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WilluhnLab

@willuhnlab.bsky.social

A bunch of passionate neuronerds studying the brain origins of reinforcement learning and compulsive behavior at the Netherlands Institute for Neuroscience. Dopamine, serotonin, basal ganglia, PFC, DBS. https://nin.nl/research/researchgroups/willuhn-group/

414 Followers  |  242 Following  |  20 Posts  |  Joined: 18.11.2024  |  2.1763

Latest posts by willuhnlab.bsky.social on Bluesky

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The CNRS is breaking free from the Web of Science From January 1st 2026, the CNRS will cut access to one of the largest commercial bibliometric databases, Clarivate Analytics'

From January 1st 2026, the CNRS will cut access to one of the largest commercial bibliometric databases, Clarivate Analytics' Web of Science, along with the Core Collection and Journal Citation Reports.

01.12.2025 11:04 β€” πŸ‘ 81    πŸ” 63    πŸ’¬ 0    πŸ“Œ 25
Scientific Reports - Wikipedia

Yikes! Take a look at the β€œControversy” section on the Wikipedia page for Scientific Reports. The supposedly β€œpeer-reviewed,” open-access mega-journal from Nature Portfolio has been dogged by serious issues for years. en.wikipedia.org/wiki/Scienti...

27.11.2025 12:28 β€” πŸ‘ 14    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0
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Scientists Pinpoint the Moment of Decision in the Rat Brain Simons Collaboration on the Global Brain researchers found a synchronized shift in neural activity that signals the moment when animals commit to a decision.

A new study led by Simons Collaboration on the Global Brain investigator @carlosbrody.bsky.social tracked decision-making in rats to pinpoint the precise moment the animals commit to a decision: https://www.simonsfoundation.org/scientists-pinpoint-the-moment-of-decision-in-the-rat-brain/ #science

26.11.2025 19:11 β€” πŸ‘ 7    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Harnessing the muscle of one of the world’s fastest supercomputers, researchers at the @alleninstitute.org and their collaborators have built one of the largest and most detailed biophysically realistic brain simulations of an animal ever!

🐁 See the #MouseBrain simulation: https://bit.ly/47TFf2e

21.11.2025 23:33 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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πŸŽ‰ New in #NeurIPS2025, we present β€œCross-Modal Representational Knowledge Distillation for Enhanced Spike-Informed LFP Modeling”.

We show that high-fidelity spike transformer models can teach LFP models to substantially enhance LFP decoding. #BCI

πŸ‘ Eray Erturk
🧡 Paper, Code ⬇️

25.11.2025 20:15 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Come on Konrad, why do you cave so easily? Here, let me try it for you:
1. Spikes are (to good approximation) the only events that matter.
2. Extracellular fields are one way by which spikes interact with each other.
1/2

21.11.2025 15:51 β€” πŸ‘ 33    πŸ” 9    πŸ’¬ 4    πŸ“Œ 1
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Vacancy alert! @vuamsterdam.bsky.social , @uva.nl, and @amsterdamumc.bsky.social are seeking talent for research positions in neuroscience. Explore all vacancies within the Amsterdam Neuroscience Network and apply now (scroll down to the bottom of our homepage ⬇️) www.amsterdamumc.org/en/research/...

24.11.2025 12:11 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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EastBio: Too sweet: how early life sugar consumption shapes brain and behaviour at University of Aberdeen on FindAPhD.com PhD Project - EastBio: Too sweet: how early life sugar consumption shapes brain and behaviour at University of Aberdeen , listed on FindAPhD.com

Possibility for a Eastbio funded PhD in my group at the @rowettinstitute.bsky.social @uniofaberdeen.bsky.social.
This is a highly competitive process: applicants should hold a 1st BSc Honours or 2:1 MSc degree in neuroscience.
A single applicant per project will be interviewed.
shorturl.at/rd669

19.11.2025 18:02 β€” πŸ‘ 5    πŸ” 6    πŸ’¬ 1    πŸ“Œ 2
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Superior Colliculus Projections Drive Dopamine Neuron Activity and Movement But Not Value To navigate dynamic environments, animals must rapidly integrate sensory information and respond appropriately to gather rewards and avoid threats. It is well established that dopamine (DA) neurons in...

So stoked to have our image on the cover of this week's issue of Journal of Neuroscience!! @sfnjournals.bsky.social #JNeurosci #SfN25. Check out the final version of the paper here www.jneurosci.org/content/45/4...

19.11.2025 18:15 β€” πŸ‘ 101    πŸ” 15    πŸ’¬ 3    πŸ“Œ 0

I have so many issues with this podcast with @earlkmiller.bsky.social . I think that this podcast nicely shows why I have trouble with such approaches. Lets go through some of the claims.

