Javier Irazoqui

Here's the Baldwin amendment that DOES effectively prevent NIH from implementing multi-year funding.

Deleted my previous post; the amendments hadn't been posted yet. h/t @davidimiller.bsky.social

I’ll believe it when it’s in the books

The NIH budget will INCREASE by $400 million — not slashed by 40%, as Trump proposed — according to a proposal by Senate appropriators, says Sen Murray.

"Some have asked if there will even be an NIH by [2029]. The commmittee's resounding message is yes—Congress has your back", she says.

a man in a silver suit is standing in front of a building and talking about chocolate orange . ALT: a man in a silver suit is standing in front of a building and talking about chocolate orange .

‘What is this? A spine for ANTS?’

a group of young men are dancing in a park . one of the men is wearing a hoodie . ALT: a group of young men are dancing in a park . one of the men is wearing a hoodie .

Hahahahaha savage

2/…. But in the English-speaking world, it has no precedent, he told me: “This is an unparalleled destruction from within.”

My prediction: per-publication cost ceilings will finally incentivize journals to make individual publications shorter!

Why would a journal accept $3,000 for a publication with a 90-page supplement when they could split it into four different publications published back-to-back and get $12k?

I just circulated this to faculty in my Department and encourage you all to do likewise

"Dear Colleagues
NIH has issued a Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs, and is looking for feedback. Please consider responding.

GeneAgent: self-verification language agent for gene-set analysis using domain databases - Nature Methods GeneAgent is a language agent using large language models and self-verification to improve gene-set function annotation.

GeneAgent: self-verification language agent for gene-set analysis using domain databases
Paper: www.nature.com/articles/s41...
Code: github.com/ncbi-nlp/Gen...
Demo: www.ncbi.nlm.nih.gov/CBBresearch/...

Usually, I would think executive branch officials would comply with such requests to avoid angering the people with the checkbook.

Here, they might not care. If they don't comply with "directives", what are appropriators going to do, cut their appropriations? They want them to do that anyway!

I think they saw a losing battle with Congress

Every Scientific Empire Comes to an End — The Atlantic America’s run as the premiere techno-superpower may be over.

Every Scientific Empire Comes to an End - The Atlantic

apple.news/AflXtTv8rTVe...

Hi! What do you mean by signals?

Practical and Positive Uses of AI in STEM Education - From the J. in Μicro & Bio Ed
journals.asm.org/journal/jmbe...

My second NCR was awarded, one day early.

NIH staff must be working around the clock to push funding out.

Let's thank our POs and SROs and all NIH staff for working selflessly to keep science progressing in this sh*tshow.

Whoa!

Meanwhile.

CRISPR-GPT for agentic automation of gene-editing experiments - Nature Biomedical Engineering An agent-based large language model (LLM) tool helps with CRISPR-based gene-editing experimental design and analysis.

"We present CRISPR-GPT, an LLM agent system to automate and enhance CRISPR-based gene-editing design and data analysis."

www.nature.com/articles/s41...

DOJ Declares Slew of DEI Practices Unlawful in Memo The nine-page memo builds on the Trump administration’s efforts to dismantle diversity, equity and inclusion programs.

www.insidehighered.com/news/governm...

All Federal agencies are required by 31 U.S.C. §1552(a) to close fixed year appropriation accounts and cancel any remaining balances by September 30 of the fifth fiscal year after the year of availability unless otherwise authorized by Congress. In order for NIH to meet its obligation to close these accounts and cancel any remaining balances by September 30, recipients must report disbursements on the FFR no later than August 31 of the fifth fiscal year after the year of availability. This provision may limit the availability of funds for carryover. It may also limit or eliminate the authority to extend the final budget period when an entire project period is funded by a single award (e.g., multiyear funded awards).

I don't know, but I just realized that 5-year awards might not be able to get a no-cost extension and 4-year awards might not be able to get one for a full year. Caveat recipiens. grants.nih.gov/grants/polic...

This certainly appears to be the reason for 4 year award of the MYF’d grants.

Trump administration reverses course, lifts pause on NIH grant awards The order applies to the entirety of new and, possibly, ongoing research grant dollars that go to universities and academic medical centers.

Another take

www.statnews.com/2025/07/29/t...

Trump administration halts, then releases, NIH research funding The decision temporarily froze $15 billion in federal funding, according to one senator. It came as Trump officials wrestle over federal spending levels.

A senior leader at one NIH institute said: “At my level we are legitimately trying to figure out how to keep funding high-impact science given what we expect will happen.”
The senior leader added: “Our grants people are barely holding it together because they are at the center of this chaos.”

Trump Administration Scraps Effort to Pause Health-Research Funding The administration halted and then restarted billions in new research grants flowing from the National Institutes of Health.

UPDATE: The pause was scrapped Tuesday evening after intervention by top White House officials. www.wsj.com/politics/pol...

“Revolutionary Science Comes from Unexpected Angles”

Thoughts from our own Tom Rapoport on the role of basic science in curing disease. magazine.hms.harvard.edu/articles/rev...

Research Fellow - Department of Immunology and Immunotherapy - 106119 - Grade 7 The successful candidate will make extensive use of a range of in vivo models of fungal infection and will have access to the wide range of transgenic tools and in vivo immunology techniques establish...

Job ads for TWO postdoctoral positions available in our group are now online. Deadline August 25th.
🧪Immunologists, apply in link below.
🍄Microbiologists- please follow link in next post.
edzz.fa.em3.oraclecloud.com/hcmUI/Candid...

I feel dizzy

Is this all frozen funds?

Given that OMB is part of the Executive Office of the President, this should read

"after intervention by OTHER top White House Officials."