@microbialcell.bsky.social
Microbial Cell is an independent, open-access journal (Austria) for microbial and general cell biology and signaling. By scientists for scientists. 5-year IF 5.3 (2024); CiteScore 6.9 (2024)
Alternative splicing drives a dynamic transcriptomic response during A. castellanii programmed cell death: G418-induced PCD in Acanthamoeba castellanii triggers extensive RNA-seq changes with spikes in pathways tied to cell cycle, proteolysis, and RNA splicing.
microbialcell.com/researcharti...
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#AnkylosingSpondylitis #Microbiome #Autoimmunity #GutJointAxis
New in @microbialcell.bsky.social: comprehensive review on the gut-joint axis in ankylosing spondylitis. Dysbiosis, IL-23/17 pathway, HLA-B27 misfolding, leaky gut, microbial mimicry - potential targets for future microbiota-based therapies. Must-read for scientists and patients! Link below
26.08.2025 06:18 — 👍 0 🔁 0 💬 1 📌 0Disruption of sit1 alters germination, slows growth, reduces virulence, and triggers compensatory iron-uptake genes (FRE, FET4, FET3), revealing intertwined iron-acquisition pathways in mucormycosis. Important insights for antifungal strategies.
14.08.2025 19:25 — 👍 0 🔁 0 💬 0 📌 0
"Role of the putative sit1 gene in normal germination of spores and virulence of the Mucor lusitanicus" by Vágó et al. explores how sit1, a siderophore transporter, is crucial for proper spore germination and full virulence in Mucor lusitanicus.
Read more: shorturl.at/cmD5W
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The study links specific microbial genera - like Luteibacter & Chryseobacterium - to survival risk and introduces an IMTMEindex that more accurately predicts 1-, 3- & 5-year overall survival.
Potential new tool for prognosis & guiding immunotherapy.
New in @microbialcell.bsky.social 🧬
Zhao et al. integrate tumor microenvironment (TME) and intratumoral microbiome data from 478 lung adenocarcinoma patients to build a TMEindex prognostic model.
DOI: 10.15698/mic2025.08.855
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