Ivan Alcantara's Avatar

Ivan Alcantara

@ivancalcantara.bsky.social

Asking how the environment impacts behavior, physiology & brain function 🌎🧠 β€’ CV Starr Postdoctoral Fellow at Princeton Neuroscience Institute β€’ PhD in Neuroscience at NIH & Brown University β€’ MSc in Cell Biology at MPI for Brain Research he/him πŸ³οΈβ€πŸŒˆπŸ‡΅πŸ‡­

3,639 Followers  |  601 Following  |  56 Posts  |  Joined: 29.09.2023  |  2.5376

Latest posts by ivancalcantara.bsky.social on Bluesky

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No labor today

01.09.2025 23:46 β€” πŸ‘ 10    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

It should be said too that in the two-state solution scenario, this would still happen because apartheid with all its anti-miscegenation tendencies would still be baked in

29.08.2025 12:27 β€” πŸ‘ 148    πŸ” 44    πŸ’¬ 3    πŸ“Œ 0
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Research posts on Bluesky are more original β€” and get better engagement Bluesky posts about science garner more likes and reposts than similar ones on X.

@nature.com I love this article - but WHY are the only share options to X and Facebook when the whole point of the article is that science-based posts get more shares here?

www.nature.com/articles/d41...

29.08.2025 16:49 β€” πŸ‘ 1681    πŸ” 340    πŸ’¬ 37    πŸ“Œ 17

Underrepresented minority faculty in the USA face a double standard in promotion and tenure decisions

16.08.2025 00:54 β€” πŸ‘ 81    πŸ” 35    πŸ’¬ 3    πŸ“Œ 2

Me not knowing I missed a paper from the 80’s

08.08.2025 17:18 β€” πŸ‘ 9    πŸ” 0    πŸ’¬ 1    πŸ“Œ 1
development organizations years following the Effectiv
brown.edu Private
rimination laws, over the ten
10. t h he exception of actions to enforce this Agreement, the United States agrees not to institute any civil action or other adverse agency action against Brown, its officers, Corporation members, directors, agents, and employees (the "Brown Releasees) based on the Released Claims. The United States releases the Brown Releasees from any liability related to the Released Claims. The United States is not releasing Brown or the Brown Releases from any other liability.
11. The University will take the following steps to ensure compliance with Title IX and its implementing regulations, by providing safe and equitable opportunities and spaces for women:
a. Brown Athletics facilities, the University willprovide female student-athletes with intimate facilities such as locker rooms and bathrooms strictly separated on the basis of sex.
b. The University will define "male" and "female, for the purpose of all practices, policies and procedures adopted and implemented by the University for any athletic opportunity, event, competition, category, program, or activity designated for women, consistent with the definitions
3
adopted in Executive Order 14168, Defending Women from Gender Ideology Extremism and estoring Biological Truth to the Federal Government (Jan. 20, 2025), and Executive Order 14201, Keeping Men out of Women's Sports (Feb. 5, 2025).
c. The University will offer women the option of female-only housing, restrooms, and showering facilities, and for these purposes will adopt the abovementioned definitions of "male' and "femalc."
d. The University will ensure students have access to single-sex floors in on-campus housing, using the above-mentioned definition.
12. h University will not perform gender reassignment surgery or prescribe puberty blockers or hormones to any minor child for the purpose of aligning the child's appearance with an identity that differs from hi…

development organizations years following the Effectiv brown.edu Private rimination laws, over the ten 10. t h he exception of actions to enforce this Agreement, the United States agrees not to institute any civil action or other adverse agency action against Brown, its officers, Corporation members, directors, agents, and employees (the "Brown Releasees) based on the Released Claims. The United States releases the Brown Releasees from any liability related to the Released Claims. The United States is not releasing Brown or the Brown Releases from any other liability. 11. The University will take the following steps to ensure compliance with Title IX and its implementing regulations, by providing safe and equitable opportunities and spaces for women: a. Brown Athletics facilities, the University willprovide female student-athletes with intimate facilities such as locker rooms and bathrooms strictly separated on the basis of sex. b. The University will define "male" and "female, for the purpose of all practices, policies and procedures adopted and implemented by the University for any athletic opportunity, event, competition, category, program, or activity designated for women, consistent with the definitions 3 adopted in Executive Order 14168, Defending Women from Gender Ideology Extremism and estoring Biological Truth to the Federal Government (Jan. 20, 2025), and Executive Order 14201, Keeping Men out of Women's Sports (Feb. 5, 2025). c. The University will offer women the option of female-only housing, restrooms, and showering facilities, and for these purposes will adopt the abovementioned definitions of "male' and "femalc." d. The University will ensure students have access to single-sex floors in on-campus housing, using the above-mentioned definition. 12. h University will not perform gender reassignment surgery or prescribe puberty blockers or hormones to any minor child for the purpose of aligning the child's appearance with an identity that differs from hi…

