Frank S. David's Avatar

Frank S. David

@franksdavid.bsky.social

Biotech R&D strategy @ Pharmagellan. Prof of Practice of Biotech @ Tufts Biology. Bio, books, blog & more at www.pharmagellan.com. #biosky

1,143 Followers  |  621 Following  |  291 Posts  |  Joined: 25.07.2023  |  1.9261

Latest posts by franksdavid.bsky.social on Bluesky

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MENA Science | LinkedIn I want to delve into and highlight high-impact research coming out of Arab and North African countries.

Hey, folks -- please show some love/encouragement to a recent Bio MS grad (on the job market!) who's blogging about biomedical research in the Mideast and North Africa: www.linkedin.com/newsletters/...

21.10.2025 16:42 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Hi, folks! I just posted another "links list" of biopharma-relevant stuff that caught my attention (incl. "AI and Alzheimer's cures" -- color me skeptical). mailchi.mp/pharmagellan...

18.09.2025 20:31 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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Measuring Biopharmaceutical Innovation in the Modern Era | The Incidental Economist As the Inflation Reduction Act empowers Medicare to negotiate drug prices based in part on clinical benefit, and as the FDA more closely scrutinizes accelerated approvals, a fundamental question has b...

New essay on measuring biopharma innovation in The Incidental Economist -- led by @sukhunkang.bsky.social; I pitched in: theincidentaleconomist.com/wordpress/me...

14.08.2025 11:21 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Great curated list, @franksdavid.bsky.social -and would have expected no less!

08.08.2025 00:23 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Links: Ph2 failures, pharma innovation, oncology R&D, etc.

My latest "link list": mailchi.mp/pharmagellan...

08.08.2025 00:09 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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How the FDA can score quick wins on transparency Improving how the FDA disseminates already-public information about approved drugs may be unsexy, but it would be a big step toward the era of โ€œradical transparency.โ€

My unsexy but easy suggestion for Marty Makary M.D., M.P.H. on boosting "radical transparency" at the FDA: www.statnews.com/2025/07/29/f...

29.07.2025 11:35 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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You should start a biotech blog A lot of students and young professionals ask me how to get into biotech strategy, consulting, or investing (esp. venture capital).

New (from me): blogging advice for folks who want to get into biotech strategy or finance, incl. resources, examples, and tips to get started: www.linkedin.com/pulse/you-sh...

13.07.2025 22:31 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
AMA: Saloni Dattani
by Toby Tremlett๐Ÿ”น, salonium
Jul 2
1 min read
 1
13
Ask Me Anything
Frontpage
+ Add topic
AMA: Saloni Dattani
Question ideas:
1 comment
Saloni will answer the questions in this AMA between 6-8pm BST on July 8th. Leave your questions as comments, and upvote other questions youโ€™d like to see answered.

If youโ€™ve been around EA for a while, and youโ€™re interested in global health, youโ€™ve probably read Saloni Dattani before.

Saloni writes about global health at Our World In Data and is a co-founder and editor of Works in Progress magazine. Sheโ€™s also recently started a podcast, Hard Drugs, with Jacob Trefethen. She also (somehow) finds time to write a great blog, Scientific Discovery.

Sheโ€™s recently written on:

The decline in cancer mortality, and how itโ€™s not all down to decline in smoking.
How we calculate fertility rates, and why just calculating the total fertility rate leads us astray.
And she delivered a talk at EA Global London on the data that shapes global health.

AMA: Saloni Dattani by Toby Tremlett๐Ÿ”น, salonium Jul 2 1 min read 1 13 Ask Me Anything Frontpage + Add topic AMA: Saloni Dattani Question ideas: 1 comment Saloni will answer the questions in this AMA between 6-8pm BST on July 8th. Leave your questions as comments, and upvote other questions youโ€™d like to see answered. If youโ€™ve been around EA for a while, and youโ€™re interested in global health, youโ€™ve probably read Saloni Dattani before. Saloni writes about global health at Our World In Data and is a co-founder and editor of Works in Progress magazine. Sheโ€™s also recently started a podcast, Hard Drugs, with Jacob Trefethen. She also (somehow) finds time to write a great blog, Scientific Discovery. Sheโ€™s recently written on: The decline in cancer mortality, and how itโ€™s not all down to decline in smoking. How we calculate fertility rates, and why just calculating the total fertility rate leads us astray. And she delivered a talk at EA Global London on the data that shapes global health.

