Matt Patton

@bmj.com Please look at PubPeer comments on an article you published last week. pubpeer.com/publications...
I think your research integrity dept shld act swiftly on this one, given clinical significance.
I'm aware of even more evidence of problems so let me know if this is not sufficient.

Opinion | A Journal Promised to Retract a Flawed Autism Study. It's Still Online. Junk science leaves an indelible mark

hopeless autism study still up in J Pers Med despite
promise to retract it www.medpagetoday.com/opinion/seco...
This is how @mdpiopenaccess.bsky.social pollutes the literature with junk

Eye-opening work on heterogeneity among depression scales. Also, I’m a pluralist and everything, but … do we need 27 youth depression scales? Why have researchers not updated and further developed them? What does this say about the state of our field?

an oscar statue with the words " and the oscar goes too " on the bottom ALT: an oscar statue with the words " and the oscar goes too " on the bottom

Can’t wait! My money is on Hard Drugs winning highest standard deviation for episode length. ;-)

University investigations feel like legal risk management exercises. Investigations need to be commissioned by professional associations who have a stake in the credibility of their field’s scientific record.

How do you suppose the global homicide rate has changed over the last quarter century? (Hint: Another example of good things happening in our seemingly depressing world.) data.worldbank.org/indicator/VC...

False hope, fabricated data: No public notice after UBC uncovered serious misconduct in medical study | CBC News A celebrated Vancouver researcher used fabricated data and hid evidence of infected wounds to falsely claim his patented skin treatment could heal years-old bed sores in a matter of weeks, according t...

Another example of institutional investigations conducted in secret, without a public report, for 'privacy reasons'.

Investigation found UBC researcher fabricated data, gave spinal patients 'false hope.' The public was not told.

www.cbc.ca/news/canada/...

#OAweek Support diamond #openaccess scholar-controlled journals, such as those listed at freejournals.org.

Serial Ketamine Infusions for Depression This randomized clinical trial evaluates outcomes following adjunctive ketamine infusions vs midazolam for depression.

New 6-month depression RCT in n=65, serial Ketamine infusions as adjunctive care vs active placebo midazolam.

Ketamine did not outperform primary nor any of the secondary efficacy, cognitive, economic, or quality-of-life outcomes.

🧪 #psychiary #PsychSciSky

jamanetwork.com/journals/jam...

In a new Editorial, Historical Biology promotes preregistration, Registered Reports, @pci-regreports.bsky.social and PCI-Paleonotology, and a three year plan to move to open and FAIR data standards.

A forward-looking approach by @drmarkyoung.bsky.social.

www.tandfonline.com/doi/pdf/10.1...

@briannosek.bsky.social

Tune in to find out:

- how to go from hallucinated cat pictures to hallucinated proteins
- whether @jacobtref.bsky.social can do photosynthesis
- whether we can make tiny protein straws for tardigrades to drink from

I confess to not getting it as a citizen of a republic (such as it is). Was this Andrew guy like Count of Keeping Kids Safe or something?

YouTube video by Works in Progress The art of protein design with AI

New episode of Hard Drugs!

What if you could design a protein never seen in nature?

Scientists are using new AI tools like RFDiffusion, AlphaFold & ProteinMPNN to hallucinate novel proteins to solve problems nature hasn't.

@jacobtref.bsky.social & I talk about the art of protein design 🧑‍🎨

Your Genes Are Simply Not Enough to Explain How Smart You Are Seven years ago, I took a bet with Charles Murray about whether we’d basically understand the genetics of intelligence by now.

In 2018, Charles Murray challenged me to a bet: "We will understand IQ genetically—I think most of the picture will have been filled in by 2025—there will still be blanks—but we’ll know basically what’s going on." It's now 2025, and I claim a win. I write about it in The Atlantic.

Happy birthday, Saloni! 🎂🥳❤️

I’ve been giggling about this meme all day lol

What's new in biology: October 2025 Safer transplants, new antibiotics, the rise of paper mills, long-term flu protection, slowing down ageing, and more.

New post!

• Transplants could be safer, without needing immunosuppressives
• AI models and a LOT of filtering created a new antibiotic
• Paper mills are rising
• A long acting antiviral for flu?
and more.

I've written another round up of news in biotech and medicine with @nikomccarty.bsky.social

Excellent detailed intro paper on open scholarship in clinical psychology by some of my favourite authors on the topic, including @drlynam.bsky.social @dsbarra.bsky.social @jnfrltackett.bsky.social @aidangcw.bsky.social @jdmiller.bsky.social and others. Perfect paper to turn into an intro lecture!

So a spurious correlation from an observational study is “gold standard science”, but testing vaccines in multiple RCTs with over 30,000 participants each is not?

I don’t understand why it takes so long after you’ve written for it to come out. They’re as bad as Nature.

Measles vaccines save millions of lives each year Measles once killed millions every year. Vaccines changed this, preventing disease, long-term immune damage, and deadly outbreaks.

Your regular reminder that measles vaccines are the most lifesaving childhood vaccine in the schedule, and save over a million lives globally per year.

ourworldindata.org/measles-vacc...

100 years of insulin in 15 minutes

New podcast episode of HARD DRUGS!

A hundred years ago, insulin was scraped from pig pancreases.
Today, it’s made by bacteria in giant tanks.

In this episode, we cover 100 years of insulin … in 15 minutes!

89 of my journal articles were used to train Meta’s AI. You can alert the lawyers handling the class action suit if your intellectual works were used as well at www.anthropiccopyrightsettlement.com.

Pleased to learn that my department will be changing the name of the "Dissertation Defense" to the "Dissertation War"

Still there so far.