president.brown.edu Private

BROWN

5. Addressing government requirements for "male" and
"female" defnitions for athletics and on-campus housing,
as well as limits on gender-affirming care

As we have for decades, Brown has agreed to abide by Title
IX and NCAA eligibility rules regarding the participation of
transgender athletes in intercollegiate sports. We also
committed that the University will continue to provide
housing and restroom access in a way that allows for gender-
inclusive, women-only and men-only options.

The agreement also states, The University will not perform
gender reassignment surgery or prescribe puberty blockers
or hormones to any minor child for the purpose of aligning
the child's appearance with an identity that differs from his or
her sex."' The University will refer affected students who seek
care from Student Health Services or the University
Pharmacy to area specialists. The agreement does not affect
medical teaching or training, and does not apply to clinical
services provided by health systems that are separate entities
from Brown, such as Brown University Health and Care New
England.

We remain fully commited to serving the health needs of all
Brown students in a manner consistent with our long-
established policy of nondiscrimination, which includes sex,
gender identity and gender expression. The LGBTQ Center,
Student Health and Wellness Services, and other offices in
the Division of Campus Life, as well as the Warren Alpert
Medical School School of Public Health. the College,

president.brown.edu Private BROWN 5. Addressing government requirements for "male" and "female" defnitions for athletics and on-campus housing, as well as limits on gender-affirming care As we have for decades, Brown has agreed to abide by Title IX and NCAA eligibility rules regarding the participation of transgender athletes in intercollegiate sports. We also committed that the University will continue to provide housing and restroom access in a way that allows for gender- inclusive, women-only and men-only options. The agreement also states, The University will not perform gender reassignment surgery or prescribe puberty blockers or hormones to any minor child for the purpose of aligning the child's appearance with an identity that differs from his or her sex."' The University will refer affected students who seek care from Student Health Services or the University Pharmacy to area specialists. The agreement does not affect medical teaching or training, and does not apply to clinical services provided by health systems that are separate entities from Brown, such as Brown University Health and Care New England. We remain fully commited to serving the health needs of all Brown students in a manner consistent with our long- established policy of nondiscrimination, which includes sex, gender identity and gender expression. The LGBTQ Center, Student Health and Wellness Services, and other offices in the Division of Campus Life, as well as the Warren Alpert Medical School School of Public Health. the College,

Brown University is caving to Trump.

They are banning trans women from female bathrooms, dorms, locker rooms, and sports across campus. They're also cracking down on trans care for minors, though that is unlikely to be broadly impactful since it's a university.

president.brown.edu/president/br...

30.07.2025 22:30 β€” πŸ‘ 1028    πŸ” 379    πŸ’¬ 50    πŸ“Œ 123

I am honored to be selected as an ASCB fellow! SO much thanks to those who nominated me and provided letters of support!

And congratulations to the other Fellows selected! πŸŽ‰πŸ₯³πŸŽŠ

07.08.2025 16:24 β€” πŸ‘ 202    πŸ” 24    πŸ’¬ 52    πŸ“Œ 0
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Epigenetic regulation of brain development, plasticity, and response to early-life stress Neuropsychopharmacology - Epigenetic regulation of brain development, plasticity, and response to early-life stress

Review now out in @npp-journal.bsky.social!
Epigenetic regulation of brain development, plasticity, and response to early life stress
rdcu.be/ezzYq

06.08.2025 15:38 β€” πŸ‘ 75    πŸ” 27    πŸ’¬ 1    πŸ“Œ 1
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A hypothalamic circuit that modulates feeding and parenting behaviours - Nature Single-cell transcriptomic analysis of mouse hypothalamus and behavioural experiments show that specific hypothalamic networks regulate conflicting feeding versus parenting behaviours of female mice.

