Vicente Pérez-García

Looking to pursue cutting-edge research in early development, maternal-fetal interaction, or placental biology? See 👇

- Funded PhD www.trophoblast.cam.ac.uk/phd-students...
- Next Generation Fellowship www.trophoblast.cam.ac.uk/next-generat...
- MPhil www.mphil.bio.cam.ac.uk/mphil-pathwa...

02.10.2025 08:15 — 👍 9    🔁 14    💬 0    📌 2

2 weeks left to apply! Fully-funded 4-year PhD studentships for home or overseas students, applications open till 4 November. 🔗 Please like and share to spread the word! www.trophoblast.cam.ac.uk/phd-students...

Take a look at projects for 2025/26 www.trophoblast.cam.ac.uk/opportunitie...

20.10.2025 15:43 — 👍 4    🔁 2    💬 0    📌 0

Feto-placental blood vessel development Summary: This Review contains an overview of placental vascular development and pathologies in mice and humans and highlights key remaining questions in the field.

Very happy to share I've written a review on placental vascular formation in mice and humans, now published in @dev-journal.bsky.social.

journals.biologists.com/dev/article/...

@idrm.ox.ac.uk Funded by the @thebhf.bsky.social

02.06.2025 10:24 — 👍 17    🔁 6    💬 1    📌 0

✳️ Join us for this week's interesting #CiMUSSeminar with guest speaker @vpglab.bsky.social from @cbm-csic-uam.bsky.social.

Dr. Vicente Pérez explores novel therapies for pregnancy disorders & cancer

Hosted by PI @mobilegenomes.bsky.social mes.bsky.social

#RedeCIGUS #FondosEuropeos @usc.gal

02.04.2025 09:01 — 👍 5    🔁 2    💬 0    📌 0

orange and cyan microscopy image of cartilage tissues

Using #CRISPR/Cas9 to genetically modify cells to produce extracellular matrices with altered compositions.
elifesciences.org/reviewed-pre...

23.03.2025 21:01 — 👍 17    🔁 4    💬 0    📌 0

Check out these feather buds on the chicken embryo's wing! Our latest study @plosbiology.org reveals that temporary inhibition of sonic hedgehog signalling transforms feathers into simple, protofeather-like structures—similar to those of their dinosaur ancestors🔬🦖🧪

journals.plos.org/plosbiology/...

21.03.2025 10:06 — 👍 118    🔁 37    💬 6    📌 4

Zika virus NS1 drives tunneling nanotube formation for mitochondrial transfer and stealth transmission in trophoblasts - Nature Communications Michita et al. show that Zika virus (ZIKV) NS1 induces tunneling nanotubes (TNTs) in placental cells, which facilitate viral spread and transport of mitochondria in placental cells. Infection with a NS1 mutant ZIKV not inducing TNTs results in a higher interferon response than wild-type ZIKV infection.

A study in Nature Communications shows that Zika virus NS1 induces tunneling nanotubes in placental cells, which facilitate viral spread and transport of mitochondria in placental cells. The findings could be used to develop therapeutic strategies targeted against this transmission mode. 🧪

01.03.2025 14:32 — 👍 43    🔁 13    💬 1    📌 1

JCI Insight - Treg cells promote decidual vascular remodeling and modulate uterine NK cells in pregnant mice

Our new paper linking Tregs, uNK cells & uterine vasculature “Treg cells promote decidual vascular remodeling and modulate uterine NK cells in pregnant mice” super effort from Alison Care, Shanna Hosking, Lachlan Moldenhauer and all the team! insight.jci.org/articles/vie...

24.01.2025 23:24 — 👍 12    🔁 2    💬 0    📌 1

Descifran un mecanismo clave para el desarrollo de la placenta, basado en la metilación del ADN placentario - Centro de Biología Molecular Severo Ochoa La expresión de los genes es el proceso mediante el cual la información contenida en el material genético se utiliza para producir proteínas, que a su vez realizan una función […]

www.cbm.uam.es/index.php/20...

16.01.2025 07:07 — 👍 0    🔁 0    💬 0    📌 0

Applications are open for our Caregiver Travel Grant 2025! Apply now for a chance to receive flexible funding to cover caregiving expenses while attending an in-person scientific conference! Apply: www.mothersinscience.com/caregiver-tr... 📅 Deadline: March 31, 2025 #WomenInSTEM #STEMM #AcademicMama

10.01.2025 10:13 — 👍 17    🔁 16    💬 0    📌 2

Ectopic expression of DNMT3L in human trophoblast stem cells restores features of the placental methylome The placental DNA methylation landscape is unique, with widespread partially methylated domains (PMDs). The placental “methylome” is conserved across …

Excited to share our most recent work in Cell Stem Cell, led by @georgiaplea.bsky.social, characterising determinants of DNA methylation patterning in human trophoblast stem cells! A great collaboration with @vpglab.bsky.social.
tinyurl.com/93mchcd2

@loke-ctr.bsky.social @cam-repro.bsky.social

08.01.2025 16:21 — 👍 54    🔁 18    💬 6    📌 4

The GPI-anchor biosynthesis pathway is critical for syncytiotrophoblast differentiation and placental development - Cellular and Molecular Life Sciences The glycosylphosphatidylinositol (GPI) biosynthetic pathway in the endoplasmic reticulum (ER) is crucial for generating GPI-anchored proteins (GPI-APs), which are translocated to the cell surface and ...

link.springer.com/article/10.1...

21.12.2024 12:26 — 👍 1    🔁 0    💬 0    📌 0