James Gahan

Group Leader - Genome Biology Unit Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...

To all post-docs: The Genome Biology dept ‪@embl.org
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Transitions in development – an interview with Jeffrey Farrell

@jeffreyafarrell.bsky.social talks about becoming a group leader, his insights on advocacy for developmental biology and his belief in unifying single-cell biology with classical approaches.

journals.biologists.com/dev/article/...

Repressive cytosine methylation is a marker of viral gene transfer across divergent eukaryotes Abstract. Cytosine DNA methylation patterns vary widely across eukaryotes, with its ancestral roles being understood to have included both transposable ele

Happy to see our latest work out in @molbioevol.bsky.social. We revisit the evolution of 5-methylcytosine across neglected eukaryotic supergroups, establishing an ancestral repressive role silencing genome invaders, both transposons and viral elements👾: academic.oup.com/mbe/advance-... 🧵 1/7

CRISPR-Cas9 genome editing in Corallochytrium limacisporum,a key species for understanding animal origins | Open Biology Microbial holozoans are the closest unicellular relatives of animals. They share a substantial gene repertoire with animals and exhibit complex life cycles. Studying these organisms is crucial for und...

✨Animal evolution fans, rejoice! CRISPR-Cas9 is now in Corallochytrium ready to unlock secrets of animal origins! 🔬Led by @patriciasuarez.bsky.social & @sebasn1.bsky.social
royalsocietypublishing.org/doi/10.1098/... @royalsociety.org @ibe-barcelona.bsky.social#holozoans #ProtistsonSky

Great opportunity! The Uni Vienna has launched a call (APART) for 4-funding for outstanding postdocs from a US institution. The host lab has to nominate by 1 August a candidate for further selection. Anyone interested in our work please contact me by email with CV/motivation letter. Hurry up!

CRISPR-Cas9 genome editing in Corallochytrium limacisporum,a key species for understanding animal origins | Open Biology Microbial holozoans are the closest unicellular relatives of animals. They share a substantial gene repertoire with animals and exhibit complex life cycles. Studying these organisms is crucial for und...

Very happy to share our new paper where we develop CRISPR-Cas9 genome editing in our favorite unicellular relative of animals, Corallochytrium limacisporum! With @sebasn1.bsky.social @multicellgenome.bsky.social Elena and Claudio.

Check it out:
royalsocietypublishing.org/doi/10.1098/...

🚨🚨🚨

Please RT!

We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets.

Deadline: 30/09/25👇

Very cool to see you will work on Oikopleura!

📢 We are recruiting!
Several projects are available and can be tailored to the candidate's profile. Most include confocal imaging/spatial OMICs technologies.
Please share and RT 🙏

Very excited to share the first preprint of the lab! We show that the nuclear pore protein TPR forms biomolecular condensates which keep heterochromatin away from the nuclear pore complexes and maintains global chromatin organization. Check it out, share it, tell us what you think!!

Evolution and origins of multicellularity across the tree of life The study of the origins and evolution of multicellularity in different lineages has recently captured the attention of many research groups and is fueling the generation of numerous innovative resea…

If you missed the deadline and couldn't register or send an abstract, but still want to attend online this nice workshop, you still have time! Until September 5th. Don't miss this opportunity. @ibe-barcelona.bsky.social @embo.org @prbb.org

meetings.embo.org/event/25-mul...

Evolution and origins of multicellularity across the tree of life The study of the origins and evolution of multicellularity in different lineages has recently captured the attention of many research groups and is fueling the generation of numerous innovative resea…

Learn about the origins and #evolution of #multicellularity at EMBO Workshop "Evolution and origins of multicellularity across the tree of life" in Barcelona, Spain, 9–11 October.

Registration deadline: 20 July

meetings.embo.org/event/25-mul...
#EMBOmulticellularity #EMBOevents 🧪

We are looking for a student to continue our work on chromatin evolution:
www.nature.com/articles/s41...
www.biorxiv.org/content/10.1...

