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Excited to announce a new paper out today in @cp-cell.bsky.social discovering RNA mis-splicing derived neoantigens & their cognate T cell receptors (TCRs) as well as characterization of endogenous neoantigen T cells in leukemia patients.
authors.elsevier.com/sd/article/S...
23.04.2025 20:30 — 👍 33 🔁 8 💬 2 📌 0
The full manuscript describing outcomes of 7 days Aza + 7 days Ven in newly diagnosed AML is out!
-72% composite CR rate
-mOS 11.2 months
www.nature.com/articles/s41...
22.04.2025 02:06 — 👍 9 🔁 3 💬 0 📌 0
Age-related blood condition counteracted with a common diabetes drug
Metformin could reduce people’s risk of certain age-associated blood cancers, but more work is needed to identify who is likely to benefit.
New paper from my lab! Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis: rdcu.be/eh1Nb Complementary to new work from Steven Chan & @georgevassiliou.bsky.social as described by @goodell-lab.bsky.social: www.nature.com/articles/d41...
16.04.2025 21:02 — 👍 50 🔁 11 💬 1 📌 2
But also be part of the founding clone of rare cases of tMN
03.04.2025 16:17 — 👍 0 🔁 0 💬 0 📌 0
An unpredictable CHIP mutation that can dramatically expand under alkylating treatment but also spontaneously regress after treatment discontinuation
03.04.2025 16:17 — 👍 0 🔁 0 💬 1 📌 0
Stand-up for science : soutien à la communauté scientifique et universitaire qui se mobilise à Nancy comme ailleurs alors que la liberté académique, la recherche, la science font l'objet d'une attaque sans précédent par Donald Trump et ses alliés.
07.03.2025 17:03 — 👍 20 🔁 5 💬 1 📌 0
Great presentation by @ZhuoerXie showing similar characteristics of #CCUSsm and #MDSsm patients @ash-hematology.bsky.social #ASH24! Proud to be a part of this. @SylvesterCancer @UMiamiHealth @MoffittNews @nih_nhlbi
08.12.2024 01:20 — 👍 6 🔁 1 💬 0 📌 0
Professor & Dattels Family Endowed Chair at The Jackson Laboratory studying hematopoietic stem cell biology, aging & cancer. 🇨🇦 🇺🇸
We are a cancer genetics lab studying functional genomics of blood cancers. We have a special interest in altered RNA processing in cancer.
Assistant Prof at EinsteinMed | studying chromatin biology in lung cancer
lafavelab.org
Oncologist-scientist at Weill Cornell and New York genome center. Into somatic evolution, trees and words
Hematologist 👩🏾⚕️+👩🏾🔬@huntsmancancer @uofuhealth Myeloid leukemias/MPNs. #WomenInSTEM #mpnsm #leusm Northwestern alum 💜 📚🐛 Views are my own
Physician scientist UCLA --> BWH <--> DFCI. Myeloma, CAR-T, CHIP, MDS. LA sports fan stuck in Boston.
Hematologist, Science and Patients Lover. Professor, Dep. of Cancer Pathology, Osaka University🇯🇵
🩸🦴🧬💊🔬🌎⛰️🏃♂️🐭⛩️🇺🇸🗾🫂
MD@Kyoto Univ. → PhD@Univ. of Tokyo. → Pos-doc@Sloan Kettering (NYC) → Junior PI@FBRI (Kobe) → Professor@Osaka.
Physician-Scientist investigating and treating Myeloproliferative Neoplasms and Acute Myeloid Leukemia.
We study the molecular basis of hematopoiesis and heme malignancies @ Fred Hutchinson Cancer Center in Seattle, USA. www.fredhutch.org/en/faculty-lab-directory/lee-stanley.html
Cancer epigenetics; Hematology; Aging.
Cancer, Hematopoiesis, and Stem Cell Researcher
Professor and Chair, Department of Cell Biology, Albert Einstein College of Medicine
Interim Director, Montefiore Einstein Comprehensive Cancer Center
bit.ly/3s3VA1H
steidllab.com
The Goodell Lab. Hematopoietic stem cells, epigenetics, DNA methylation. Houston Texas. Posts are my own.
Heme Chief at Stanford. Physician Scientist studying myeloid malignancies. Views my own.
Hematologist focusing on CLL/SLL, with a side interest in CHIP/CCUS @UC Irvine
We are a cancer epigenetics lab at the Dana-Farber Cancer Institute, Broad Institute and Harvard Medical School.
Our interests include blood cancer development, chromatin biology, splicing and inflammation.
Physician Scientist at MSK. All views expressed here are my own & do not represent my employer. COI:http://bit.ly/2LQCLKe
Leukemia doc and researcher at Moffitt Cancer Center
Leukemia & myeloid malignancy doctor. posts=mine. Repost≠endorsement. He/him. https://scholar.google.com/citations?user=kNhjy-MAAAAJ&hl=en
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