Ask me anything!

If you have questions about writing, podcasting, global health, medical innovation, data, or anything else, I'll be doing an AMA on the EA Forum next week.

It's between 6-8pm BST on July 8th but you can also leave qs here in advance: forum.effectivealtruism.org/posts/i2DtGA...

02.07.2025 09:57 โ€” ๐Ÿ‘ 23    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Links: Chinese biotech, P3 failures, pharma revenue drivers, etc.

Hi, folks -- here's my inaugural "links list" of recent items that caught my eye in biotech R&D and other areas. Please let me know what you think! eepurl.com/jih0E2

02.07.2025 10:17 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Begs the (serious) question: where do โ€œblog postsโ€ fit on that list? Or do they?

20.06.2025 16:25 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Generics FTW.

Also, anyone even mildly interested in drug pricing should read Peter Kolchinskyโ€™s โ€œGreat American Drug Dealโ€.

20.06.2025 16:22 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Good resource for biotech entrepreneurs (HT @wilbanks.bsky.social)

19.06.2025 15:47 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Apparently hope *is* a strategy after all.

endpoints.news/roche-moves-... by @leileiwu.bsky.social of Endpoints

17.06.2025 11:32 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Good piece โ€”>

13.06.2025 16:34 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Great thread โ€” bookmarking for my drug dev class. HT @thewonkologist.bsky.social

13.06.2025 10:54 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Love this โ€” Iโ€™ve sent it to many Tufts Bio students. (So far only 1 has started a blog, but Iโ€™m not giving up.)

12.06.2025 10:04 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
11.06.2025 19:52 โ€” ๐Ÿ‘ 50    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 3

Me: โ€œFIVE hours?โ€

Also me: <hits the โ€œsubscribeโ€ button>

11.06.2025 20:20 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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โ€œFrontiersโ€ and MDPI-pubโ€™d journals are the most common crap citations in my classes (& I explicitly ban them), but Iโ€™ll be on the lookout in case Springerโ€™s โ€œDiscoveryโ€ rears its ugly head.

11.06.2025 11:38 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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I donโ€™t follow the generics market closely, let alone international Gx โ€” so I found this piece by @dereklowe.bsky.social particularly bananas! Go read it. www.science.org/content/blog...

10.06.2025 21:00 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Science writing from the last two years that stuck with me This list consists of writing that ticked two boxes: 1) did I think about the article again more than a week after reading it?, and 2) was it written for a popular audience? So, academic papers, inclu...

Good reading recs here from Jacob Trefethen of Open Phil: blog.jacobtrefethen.com/science-writ...

10.06.2025 13:05 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Valid point

06.06.2025 16:22 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Really interesting post from new Ch Med Ofc of Oura Ring pointing to next steps for device: integration w traditional patient care systems (presumably Epic etc), impact on health behaviorโ€ฆ (in previous role at Apple his expertise included health data interoperabilityโ€ฆ) cc @franksdavid.bsky.social

05.06.2025 22:47 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Or simply: Get lucky: pick winners.

05.06.2025 15:44 โ€” ๐Ÿ‘ 17    ๐Ÿ” 3    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Awesome. Followed closely by the BD strategy of โ€œbuy de-risked late-stage assets, ideally at a bargain priceโ€.

05.06.2025 15:53 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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Good template for a clear paper abstract โ€” HT @johnholbein1.bsky.social (who credits @fgilardi.bsky.social)

05.06.2025 15:50 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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New paper on pharma revenue drivers by IDEA Pharma โ€” hereโ€™s the TL;DR (w/apologies to Michael Pollan; IYKYK):

โ€œSpend on R&D. Not too much. Mostly Phase 3 trials.โ€

www.ideapharma.com/insights/rev...

05.06.2025 15:43 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3

โ€œEvidence-inspiredโ€ โ€” love that! Will def use in future.

05.06.2025 13:56 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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New โ€œHealthspanโ€ whitepaper by the folks at Whoop. Iโ€™m skeptical of these sorts of things but I havenโ€™t read it yet and this isnโ€™t my expertise. Curious to hear thoughts from @dshaywitz.bsky.social and others who follow this area.

www.whoop.com/us/en/theloc...

05.06.2025 12:34 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1

@franksdavid is following 18 prominent accounts