Parkinsonian striatal acetylcholine dynamics are refractory to L-DOPA treatment https://www.biorxiv.org/content/10.1101/2025.11.06.686401v1
07.11.2025 22:15 β π 2 π 1 π¬ 0 π 0@jonesparker.bsky.social
Assistant Professor of Neuroscience at Northwestern University. Studying the dopamine system in normal and pathological behaviors. http://www.parkerlaboratory.com
Parkinsonian striatal acetylcholine dynamics are refractory to L-DOPA treatment https://www.biorxiv.org/content/10.1101/2025.11.06.686401v1
07.11.2025 22:15 β π 2 π 1 π¬ 0 π 0why bother when our <5th percentiles are turned away?
18.09.2025 20:05 β π 2 π 0 π¬ 1 π 0Great to hear. Congrats!
10.03.2025 23:04 β π 2 π 0 π¬ 1 π 0Any update on the outcome of this. Did you ever receive NoA?
10.03.2025 15:38 β π 0 π 0 π¬ 1 π 0One of my colleagues was asked to do an βinterim no cost extensionβ in lieu of an NOA. Didnβt even know that was a thing.
01.03.2025 23:19 β π 6 π 0 π¬ 1 π 1Though not posted to the register, SMN study section is tentatively re-scheduled for 4/22-4/23.
For anyone lurking here for this information (as I do for an MCNP re-scheduling announcement).
Ooof. What a depressing outlook. So bad for people at NIH, us, and the country as a whole.
27.02.2025 19:47 β π 1 π 3 π¬ 0 π 0Freezing out the NIH's funding means freezing out American innovation.
Research into curing cancer, Alzheimer's, and Parkinson's all delayed.
And ultimately it won't just cost us advancements in life-saving research, it will cost us lives.
A large portion of grants awarded by the U.S. National Institutes of Health cannot be funded for the foreseeable future because of an indefinite hold on submissions to the Federal Register, according to an email reviewed by The Transmitter.
By @avaskham.bsky.social
bit.ly/3X8ngz8
saw that. bummer. I have one at study section this week (not on register) and am scheduled to be on a study section next week (also not on register).
17.02.2025 17:19 β π 0 π 0 π¬ 0 π 0This seems to be the next one that isnβt listed in the register. Scheduled to meet tomorrow. public.era.nih.gov/pubroster/pr...
17.02.2025 15:18 β π 1 π 0 π¬ 1 π 0Maybe all the checking to see if it's offline overloaded the server π
03.02.2025 22:22 β π 1 π 0 π¬ 0 π 0Like ribbon candy
10.01.2025 17:16 β π 1 π 0 π¬ 0 π 0I saw these camping in TN after thanksgiving. No idea how this occurs.
10.01.2025 15:51 β π 3 π 1 π¬ 1 π 0As someone who worked with dopamine deficient mice and DAT-TH KO mice that were largely βnormalβ (not cited therein), Iβd say thatβs a big MAYBE. Something going on there, we donβt know what, and is doesnβt prove that the dynamics are unimportant under physiologically relevant conditions.
22.11.2024 00:51 β π 2 π 0 π¬ 0 π 0Reposting for the grad school applicants who may have recently joined the blue place. Also will be at ABRCMS so swing on by booth 639!
12.11.2024 19:24 β π 6 π 6 π¬ 0 π 0A starter pack! Some of my favorite women in neuroscience (sorry if I forgot you, I will add!)
go.bsky.app/SCFmKoC
I made a starter pack for neuroscience folks but I just saw that itβs capped at 150 people. Sorry if I missed anyone! Maybe #neuroscience folks should start making subfield starter packs? π§ͺ
go.bsky.app/Q69XurQ
My plea to Dem leaders, liberal elites, social scientists, and every critical thinker who wants to keep fighting is to think beyond the perennial assumption that working-class drift can only be arrested by tweaking economic policy or talking points. Free to all. www.offmessage.net/p/democrats-...
08.11.2024 18:27 β π 210 π 59 π¬ 15 π 18Yes. Great to see! I shut mine down for good Wednesday.
09.11.2024 14:13 β π 2 π 0 π¬ 0 π 0My run after lab meeting this morning!
07.11.2024 18:57 β π 2 π 0 π¬ 0 π 0Cool new pre-print from the Ford lab.
www.biorxiv.org/content/10.1...
I'm in! Follow for content related to dopamine, in vivo imaging, and neuropharmacology. #neuroscience
10.09.2023 14:58 β π 16 π 4 π¬ 1 π 0