The project with @seanamontgomery.bsky.social will focus on chromatin state readers across eukaryotes.

More info: recruitment.crg.eu/content/jobs...

We are looking for new colleagues to come join us in Galway as group leaders (Junior and Senior). The Centre for Chromosome Biology is a great place and it is a good time to join. Please reach out if you want to chat about the opportunity!
www.nature.com/naturecareer...

Engineering yeast multicellular behaviors via synthetic adhesion and contact signaling By designing synthetic toolkits for contact-based signaling (MARS) and cell-cell adhesion (SATURN), we program yeast to form multicellular structures and perform complex tasks, like building logic cir...

Online now @ Cell is the yeast multicellular engineering paper from Fankang Meng - the fruits of his productive PhD in our group. He developed modular synthetic biology tools to bring multicellular behaviours to yeast - specific adhesion, juxtacrine signalling and more. www.cell.com/cell/fulltex...

Celebrating 10 years of our lab with a new preprint:
www.biorxiv.org/content/10.1...
How does enhancer location within a TAD control transcriptional bursts from a cognate promoter?
Experiments by Jana Tünnermann and modelling by Gregory Roth

I am very happy to have posted my first bioRxiv preprint. A long time in the making - and still adding a few final touches to it - but we're excited to finally have it out there in the wild:
www.biorxiv.org/content/10.1...
Read below for a few highlights...

Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression Zinc finger proteins (ZNFs) are the largest family of transcription factors, yet how they activate gene expression remains unclear. In this study, we identified Zincore, a protein complex consisting o...

In today’s publication in Science we introduce Zincore: a novel protein of QRICH1 and SEPHS1 and functions as a transcriptional coregulator dedicated to zinc finger transcription factors. Here’s how we found it: 🧵 www.science.org/doi/10.1126/... 1/11

Decoding cnidarian cell type gene regulation https://www.biorxiv.org/content/10.1101/2025.07.01.662323v1

Our new paper on structure and growth of Porpita porpita - rdcu.be/etcY6 . Like Velella and Physalia, this is a colonial cnidarian that floats at the surface of the Ocean. The whole colony arises form a single embryo through clonal growth that gives rise to many specialized bodies.

Excited to share our new work on the 3D architecture of the ctenophore aboral organ!

We explored its remarkable cellular diversity and integration with the syncytial nerve net, uncovering connectivity and insights into the evolution of sensory complexes.

www.biorxiv.org/content/10.1...

Can’t recommend this enough! @msarscentre.bsky.social is a great place to do science and Bergen is also well worth a visit!

new preprint alert from the lab: bringing some order into the wide and wild diversity of archaeal histones. Who has acidic histones? who has multiple histones? what histone combinations do archaea employ and why? find all of this and more here
www.biorxiv.org/content/10.1...

Call for 20 Assistant Professor positions Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce...

Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages.

ki.se/en/about-ki/...

Congratulations @annaferraioli.bsky.social and all the authors, really cool work!

Our new paper is out: "The 3D architecture of the ctenophore aboral organ & the evolution of complex integrative centers in animals.

We reveal a remarkable cell type diversity, nerve net condensation, a multilayered circuit & gene expression profiles.

www.biorxiv.org/content/10.1... #ctenophores

Congratulations to five researchers at University of Galway who have been awarded more than €3.2m funding from @researchireland.ie Pathway programme in a special investment in projects aligned with national priorities. 🙌🎉

Very happy to support someone in applying for a MCSA fellowship to work on either choanoflagellates or Nematostella! If you have a competitive CV then get in contact!

marie-sklodowska-curie-actions.ec.europa.eu/actions/post...

🚨We are looking for post-doctoral candidates to apply for a MSCA fellowship.

Projects on gene regulation in neural development or neurdegenerative diseases using single-cell omics.

Computational & wet-lab candidates are welcomed! #postdoc #MSCA #Barcelona #singlecell.

The Frank lab here in Galway are looking for a new PostDoc to join them...I cant recommend this enough so, if you are looking for a position, contact Uri!