Nature research paper: A hypothalamic circuit that modulates feeding and parenting behaviours

go.nature.com/4l0XKoB

05.08.2025 08:58 β€” πŸ‘ 26    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
GEO Accession viewer NCBI's Gene Expression Omnibus (GEO) is a public archive and resource for gene expression data.

While our analyses only focused on neurons, we also collected and sequenced non-neuronal cell types. If you’re interested in these cell types or if you’d like to analyze the neurons from scratch, feel free to dive into the raw data: www.ncbi.nlm.nih.gov/geo/query/ac...

04.08.2025 16:07 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Ever wondered how fasting and lactation affect gene expression in the hypothalamus? Looking for a dataset to mine? Look no further! We performed single-cell RNA sequencing of the arcuate nucleus and medial preoptic area in 4 groups of female mice: zenodo.org/records/1531...

04.08.2025 16:07 β€” πŸ‘ 12    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0

Thanks Giacomo!!!

31.07.2025 21:09 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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A hypothalamic circuit that modulates feeding and parenting behaviours - Nature Single-cell transcriptomic analysis of mouse hypothalamus and behavioural experiments show that specific hypothalamic networks regulate conflicting feeding versus parenting behaviours of female mice.

www.nature.com/articles/s41...

31.07.2025 15:29 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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This is probably my favorite comment from a reviewer. Sometimes, less is more πŸ˜‰

Read the full transcript of the reviewers’ comments and our responses for our recent @nature.com publication here: static-content.springer.com/esm/art%3A10...

31.07.2025 15:28 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Thanks Cate! You guys are next! πŸ˜„

31.07.2025 01:04 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you! Miss you and the rest of the Correa lab!

30.07.2025 23:15 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Really cool work! I actually presented the preprint at journal club the day before it came out in Nature πŸ˜…

30.07.2025 23:04 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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🚨Very happy that my PhD work is now out in @nature.com!

We discovered that evolution, by acting in the midbrain, shifted the threshold to escape in Peromyscus mice, to fine-tune defensive strategies in different environments

www.nature.com/articles/s41...

This was a truly collaborative effort! πŸ§΅β¬‡οΈ

23.07.2025 15:05 β€” πŸ‘ 467    πŸ” 101    πŸ’¬ 26    πŸ“Œ 5

Thanks Andrew!

30.07.2025 22:53 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you! πŸ€—

30.07.2025 22:33 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Alcantara_Krashes_Nature_2025.pdf

PDF here if the article is paywalled: drive.google.com/file/d/1bGCy...

30.07.2025 19:03 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Thanks RamΓ³n for not only running experiments but also providing your expert advice on BRS3 neurons. Not a tiny contribution!

30.07.2025 18:33 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you! 😊

30.07.2025 17:54 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you Tom!

30.07.2025 17:54 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks Zeena!

30.07.2025 17:54 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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A hypothalamic circuit that modulates feeding and parenting behaviours - Nature Single-cell transcriptomic analysis of mouse hypothalamus and behavioural experiments show that specific hypothalamic networks regulate conflicting feeding versus parenting behaviours of female mice.

Terrific study, led by @ivancalcantara.bsky.social, on the neural circuitry underlying the prioritisation of competing motivated behaviors, out in @nature.com
πŸ§ͺ🧠
www.nature.com/articles/s41...

30.07.2025 17:06 β€” πŸ‘ 11    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0

Thanks so much! πŸ€—

30.07.2025 16:55 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Great question! Unfortunately we did not look at pup sex. Our assays consisted of 5 pups with likely mixed sexes, and moms are very good at retrieving all of them even if they’re hungry, although we don’t know if male or female pups are more likely to get retrieved first.

30.07.2025 16:54 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Last, stimulating AgRP neurons dampens the basal activity of BRS3 neurons, making them less responsive to pups. This AgRP-to-BRS3 circuit may therefore underlie the process through which hunger can redirect an animal’s motivations from caring for offspring to foraging for food.

30.07.2025 16:35 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
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Using single-cell RNA sequencing and neuronal manipulations, we identified an MPOA population important for parenting and satiety: bombesin receptor subtype-3 (BRS3) neurons. Activation of these neurons can even make some virgin males (which typically attack pups) more parental.

30.07.2025 16:35 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

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