Lizzie Coulson

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🚨 New WP! 📄 "Publish or Procreate: The Effect of Motherhood on Research Performance" (w/ @valentinatartari.bsky.social
👩‍🔬👨‍🔬 We investigate how parenthood affects scientific productivity and impact — and find that the impact is far from equal for mothers and fathers.

A neuroscientific model of near-death experiences - Nature Reviews Neurology Near-death experiences (NDEs) are episodes of disconnected consciousness that typically occur in actual or perceived life-threatening situations. This Review discusses the mechanisms that might underl...

A neuroscientific model of near-death experiences

Near-death experiences are episodes of disconnected consciousness that occur when you are on the brink of death. These experiences are characterized by rich content and prototypical mystical characteristics.

1/2

www.nature.com/articles/s41...

I can’t recommend this enough.

UNBREAKING, a new project from @lizneeley.bsky.social & co, documents & explains our many concurrent institutional collapses.

It’s beautifully executed work, full of intellectual & moral clarity. 3 pages are live, more will come. It’s SO GOOD, & I learned so much.

I Was Considered A Nobody Katalin Karikó was ignored, demoted, and dismissed for decades. Then she won a Nobel Prize.

Dr. Katalin Karikó spent decades experimenting with mRNA. She was scoffed at, demoted, and eventually forced to retire. Then, she won a Nobel Prize.

Her story is the first in our 10-episode series, “The Leap,” produced with the Hypothesis Fund.

Fornix subdivisions and spatial learning: a diffusion MRI study https://www.biorxiv.org/content/10.1101/2025.05.15.654313v1

A&D: Translational Research & Clinical Intervention article defines true progress in clinical trials as prioritizing meaningful, patient-centered outcomes like survival, symptom relief and quality of life #TRCI #AlzResearch

alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Text reads I advocated for basic science. #ScienceServesUsAll. The background is a 3D illustration protein enzymes.

Why we advocate: “Without basic research...we won’t have new drugs, cutting-edge innovations, or the knowledge we need to address the challenges of the 21st century.”
—Sarina Neote
www.asbmb.org/asbmb-today/...
Take action. Write to your lawmaker: asbmb.quorum.us/campaign/123....
#ScienceServesUsAll

Dr. Karikó's journey is a powerful example of the kind of science we support at The @hypothesisfund.bsky.social: bold, curiosity-driven research pursued despite the odds.

✨ Listen to her incredible story in the 1st episode of The Leap - available now! 👇

Cholinergic blockade reveals role for human hippocampal theta in encoding but not retrieval https://www.biorxiv.org/content/10.1101/2025.05.12.653487v1

How can cerebral vascular changes be predicted in patients with cognitive decline?

Check out this recent Alzheimer’s and Dementia article about specific blood biomarkers linked to vessel health and cognitive outcomes #AlzResearch

alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

The great brain clearance and dementia debate An established theory for how good sleep reduces a person’s risk of neurodegenerative disease has been called into question. The ensuing argument could have enormous consequences for the treatment of ...

The debate on the glymphatic system and sleep gets top teir commentary. www.nature.com/articles/d41...

we're crowd-sourcing a searchable repository of tangible benefits stemming from federally-funded research. Come enjoy the great stories; or send in an idea; or volunteer to join the team.

publicusaresearchbenefits.com

please share and re-share so we get more great stories in there!

The tragic outcome of forcing universities to rely on foreign students to subsidise everyone else, making them vulnerable to an outside shock (like Brexit).

How do clinical and preclinical researchers view the promise and limits of new Alzheimer’s treatments?

Neuro Current Ep. 36 brings together differing perspectives on emerging #Alzheimers therapies.

🎧Listen: www.jneurosci.org/podcast
📺 Watch on demand: neuronline.sfn.org/scientific-r...

Very interesting to think about cooperation vs skill in the task in parter choice

Anticipating a great time as the ASBMB meeting Chicago this week

Factors associated with true‐positive and false‐positive diagnoses of behavioural variant frontotemporal dementia in 100 consecutive referrals from specialist physicians Background The behavioural variant of frontotemporal dementia (bvFTD) is a challenging diagnosis due to overlapping symptoms with psychiatric and other neurological conditions. Accordingly, misdiagn.....

Our latest study highlighting a bunch of factors to consider that could improve diagnostic accuracy in Frontotemporal Dementia.

onlinelibrary.wiley.com/doi/10.1111/...

Non-linear and time-domain sleep qEEG features predict CSF protein damage markers in early Alzheimers disease #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.03.28.645905v1

This is a very significant statement from 1,900 leading scientists writing to the public to highlight the catastrophe of the current US adminstration's actions:

Administration is weakening U.S. research cap | EurekAlert! www.eurekalert.org/news-release...

Will you be at #ADPD2025 in Vienna?

Meet the @alzassociation.bsky.social Alzheimer's and Dementia journal family editors and publishers!

Come by and ask your submission and publishing questions!

#AlzResearch

Researchers find a hint at how to delay Alzheimer's symptoms. Now they have to prove it An experimental treatment appears to postpone Alzheimer's symptoms in some people genetically destined to get the disease at a young age.

Promising though preliminary new research finds that a drug that removes beta-amyloid plaques — a hallmark of Alzheimer’s — from the brain may delay onset of the disease. Learn more: bit.ly/4l6Zzlq.

Combination of Cas9 and adeno-associated vectors (AAVs) enables efficient in vivo knockdown of precise miRNAs in the rodent brain https://www.biorxiv.org/content/10.1101/2025.03.26.645225v1

The role of cerebrovascular reactivity on brain activation during a working memory task in type 2 diabetes INTRODUCTION Impaired cerebrovascular reactivity (CVR) is common in type 2 diabetes (T2D) patients and is a risk factor for dementia. However, most prior functional magnetic resonance imaging (fMRI)...

How is cerebrovascular reactivity in type 2 diabetic (T2D) patients associated with dementia risk?

Using a working-memory fMRI task, cerebrovascular reactivity was found to be related to brain activation in T2D patients #DADM

Full article:
alz-journals.onlinelibrary.wiley.com/doi/full/10....

When Dwarf Lemurs Hibernate, Their Chromosomes Do Something Odd The ends of chromosomes, called telomeres, typically shorten as an organism ages. But when some fat-tail dwarf lemurs hibernate, they lengthen.

These sleeping cuties undergo an unusual process while they hibernate in winter. Dr. Marina Blanco and Dr. Lydia Greene join us to discuss the recent findings.

a car driving on a road with "PhD ahead" on a road sign in view.

Read Now: Your Roadmap to PhD!

Use this guide from @abigailbowring.bsky.social to learn the soft insights and hard facts to consider when deciding if a PhD is right for you: bit.ly/3XY3N4I

Why Walking Helps Us Think Since at least the time of Greek philosophers, many writers have discovered a deep, intuitive connection between walking, thinking, and writing.

Since at least the time of Greek philosophers, many writers have discovered a deep, intuitive connection between walking, thinking, and writing.

It’s been amazing to see this grow

Watching axons on the move

Check out this study, ranked ‘Fundamental’, on how the ligand Netrin mediates axon guidance through haptotaxis and chemotaxis.
elifesciences.org/articles/100...

“Every dollar spent on the NIH produces additional commercial activity of various kinds that help our country become wealthier, not poorer.”

In today’s episode, we speak with a former director of the NIH about the institutes’ future in the face of government cuts.

Listen here 🎧: pod.link/73329284/epi...