25.11.2025 17:05 โ€” ๐Ÿ‘ 13    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Welcome back to the platform for people who actually read books!

25.11.2025 16:59 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

It's gotta be "The Black Jacobins". An incredibly gripping narrative of a neglected and consequential history.

19.11.2025 23:39 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@dcjones is following 20 prominent accounts