Thomas Weimbs, PhD

Congratulations to @melinamessing.bsky.social for receiving this prestigious award to support her research on polycystic kidney disease in my lab. And many thanks to the @pkdfoundation.bsky.social and @asnkidney.bsky.social for the support!

Congratulations to @melinamessing.bsky.social for receiving this prestigious award to support her research on polycystic kidney disease in my lab. And many thanks to the @pkdfoundation.bsky.social and @asnkidney.bsky.social for the support!

Congratulations to @melinamessing.bsky.social for receiving the 2025 Jared J. Grantham Research Fellowship Award to study "Immune Mechanisms Underlying Efficacy of Ketogenic Metabolic Therapy in Polycystic Kidney Disease" in my laboratory.

Details here:
www.kidneycure.org/pages/qa.asp...

It has already been shown in animal studies how BHB improves glomerular structure and function. That part isn’t a mystery anymore 😀

Remission of chronic kidney disease is possible with ketogenic metabolic therapy.
Remission? Yes, remission!
2 year follow-up study in diabetic nephropathy just published.
doi.org/10.3389/fnut...

Ketogenic diets in chronic kidney disease patients: a review for skeptics by skeptics - Journal of Nephrology Over the last few decades, there has been growing interest in the use of ketogenic diets, mainly as a weight loss strategy. Obesity and diabetes are major risk factors for kidney disease, and obese pa...

Excellent article summarizing the state of knowledge on ketogenic metabolic therapy for CKD and ADPKD.
--> Every nephrology professional should be aware of this
link.springer.com/article/10.1...

Please forward to your Spanish-speaking friends & family with polycystic kidney disease

If anyone happens to be in Bangkok on Thursday, you are welcome to join my seminar: "Disease-Modifying Therapy of Polycystic Kidney Disease with Nutrition and Lifestyle Interventions"

“Plant-based and ketogenic diets as diverging paths to address cancer”: a commentary concerning the supposed superiority of a plant-based diet A Commentary on Plant-Based and Ketogenic Diets as Diverging Paths to Address Cancer: A Review by Shah AU and Iyengar NM. JAMA Oncol 2022 Aug 1;8(8):1201–8. doi: 10.1001/jamaoncol.2022.1769.

"...all foods can be shown to both cause and prevent cancer"

Love this commentary pointing out how a lot of the nutrition "science" literature is complete crap. That's how we ended up with generations of dietitians and MDs learning things backwards!
www.degruyter.com/document/doi...

Curious about how people with ADPKD can improve their health in a nutrition & lifestyle program?
Video just posted...

Impressive outcomes with ketogenic therapy for an "untreatable" form of brain cancer
www.frontiersin.org/journals/nut...

Therapeutic Potential of Ketogenic Interventions for Autosomal-Dominant Polycystic Kidney Disease: A Systematic Review Background: Recent findings have highlighted that abnormal energy metabolism is a key feature of autosomal-dominant polycystic kidney disease (ADPKD). Emerging evidence suggests that nutritional ketos...

"Therapeutic Potential of Ketogenic Interventions for Autosomal-Dominant Polycystic Kidney Disease: A Systematic Review"
--> Bottom line: Only beneficial outcomes
--> When does it become unethical to withhold info on this alternative from patients?

www.mdpi.com/2072-6643/17...

Ketogenic therapy in chronic kidney disease, stage 3-4
~54 weeks
-> Reduced BMI, HbA1c
-> Improved kidney function (creatinine, BUN)
-> Deprescription of diabetic and BP medication
-> No safety concerns
journalofmetabolichealth.org/index.php/jm...

YouTube video by Low Carb Down Under Dr. Alok Gupta - 'The Role of Ketogenic Diet in Polycystic Kidney Disease (ADPKD)'

Ketogenic Diet for Polycystic Kidney Disease?
What is the evidence? Excellent talk by Australian nephrologist Dr. Alok Gupta.
youtu.be/37Ov8qM-9Co

Discussion about the Ren-Nu nutrition & lifestyle program for people with polycystic kidney disease.
How to get started?

YouTube video by Santa Barbara Nutrients PKD-Free Babies. How?

How the PKD-Free Alliance helps families with polycystic kidney disease to conceive PKD-free babies.
youtu.be/SOdkBI1M7u8

If anyone still believes in protein restriction for kidney disease, take a look at this article.
www.scielo.br/j/jbn/a/MDWX...
@kidneyboy.bsky.social @hswapnil.medsky.social

The English Version: My dad’s incredible journey to improving and maintaining kidney function—after transplant! He implemented KMT post-transplant to support his health. His story challenges the norm and shows the power of nutrition.

