Very cool technique!๐
12.06.2025 23:04 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0
Inceptor binds to and directs insulin towards lysosomal degradation in ฮฒโcells - Nature Metabolism
The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.
Thrilled to share one of our biggest discoveries: โInceptor binds to and directs insulin towards lysosomal degradation in beta cellsโ.
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
25.11.2024 11:16 โ ๐ 130 ๐ 53 ๐ฌ 6 ๐ 5
Head of Section of Cell Biology and Functional Genomics, MDR Department, Imperial College London. Subcellular signalling organisation of the glucagon receptor family.
https://www.imperial.ac.uk/people/a.tomas-catala
The Jackson Laboratory, Bar Harbor, ME
Islet biology, Incretins, mouse models, obesity, diabetes, TPx
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Researching the interplay between factors underlying metabolic health and disease, including diet, age, environment, and genetics, for the prevention and treatment of widespread chronic diseases. https://hsph.harvard.edu/department/molecular-metabolism/
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We publish Reviews and opinion articles on all aspects of endocrinology and metabolism.
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Your leading source of international, cutting-edge research, review, and opinion in clinical #diabetes and #endocrinology. IF=41ยท8.
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Diabetes Reseach Envisioned and Accomplished in Manitoba (DREAM)
A translational research team aimed at improving the world of families & children living with diabetes.
www.dreamdiabetesresearch.com
contact: dream@chrim.ca
Research Fellow in Translational & Regenerative Medicine.
Interested in understanding and developing cell therapies for Type 1 Diabetes and Liver Disease.
Zymurgist and Wrangler of Bumblenuts
Takes the scenic route ๐ณ ๐๐ด | Edinburgh, UK | He/Him ๐
Diabetes, Obesity, and Metabolic Researcher. Chief of Endocrinology and Metabolism at UCSF Health. Here for the patients. My opinions are mine.
Sugar stimulated and oozing goodness
๐ฅEndocrinologist (Hormone Physician)
๐ฅBoard certified endocrinology/diabetes/metabolism & obesity medicine
๐ฅCohost DocsWhoLift podcast
๐ฅEndocrine Clinic at the Gym