Fabian Spill

Frontiers | A hybrid computational model of cancer spheroid growth with ribose-induced collagen stiffening

Congrats Margherita for her new paper, where she investigated how cancer spheroids grow in collagen matrices with varying stiffness, implementing varying ECM properties in @physicell.bsky.social Thanks Tom Susan John and Pradeep for the collaboration
www.frontiersin.org/journals/bio...

We may not have really squared the circle — but we came close! 😉 In our @NaturePhysics paper w/ @fakhrilab.bsky.social, light-triggered membrane excitability enables programmable shapes — a step toward engineering living matter.
🔗 www.nature.com/articles/s41...
#biophysics #syntheticcell #softmatter

Continuum Mechanics in Biology 2025 A three-day workshop addressing the growing interface between continuum mechanics and the life sciences

Meeting at the mathematical modelling/biology interface, in Birmingham in July, organised by @rosemaryjdyson.bsky.social & colleagues.

sites.google.com/view/continu...

🧪🌱🌿

@xiaofu90.bsky.social

@blindmath.bsky.social

@krasimiratsaneva.bsky.social

@kityates.bsky.social

@micromotility.bsky.social

@profruthbaker.bsky.social

@gibin.bsky.social

Excited to announce that registration for UK Maths Bio 2025 is open. We have an exciting list of confirmed speakers and are looking for more exciting talks and posters from the community. Please submit your abstract by 31 March 25.

ukmathbioconference.github.io

Leveraging computational modeling to explore epithelial and endothelial cell monolayer mechanobiology Endothelial cells (ENCs) and epithelial cells (EPCs) form monolayers whose barrier function is critical for the maintenance of physiological processes and extremely sensitive to mechanical cues. Compu...

Our new review discusses how mathematical models can help understand the similarities and differences between endothelial and epithelial cells. Thanks
Pradeep, Raul, Maria Jose and
Effie for the collaboration www.cell.com/trends/cell-...

The role of mutants in the spatio-temporal progression of inflammatory bowel disease: three classes of permanent form travelling waves Despite its high prevalence and impact on the lives of those affected, a complete understanding of the cause of inflammatory bowel disease (IBD) is lacking. In this paper, we investigate a novel mecha...

arxiv.org/abs/2501.07205

And congrats @Blaine_VR again, I can't recall I ever had two papers on ArXiv on the same day :) This model is about IBD and identified how mutants and inflammation affect the spread

Eco-evolutionary dynamics of a trait-structured predator-prey model The coupling between evolutionary and ecological changes (eco-evolutionary dynamics) has been shown to be relevant among diverse species, and is also of interest outside of ecology, i.e. in cancer evo...

Congrats Blaine for completing the paper 'Eco-evolutionary dynamics of a trait-structured predator-prey model' which features an analytic analysis of a model with population heterogeneity, transient, and long-term dynamics arxiv.org/abs/2501.07379

@blindmath.bsky.social @krasimiratsaneva.bsky.social @kityates.bsky.social @micromotility.bsky.social @profruthbaker.bsky.social @gibin.bsky.social

Excited to announce the first UK Maths Bio Conference 4-5 September in Birmingham ukmathbioconference.github.io . Registration will open in a few weeks, save the date! Thanks to my amazing co-organisers Valeria, Kyle, Rachel and Phil for all their work planning the conference.

iTARGET: Interpretable Tailored Age Regression for Grouped Epigenetic Traits Accurately predicting chronological age from DNA methylation patterns is crucial for advancing biological age estimation. However, this task is made challenging by Epigenetic Correlation Drift (ECD) a...

Congrats Zipeng on completing his paper iTARGET:Interpretable Tailored Age Regression for Grouped Epigenetic Traits arxiv.org/abs/2501.02401

could be used to identify researchers working on any disease in any region or country Congrats again Rico, great work that started with his master thesis work, thanks to our colleagues Natanya and Sue at BMS and also Sam and Jean-Baptiste for the collaboration 3/3

multiple myeloma in sub-Saharan Africa, and wanted a tool that can be used to identify leading research institutes or hospitals with expertise in myeloma in specific locations. But the network tool Rico developed 2/

Congrats Rico on publishing his article 'Network analysis of cross-income-level collaboration on multiple myeloma in sub-Saharan Africa'. This paper was motivated to increase global representation in biomedical research. Our collaborators at BMS were specifically interested in t.co/Tj6ShrUoVA 1/

Systems-Mechanobiology - Jobs

Still time to apply for positions in Maths @unibirmingham. We hire on every level, from PhD students to prestigious 125 Anniversary Chair positions, deadline early January. Please spread the word! www.systems-mechanobiology.com/jobs

and inferring how these affect cell functions, such as metabolism or cell migration, in ageing and diseases. But we are open to hearing about your ideas within the broad space of systems models in ageing and diseases edzz.fa.em3.oraclecloud.com/hcmUI/Candid... 2/2

I am looking for a postdoc to join our interdisciplinary team developing mechanistic or machine learning systems models of ageing and age-related diseases. One focus is on identifying geometrical and mechanical alterations such as cell and organelle shape changes 1/

Modelling Metabolic Drivers of Ageing and Diseases at University of Birmingham on FindAPhD.com PhD Project - Modelling Metabolic Drivers of Ageing and Diseases at University of Birmingham, listed on FindAPhD.com

I am looking for PhD students who love to develop models and ML methods to understand how mechanical, geometrical or metabolic features of cells and tissue change in aging, and how this affects the emergence of age-related diseases. www.findaphd.com/phds/project... www.findaphd.com/phds/project...

We are looking for a PhD student who is excited about mitochondria and their role in diabetes t.co/Y0fPG459Ad

Assistant Professor (Research and Education) at University of Birmingham Explore an exciting academic career as a Assistant Professor (Research and Education). Don't miss out on other academic jobs. Click to apply and explore more opportunities.

We have multiple positions as Assistant and Associate Professor at the University of Birmingham in any area of Mathematics available. Come join our collaborative environment and please spread the word. www.jobs.ac.uk/job/DKT142/a...