A comparative analysis of the immunotranscriptomic features of DENV-1, -3, and -4 human challenge models https://www.biorxiv.org/content/10.64898/2026.02.17.706422v1
19.02.2026 03:15 โ ๐ 1 ๐ 1 ๐ฌ 0 ๐ 0
@robhagan.bsky.social
Lung caretaker
A comparative analysis of the immunotranscriptomic features of DENV-1, -3, and -4 human challenge models https://www.biorxiv.org/content/10.64898/2026.02.17.706422v1
19.02.2026 03:15 โ ๐ 1 ๐ 1 ๐ฌ 0 ๐ 0We live in a bizarre world where longevity influencers tell millions to take rapamycin, sit in hyperbaric oxygen chambers, blast themselves with red light therapy, and take 50+ supplements daily. Meanwhile something that cuts dementia risk by 20% Is invisible.
open.substack.com/pub/overmatt...
I am an Epic Chat conscientious objector (ICU, not ID) for 2 reasons. 1- It is a constant interruption. 2- Communication (big C) is important and Epic Chat is usually low quality (little c) communication. If someone needs to talk to the ICU there are many ways and Epic Chat is not the right one.
18.02.2026 11:15 โ ๐ 1 ๐ 0 ๐ฌ 1 ๐ 0Don't give up!
13.02.2026 19:34 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0On the one hand, I think it's great that someone mapped Bluesky users. On the other hand, I'm a bitworried that I map at some kind of Lagrange point between "Biomedical Research Scientists" (totally makes sense) and..."Brazilian Young Adults on Bluesky". Where's the cycling group?
09.02.2026 14:59 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0Jeff Bezos clarifies that newspapers also die in darkness
News In Photo:
05.02.2026 15:21 โ ๐ 224 ๐ 43 ๐ฌ 8 ๐ 4I like my thylakoids the way I like my pancakes:
Stacked so densly it causes iridescence and apprears blue when lit at the right angle.
Honestly. There is no easy fix to <waves in GenX> alla this. But a starting place could be to address the CRIME of Citizens United. Corporations are NOT people. Money is NOT speech. And the place we're in right now? Owes a LOT to those two things being perverted by Citizens United.
21.01.2026 18:37 โ ๐ 1993 ๐ 445 ๐ฌ 55 ๐ 15We've got ISSUES. Literally.
We scraped >100k special issues & over 1 million articles to bring you a PISS-poor paper. We quantify just how many excess papers are published by guest editors abusing special issues to boost their CVs. How bad is it & what can we do?
arxiv.org/abs/2601.07563
A ๐งต 1/n
How does SARS-CoV-2 infection lead to dysregulation of the immune system in severe and #LongCovid?
An unanticipated mechanism described @pnas.org with depletion of specific immune T and dendritic cells, open-access
www.pnas.org/doi/suppl/10...
There must be an ICU snack that treats the headaches.
01.01.2026 19:12 โ ๐ 2 ๐ 0 ๐ฌ 0 ๐ 0Spicy kimchi on baked potato.
25.12.2025 20:25 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0As with Shakespeare, I always found myself coming out of a Stoppard play feeling more intelligent than when I went in.
02.12.2025 15:02 โ ๐ 42 ๐ 5 ๐ฌ 0 ๐ 0A display of cheeses. Two in the front are vaguely torus shaped, sliced in half so you can see the shape, like a bagel cut in half to make two u-shapes. They look like drawings of the disk of matter around a black hole, narrow in the middle and flared on the outside.
For the astronomers: I found an accretion disk diagram cheese. A quesar.
20.11.2025 12:47 โ ๐ 608 ๐ 74 ๐ฌ 22 ๐ 10A screen shot of the antibiotic personality quiz
Itโs World AMR Awareness Week, and this year I had the honor to re-imagine and doodle the antibiotics in the antibiotic personality quiz ๐๐๏ธ
Thank u @brxad.bsky.social for this amazing and fun opportunity!
Cโmon, take the quiz, itโs a #WAAW tradition ๐๐
#IDSky
quiz.tryinteract.com#/59e68e3a8ec...
My residency director used to say never have more than 2 if you're on call.
11.11.2025 16:42 โ ๐ 2 ๐ 0 ๐ฌ 1 ๐ 0It is not often that a new flow cytometry protocol makes the newspaper! I also got a kick out of seeing our science tagged as "quirky"!
www.cambridgeindependent.co.uk/news/fairy-l...
Nature suggests you use their "Manuscript Adviser" bot to get advice before submitting
I uploaded the classic Watson & Crick paper about DNA structure, and the Adviser had this to say about one of the greatest paper endings of the century:
New - my first piece for @science.org !
Absolutely crazy footage of rat behaviour in Germany.
Rats filmed snatching bats from air for first time | Science | AAAS share.google/WAsAIQ8j0MKp...
An alien fleet appeared in Earth's orbit, and broadcast a message:
"Having studied you furtively, we now seek formal contact, and want to meet your greatest thinkers..."
A long list followed.
"How do we tell them?" world leaders wondered.
Topping the list were the names Calvin and Calvin's Dad.
Vital AF is the MICU vibe.
09.10.2025 11:39 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0- calendar makes no sense
- half the riders and half the teams in most races don't influence the outcome
- Giro and Vuelta should be 2 weeks
Researchers in #ScienceSignaling have mapped out the genetic and proteomic effects of a protein named MYC that is intimately linked to cancer growthโa discovery that could lead to new therapies aimed at this โundruggableโ target. https://scim.ag/4nuQB1R
02.10.2025 15:29 โ ๐ 24 ๐ 8 ๐ฌ 0 ๐ 0For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper?
You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
Fox
Emily Kewageshig ~ Anishinaabe
2021
The drosophila Dscam1 gene presumably evolved specifically to mess with bioinformaticians
15.09.2025 19:41 โ ๐ 7 ๐ 1 ๐ฌ 0 ๐ 0The Vuelta is a marshmallow. After the meal of the TdF, you neither want it nor need it. When you try it, it's briefly more enjoyable than you anticipated. And then you forget it ever happened. And then the next time you do it again.
15.09.2025 01:13 โ ๐ 0 ๐ 0 ๐ฌ 0 ๐ 0I keep staring at this video showing the movement of aerosols in the atmosphere. It's so mesmerizing! That and more of the best from @science.org and science in this edition of #ScienceAdviser: www.science.org/content/arti... ๐งช
15.08.2025 16:22 โ ๐ 87 ๐ 30 ๐ฌ 3 ๐ 1Some people ride bikes for fitness, and others for transportation.
Some ride for _______
๐ ?