Jane Coffin Childs Fund for Medical Research

for sleep disorders. See Elias' profile for more information about her exciting research!

www.jccfund.org/fellows/#mod...

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Leah Elias, Ph.D., is our Featured Fellow! Elias' postdoctoral research in @sethblackshaw.bsky.social's lab is dissecting how the need for restorative sleep is encoded into our brains at the level of cellular circuits and molecular signals. Her findings may reveal novel therapeutic targets ...
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Ok, you get the idea. Start getting your application ready, or help us spread the news!

If you have any questions about eligibility, please reach out to our program office!

www.jccfund.org/contact-us/

- Participate in the awesome annual symposium with JCC Fellows and Scientific Advisors. Recent years were held in NYC and Chicago, and next year is in Seattle. Where will we go next??? Apply and find out!

- Network with JCC alumni who are scientific leaders in academia, industry, and more!

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- For U.S. based labs, postdoc may be citizen of any country.
(Postdocs who are U.S. citizens are also eligible to apply through international labs.)

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Why should you apply for a JCC fellowship??? We're so glad you asked!

- Competitive stipends with extra allowances for research costs, travel to scientific meetings, and for dependents (if applicable)

- Stable funding.

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If you've recently started a postdoc, or are soon to start one in the field of biomedical research (broadly defined), you should apply!

If you know someone who fits this definition - tell them to apply!

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To Apply - Jane Coffin Childs Memorial Fund THE APPLICATION PORTAL IS NOW OPEN. The application will be due February 2, 2026 at 3pm EST. Access the application here. Eligibility Criteria to Apply in 2026 The applicant must meet all eligibility ...

The application portal for the 2026 cycle of Jane Coffin Childs Postdoctoral Fellowships is now live!

We'll be accepting applications through February 2nd, 2026 at 3PM EST.

www.jccfund.org/eligibilty-c...

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Also thankful for fellowship support from @hhmi.org in my PhD and now from @jcchildsfund.bsky.social!

#Neurodevelopment #Psychedelics #ChoroidPlexus #CSF #DevNeuro #Pregnancy #LSD #Preprint

Gestational psychedelic exposure disrupts brain development and offspring behavior in mice Despite increasing non-medical use and clinical investigation of psychedelics, the consequences of prenatal exposure remain unknown. In mice, maternal lysergic acid diethylamide (LSD; 0.3 mg/kg) cross...

TL;DR: Maternal psychedelics reach embryonic CSF within minutes, activate the choroid plexus, alter CSF, and shift cortical development in mice—yielding lasting behavioral changes. A discrete embryonic window is vulnerable via the ChP–CSF axis.

www.biorxiv.org/content/10.1...

Gestational psychedelic exposure disrupts brain development and offspring behavior in mice Despite increasing non-medical use and clinical investigation of psychedelics, the consequences of prenatal exposure remain unknown. In mice, maternal lysergic acid diethylamide (LSD; 0.3 mg/kg) cross...

🚨 Psychedelics in pregnancy - can a single dose reach the embryo and matter? Yes. In mice they hit embryonic CSF within minutes, activate choroid plexus→CSF axis, & shift cortical development with adult behavioral signatures. @lehtinenlab.bsky.social Preprint:

www.biorxiv.org/content/10.1...

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Our growing team at @uchicagocancer.bsky.social is building on these concepts, with the goal of translating this knowledge to improved therapies for metastatic cancers. More to come! (4/4)

Huge thanks to everyone who contributed to this team effort #LoweLabMSKCC #LabMassague @danapeer.bsky.social #ChristineIacobuzio #CPCRMSK @ronanchaligne.bsky.social #SAIL #RichardKoche #ERIL, and key funding support from #NCI @jcchildsfund.bsky.social #KatzmanFellowship #GMTEC! (3/4)

SMAD4 induces opposite effects on metastatic growth from pancreatic tumors depending on the organ of residence - Nature Cancer Using mouse pancreatic cancer models, Tsanov et al. show that reactivation of SMAD4 at metastatic sites promotes tumor growth in the lung through RUNX1 but restrains metastatic growth through KLF4 in the liver, influenced by organ-specific epigenetic states.