18.11.2025 20:05 β€” πŸ‘ 75    πŸ” 17    πŸ’¬ 8    πŸ“Œ 4
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Our microbial-opsin work (and most of the field ) is basic science, but it was intriguing to review clinical progress–direct & indirect–with a wonderful team of co-authors
t.co/JrJen2WGBV
& adapt a fig. of PMID:28912215 (2017) with my long-time collaborator Peter Hegemann (pic: a memory from 2017).

18.11.2025 20:52 β€” πŸ‘ 28    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
Massachusetts Institute of Technology, Department of Brain & Cognitive Sciences Job #AJO30586, Assistant Professor level or higher, Department of Brain & Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, US

Two weeks left to apply! MIT's Department of Brain and Cognitive Sciences is seeking a tenure-track Assistant Professor, working with nonhuman animals in some way. Application deadline is Dec. 1. Full posting: academicjobsonline.org/ajo/jobs/30586

18.11.2025 15:09 β€” πŸ‘ 23    πŸ” 18    πŸ’¬ 2    πŸ“Œ 2
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Cocaine seeking and consumption are oppositely regulated by mesolimbic dopamine in male rats - Nature Communications Here authors demonstrate how opposing trajectories of dopamine transmission underlie changes in drug seeking and taking over chronic drug use. Increased dopamine to drug cues elevates craving, whereas...

Thought now was as good a time as ever to join bsky - Excited to share a big part of my PhD work is finally published- 7+ years of experiments from a great team of people. Wishing I could be at #sfn2025 to celebrate with you guys! www.nature.com/articles/s41...

13.11.2025 23:09 β€” πŸ‘ 35    πŸ” 10    πŸ’¬ 2    πŸ“Œ 1
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Cocaine seeking and consumption are oppositely regulated by mesolimbic dopamine in male rats - Nature Communications Here authors demonstrate how opposing trajectories of dopamine transmission underlie changes in drug seeking and taking over chronic drug use. Increased dopamine to drug cues elevates craving, whereas...

Awesome work by lead author Lauren Burgeno et al: Dopamine evoked by non-contingent cues increases over cocaine use, producing greater cue reactivity; whereas dopamine evoked by contingent cues decreases over cocaine use, producing escalation of drug consumption. www.nature.com/articles/s41...

12.11.2025 20:32 β€” πŸ‘ 31    πŸ” 9    πŸ’¬ 3    πŸ“Œ 0
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Our lab is looking for a postdoc! We have interesting projects and cutting-edge techniques such as Neuropixels Opto, Light Beads Microscopy and more. We would be delighted to receive your application. Deadline is 25 November 2025. More info here:
www.ucl.ac.uk/cortexlab/po...

12.11.2025 15:41 β€” πŸ‘ 39    πŸ” 26    πŸ’¬ 0    πŸ“Œ 0
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A genome-wide analysis of the shared genetic risk architecture of complex neurological and psychiatric disorders Nature Neuroscience - Smeland et al. demonstrate greater genetic overlap between neurological and psychiatric disorders than previously recognized, along with diverse neurobiological associations....

Excited to share our cross-disorder GWAS analysis of neurological and psychiatric disorders (~1 M cases), now out in @natneuro.nature.com! We show more extensive genetic pleiotropy than previously recognized, supporting a more unified view of these disorders
rdcu.be/ePmwD

12.11.2025 12:12 β€” πŸ‘ 17    πŸ” 13    πŸ’¬ 1    πŸ“Œ 0
(C) Recruitment of the WT PIKfyve-CCR-Kina to Rab5 endosomes and changes in biosensor localization at these membranes is
shown by the fluorescence intensity ratios of the constructs at Rab5 endosomes over the whole cell. Data shown is the grand
mean Β± SEM of 3 experiments. A total of 35 cells were analyzed. Confocal images over time are shown to the right. (D) As in C,
but now utilizing the catalytically dead K1876E/V1883I mutant of the FKBP-PIKfyve-CCR-Kina as a negative control.

(C) Recruitment of the WT PIKfyve-CCR-Kina to Rab5 endosomes and changes in biosensor localization at these membranes is shown by the fluorescence intensity ratios of the constructs at Rab5 endosomes over the whole cell. Data shown is the grand mean Β± SEM of 3 experiments. A total of 35 cells were analyzed. Confocal images over time are shown to the right. (D) As in C, but now utilizing the catalytically dead K1876E/V1883I mutant of the FKBP-PIKfyve-CCR-Kina as a negative control.

Independent validation of the SnxA biosensor as a sensitive reporter of PI(3,5)Pβ‚‚ dynamics by Gerald R Hammond and team: www.biorxiv.org/content/10.1...

