Matthias Ernst

We use teflon tubing for water critical parts before the chiller.

So why did they change it? Is it cheaper?

We sometimes make liqueur or chutney out of them. But yes it was more than I expected.

I just made 45 jars of quince jelly but with a steam juicer. Our tree in the garden had almost 30 kg of quince. We never had so many before.

While roaming in Paris, you can typically use all available networks while at home you can only use one. Therefore it is likely that the coverage provided by all networks is better.

The new AMPERE Bulletin for fall 2025 has been published with reports from conferences, reports from the Bureau and Committee meeting and other information. Download from www.ampere-society.org/bulletins/Am...

But the worst problem are devices that rely on external servers. Because there is never a guarantee that they will be supported for more than the lifetime of the current management. I avoid them at almost all costs.

I agree, this is a problem but probably not for washing machines/dryers/fridges and stuff like this. They might not get new features but usually this is not a problem. TVs are different since they have to interact with the outside.

Why would you connect a fridge to the WIFI?

"High field" is in the same league as (ultra-)fast MAS.

ENC 2026 banner

Call for nominations, the 2026 Günther Laukien Prize @enc-conference.org to recognize cutting-edge experimental NMR enabling beneficial new applications, supported by @brukercorporation.bsky.social Nominations deadline is October 31 www.enc-conference.org/Gunther-Lauk... #NMRchat 🧲

Why?

When performing spin dynamics simulations under MAS, it is necessary to do 3-angle averaging. Conventionally this is done with 2-angle averaging and a gamma-carousel average. We show that this convention should be avoided in favor of proper integrated 3-angle averaging.
doi.org/10.1016/j.jm...

Spezi - Wikipedia

Mezzo Mix is a brand name. The generic name (at least in southern Germany) which is also a trade name to make things complicated is Spezi.

en.wikipedia.org/wiki/Spezi

Gibt es da eigentlich genauere Informationen was gemacht wurde und was passiert ist, dass die Bauarbeiten nicht abgeschlossen werden konnten?

Bumps on the Road: The Way to Clean Relaxation Dispersion Magic-Angle Spinning NMR Microsecond-to-millisecond motions are instrumental for many biomolecular functions, including enzymatic activity and ligand binding. Bloch-McConnell Relaxation Dispersion (BMRD) Nuclear Magnetic Resonance (NMR) spectroscopy is a key technique for studying these dynamic processes. While BMRD experiments are routinely used to probe protein motions in solution, the experiment is more demanding in the solid state, where dipolar couplings complicate the spin dynamics. It is believed that high deuteration levels are required and sufficient to obtain accurate and quantitative data. Here we show that even under fast magic-angle spinning and high levels of deuteration artifactual “bumps” in 15N R1ρ BMRD profiles are common. The origin of these artifacts is identified as a second-order three-spin Mixed Rotational and Rotary Resonance (MIRROR) recoupling condition. These artifacts are found to be a significant confounding factor for the accurate quantification of microsecond protein dynamics using BMRD in the solid state. We show that the application of low-power continuous wave (CW) decoupling simultaneously with the 15N spin-lock leads to the suppression of these conditions and enables quantitative measurements of microsecond exchange in the solid state. Remarkably, the application of decoupling allows the measurement of accurate BMRD even in fully protonated proteins at 100 kHz MAS, thus extending the scope of μs dynamics measurements in MAS NMR.

Our latest publication in @jacs.acspublications.org is out: pubs.acs.org/doi/10.1021/...
We show clean ways to probe dynamics on microsecond time scales by relaxation-dispersion MAS #NMR. Microsecond motions are often essential for function e.g. in enzymes.
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Do you want to learn about all relevant aspects of biomolecular solid-state NMR, from theory to application?

Join the 10th European Solid-State NMR Summer School❗️

🗓️ October 20-24, 2025 | Garching, Germany

📌 Application Deadline: 01.09.2025

www.bio.nat.tum.de/ocb/upcoming...

#NMRchat #BioNMR

#NMRchat Bumps on the Road: The Way to Clean Relaxation Dispersion Magic-Angle Spinning NMR http://dx.doi.org/10.1021/jacs.5c09057

Bumps on the Road: The Way to Clean Relaxation Dispersion Magic-Angle Spinning NMR Microsecond-to-millisecond motions are instrumental for many biomolecular functions, including enzymatic activity and ligand binding. Bloch-McConnell Relaxation Dispersion (BMRD) Nuclear Magnetic Reso...

Bumps on the Road: The Way to Clean Relaxation Dispersion Magic-Angle Spinning NMR, Ben P. Tatman*, Vidhyalakshmi Sridharan, Motilal Uttarkabat, Christopher P. Jaroniec, Matthias Ernst, Petra Rovó, Paul Schanda* pubs.acs.org/doi/10.1021/... #NMRchat 🧲

An example is when you do polarization transfer and only one of the exchanging species is generated for whatever reason.

If the initial state at the start of the experiment is not the equilibrium state and the system evolves towards the equilibrium. I am not sure what your experiment was.

#bioGUNE_Talent | 👏 Óscar Millet #CICbioGUNE @brtaeus.bsky.social, appointed Vice President of @group-ampere.bsky.social, Europe’s top #NMR organization, the first Spanish scientist to hold this role

🎉 Congratulations, Óscar!

🔗 ow.ly/hxi450Wuwiw

In the open review process at @group-ampere.bsky.social 's Magnetic Resonance journal, the Discussion about an analysis of the carbon footprint of NMR conferences is still open for a few days.
mr.copernicus.org/preprints/mr...
Feel free to leave a comment there!

If you have a non-equilibrium situation at the start, something like this can happen. But it would give you only cross peaks on one side of the diagonal.

ETH Zürich has been recycling helium at least since the early 80s for low-temperature experiments as well as for NMR magnets.

Work by my student Gevin von Witte:

Temperature-Dependent Dynamic Nuclear Polarization of Diamond | The Journal of Physical Chemistry C pubs.acs.org/doi/10.1021/...

summer school poster

10th Ampere Biological Solid-State NMR Summer School, October 19-24, 2025, the Technical University Munich (TUM) Garching, Germany, under the auspices of @group-ampere.bsky.social www.bio.nat.tum.de/ocb/upcoming... #NMRchat #NMR 🧲

Quantifying the carbon footprint of conference travel: the case of NMR meetings Abstract. Conference travel contributes to the climate footprint of academic research. Here, we provide a quantitative estimate of the carbon emissions associated with conference attendance by analyzi...

Read our preprint related to an important topic: climate change 👉 mr.copernicus.org/preprints/mr...
As scientists, we rely on data for rational decisions. Climate science is clear: human-made CO₂ emissions are changing our climate fast. But what can we do about it—individually or as a community? 1/n