🚨Location, location, location! Now out @natcancer.nature.com, the final version of our study showing how a tumor's anatomic site can impact the function of driver gene mutations, using SMAD4 inactivation as in pancreatic cancer as a clinically relevant example: nature.com/articles/s43.... (1/4)

Science of the day: Some spikes are just more positive than others, at least waveform-wise.
Side science: interested in these positive units (Punits), check out this work by Shirly Someck www.nature.com/articles/s42...
#Neuroscience #neuroskyence #punits #PositiveVibes

Science of the day: the activity of thalamic neuronal population during slow wave sleep. Here, dozens of neurons synchronize their firing activity in a Delta rhythm
Side science: Shana Tova to you all! I hope this year will be a year of science and peace
#Neuroscience #neuroskyence #ShanaTova

Science of the day: the distance between shanks of this silicone probe, used for electrophysiological recordings from the brain, is 0.125 mm. For scale, a hair at the bottom of the image
Side science: my go to probe is the diagnostic biochips 8 shanks, 128 channels.
#Neuroscience #neuroskyence

Hu's research @hutchbasicsci.bsky.social may provide insight into how chromosome segregation goes awry leading to aneuploidy and cancer development.

Learn more about Dr. Hu and his fascinating research here:
www.jccfund.org/fellows/curr...
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Changkun Hu, PhD, is our featured fellow! Dr. Hu uses in vitro reconstitution and TIRF microscopy (😍😍) to investigate the kinetochore, a protein complex that's required for the proper segregation of chromosomes.
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Our sincerest appreciation goes out to all postdoctoral fellows during National Postdoc Appreciation Week #NPAW2025 - especially to our fabulous JCC Fellows, past and present!

Congrats to Dr. Saintilnord @wesaint.bsky.social on his recently published review on transposable elements in cancer - check it out!

www.cell.com/trends/genet...

Joan Steitz was awarded the 2018 Special Achievement #LaskerAward for her pioneering discoveries in RNA biology, and her mentorship & support of #WomeninSTEM. 🧪
laskerfoundation.org/winners/lead...
laskerfoundation.org/joan-steitz-...
Find out who will be recognized on September 11th! #Lasker2025

First time at #MLCB! I'll be speaking tomorrow about my development of an ML predictor of domain–peptide interaction affinity to model proteome-scale signaling networks. It'll be livestreamed too.

Cedeño–Rosario and Kaweesa win research award The award honors outstanding early-career scientists studying cancer, infectious disease and basic science.

✨ #TuesdayInspiration

We’re celebrating ASBMB members Luis Cedeño–Rosario & Elizabeth Kaweesa, recipients of the Dr. Eddie Méndez Scholar Award from @fredhutch.bsky.social. This award honors outstanding early-career scientists advancing research.

Congratulations! #ASBMBmembernews
ow.ly/qy1450WU9xk

Congrats Dr. Sinha!!!

#blueskyhandleallstars

ultimately reveal novel therapeutic strategies for delaying or reversing aging-related pathologies. See the link below for more information about Dr. Genuth and her important research.

www.jccfund.org/fellows/#mod... 2/

Naomi Genuth, Ph.D., is a joint Jane Coffin Childs - @hhmi.org Fellow researching the role of protein misregulation during aging. Genuth's studies @berkeleymcb.bsky.social are providing insight into how protein synthesis malfunctions at the molecular, tissue, and organism levels, and may ... 1/

Villar's research scales from protein structure to octopus behavior, and is revealing general principles for the evolutionary fine tuning of signal transduction.

www.jccfund.org/fellows/#mod...
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Pablo Villar, Ph.D. is our current featured fellow. Villar's research @harvardmcb.bsky.social focuses on signal transduction in octopus chemotactile receptors.

Why octopuses 🐙? Because they're awesome and have eight legs (usually), that's why! 1/

Henry's research on ferroptosis will help guide the design of selective cancer therapeutics that leverage this mechanism. Check out The Henry Lab website for more details on their exciting research: thehenrylab.squarespace.com 2/