Yes, nutrition matters, even post-transplant!

YouTube video by Santa Barbara Nutrients Ketogenic Diet After Kidney Transplantation. What Happened?

Ketogenic lifestyle AFTER kidney transplantation to help maintain kidney function?

Find out what happened to Manfred, who has polycystic kidney disease:
youtu.be/o_3oXym5-pw

Important study!
A multimodal telemedicine intervention not only greatly improves the health of participants but also saves a self-insured company a lot of money
www.frontiersin.org/journals/nut...

My dad’s incredible journey to improving and maintaining kidney function—after transplant! He has PKD and implemented ketogenic metabolic therapy post-transplant to support his health. His story challenges the norm and shows the power of nutrition.

Yes, nutrition matters, even post-transplant!

Efficacy of Low-Carbohydrate Diets Versus Low-Fat Diets in Glycemic Control Among Patients With Type 2 Diabetes: A Systematic Review This systematic review evaluates the comparative efficacy of low-carbohydrate diets (LCDs) versus low-fat diets (LFDs) in improving glycemic control, weight management, and lipid profiles in individua...

Low-carb diets win against low-fat diets (except in most important measure):
- reduce HbA1c, fasting glucose, and triglycerides 💪
- superior weight loss 💪
- increased HDL 💪
Big problem: reductions in diabetes medication!
--> No money to be made 😭

doi.org/10.7759/cure...

YouTube video by Santa Barbara Nutrients Ketogene Diät nach der Nierentransplantation? Was passiert?

Ketogenic diet AFTER kidney transplantation. Wait, what? Why?
Manfred has polycystic kidney disease and implemented ketogenic metabolic therapy AFTER transplantation to maintain his renal function.
In German. English version coming up, stay tuned.
youtu.be/5OTUbvjh7ng

I am thrilled to work even more closely with Dr. Shigeo Horie!

Type-2 innate signals are dispensable for skeletal muscle regeneration and pathology linked to Duchenne muscular dystrophy | EMBO reports imageimageContrary to prior data, this study shows that neither eosinophils nor STAT6-mediated IL-4/IL-13 signaling contribute significantly to muscle repair after acute injury or in Duchenne muscular...

New paper alert! 🚨 Not what we expected.

In @emboreports.org, we show eosinophils & STAT6 have a negligible role in muscle regeneration & DMD—contrary to prior research.

Negative data matters. It moves science forward. 💡🔬
www.embopress.org/doi/full/10....

YouTube video by Santa Barbara Nutrients Preview of Ren-Nu Program Launch

The Ren-Nu renal nutrition program for individuals with POLYCYSTIC KIDNEY DISEASE will soon be re-launched.
Brief discussion and preview with @melinamessing.bsky.social and @weimbs.bsky.social

youtu.be/XmCR05SGdgo

YouTube video by Santa Barbara Nutrients NightmareRH came out with polycystic kidney disease and did something about it

@weimbs.bsky.social talks with NightmareRH about his journey with polycystic kidney disease (ADPKD). Chris was diagnosed without a family history and told that there is nothing he could do, and that he would eventually need to be on dialysis and require a kidney transplant.
--> youtu.be/Vlxl7ZmZPSA

Useful grocery shopping list for people with mild to moderate kidney disease (and other Homo sapiens who want to avoid kidney disease)
- Low Carb (sugars, starch)
- Low Oxalate
- Whole Foods Only
- No Ultra-Processed Foods
--> Download here:
santabarbaranutrients.myshopify.com/pages/shoppi...

Agreed. It's time to stop the protein-restriction nonsense in early CKD. First, do no harm!

If a compelling, long-term RCT demonstrates a clear benefit of protein-restriction, we can talk. The burden of proof is on the intervention. The proof is missing, and has always been missing.

Santa Barbara Nutrients Appoints Dr. Richard J. Johnson to Advisory Board SANTA BARBARA, CA, UNITED STATES, January 22, 2025 Santa Barbara Nutrients, Inc., a leader in developing medical foods and nutritional programs for kidney health, is pleased to announce the appointmen...

I am excited to welcome Dr. Richard Johnson on Santa Barbara Nutrients' advisory board! Dr. Johnson is one of the most influential nephrologists of our time, and a leader in research on metabolism and kidney disease.
News Release:
santabarbaranutrients.com/blogs/news/s...