12.11.2025 18:57 β€” πŸ‘ 14    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

The Matthew Effect is alive and well in academia - always makes me wary of programs aimed at identifying rising stars in an already highly talented pool...

elifesciences.org/reviewed-pre...

12.11.2025 19:03 β€” πŸ‘ 21    πŸ” 13    πŸ’¬ 4    πŸ“Œ 0
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Subsecond dopamine fluctuations do not specify the vigor of ongoing actions Nature Neuroscience - Liu and colleagues show that the vigor (that is, speed and amplitude) of dexterous movements is not controlled by ongoing fluctuations in extracellular dopamine within the...

Delighted to see this finally out: rdcu.be/eO9oW
We tested whether brief striatal dopamine release events influence the vigor of skilled movements. Despite popular belief, we did not find any evidence linking rapid dopamine dynamics to motor vigor on a moment-by-moment basis.

10.11.2025 15:43 β€” πŸ‘ 74    πŸ” 24    πŸ’¬ 9    πŸ“Œ 0
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Postdoc Position: Neural Circuitry Underlying Working Memory | Radboud University Do you want to work as a Postdoc Position: Neural Circuitry Underlying Working Memory at the Faculty of Social Sciences? Check our vacancy!

🚨🧠🚨 POSTDOC POSITION 🚨🧠🚨 in my lab: www.ru.nl/en/working-a... Connectivity in Working Memory. Deadline 12 Nov! Apply via website; please repost.

09.11.2025 09:17 β€” πŸ‘ 37    πŸ” 38    πŸ’¬ 1    πŸ“Œ 0
2026 Frontal Cortex Conference GRC The 2026 Gordon Research Conference on Frontal Cortex will be held in Holderness, New Hampshire. Apply today to reserve your spot.

What an exciting program for GRC Frontal Cortex in 2026! www.grc.org/frontal-cort...

03.11.2025 19:18 β€” πŸ‘ 30    πŸ” 12    πŸ’¬ 1    πŸ“Œ 1
Attention Authors: Updated Practice for Review Articles and Position Papers in arXiv CS Category – arXiv blog

arXiv will no longer accept review articles and position papers unless they have been accepted at a journal or a conference and complete successful peer review.

This is due to being overwhelmed by a hundreds of AI generated papers a month.

Yet another open submission process killed by LLMs.

01.11.2025 17:28 β€” πŸ‘ 1575    πŸ” 611    πŸ’¬ 19    πŸ“Œ 73
Associate/Full Professor - Affective Motivational Neuroscience Position DescriptionThe Department of Neuroscience in the School of Behavioral and Brain Sciences at The University of Texas at Dallas seeks a late-stage Associate or Full Professor faculty member to ...

We are seeking a senior tenured professor in our Department working on affective and/or motivational neuroscience (defined in the ad, but pretty broad). The idea is that this person is going help lead our growth in this area alongside our excellent Centers. jobs.utdallas.edu/postings/30693

31.10.2025 21:15 β€” πŸ‘ 14    πŸ” 17    πŸ’¬ 1    πŸ“Œ 3

Ventral tegmental area dopamine controls timing variability https://www.biorxiv.org/content/10.1101/2025.10.27.684913v1

28.10.2025 20:15 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Join us from September 7-10 (2026) in Amsterdam for the "Monitoring Molecules in Neuroscience" conference! The conference venue is booked, the plenary speakers are invited, and we are starting to work on the scientific program. More news to follow soon! monitoringmolecules.org/mmin-2026/

28.10.2025 10:24 β€” πŸ‘ 8    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Looking to improve your PeerReview skills? The Reviewer Mentor Program pairs trainees with #JNeurosci & #eNeuro editors & top reviewers to conduct strong manuscript reviews. Open to SfN members at any career stage: http://www.jneurosci.org/rmp

25.10.2025 10:31 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Abstract submissions are now OPEN for the Dopamine 2026 meeting!

Share your latest discoveries and join the global dopamine community in advancing the science of motivation, movement, and reward.

Submit here: dopaminesociety.org/abstracts/

#Dopamine2026

22.10.2025 06:41 β€” πŸ‘ 5    πŸ” 7    πŸ’¬ 0    πŸ“Œ 1
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🚨 Countdown begins!

Only one month until the call for abstracts, travel grants and registrations open for #FENS2026! 🧠

πŸ—“οΈ Mark your calendars!
πŸ‘‰ https://loom.ly/0eQS4lE

#FENS #BrainResearch #NeuroscienceConference #FENSForum

17.10.2025 11:00 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Out today at Neuron, our experiments show that frontal cortical representation of economic variables is jointly determined by spatial organization and downstream
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...

16.10.2025 14:59 β€” πŸ‘ 95    πŸ” 26    πŸ’¬ 6    πŸ“Œ 0

@willuhnlab is following 20 prominent accounts