Over the last year, we added almost 30k samples to our repository and now have over 140 datasets. This is Naveensri Saravanan giving our 2025 update. Thank you for visiting us at #ASHG2025!

Hi-C and Capture Hi-C experiments create massive amounts of raw data that's hard to navigate. In this poster from #ASHG2025. Pavel Kuksa introduces CHARMER, a unified pipeline for mapping and harmonizing data. #genomics #gwas

The Federated European Genome–Phenome Archive as a global network for sharing human genomics data - Nature Genetics In this era of rapidly expanding human genomics in research and healthcare, efficient data reuse is essential to maximize benefits for society. In response, the Federated European Genome–Phenome Archi...

Discover more about FEGA’s journey and the future plans for the resource in the recent FEGA landmark paper published in Nature Genetics 👇
www.nature.com/articles/s41...

📣📣Genomic data sharing: you don’t know what you’ve got (till it’s gone) www.nature.com/articles/s41...

A comment @natrevgenet.bsky.social from @katholt.bsky.social and me

Jeffrey Cifello presenting a poster yesterday titled "A fine-mapped multiomic human brain xQTL atlas and online portal leveraging four cohorts and six molecular phenotypes from the Alzheimer’s Disease Sequencing Project" #ASHG25

Check out the poster in full!

On Wednesday, Shaney Chuang from the WangLab presented a poster on the talk #ASHG25

Dr. Fanny Leung from the WangLab giving a Lightning Talk titled "Integrating 76,000 #GWAS from ADSP Release R (R^) to Accelerate Alzheimer’s Disease Genetics Research" #ASHG25

Hopefully you didn't miss it!

Our own Emily Greenfest-Allen presented a talk titled "Genomic Frontiers in Alzheimer's Research: A Primer on the Alzheimer's Disease Sequencing Project and its AI/ML Opportunities" #ASHG25

On Tuesday, Dr. Li-San Wang presented at AWS Community Day in a talk titled "Scaling discovery in Alzheimer’s genetics with NIAGADS on AWS" #ASHG #genomics

NEW DATASET!

Four large scale pQTL and mQTL atlases in plasma from European and African ancestral groups. #genomics #alzresearch
dss.niagads.org/datasets/ng...

New Dataset summary available for use!

Combines two releases with a sample of 35,274 clinical and autopsy-documented Alzheimer’s disease cases and 59,163 controls. #genomics #alzresearch

dss.niagads.org/datasets/ng...

Sodium benzoate treatment decreased amyloid beta peptides and improved cognitive function among patients with Alzheimer’s disease: secondary analysis of a randomized clinical trial - Translational Psychiatry Translational Psychiatry - Sodium benzoate treatment decreased amyloid beta peptides and improved cognitive function among patients with Alzheimer’s disease: secondary analysis of a...

🧠 Sodium benzoate and Alzheimer’s

A new study found that higher doses of sodium benzoate, a common food preservative, lowered amyloid beta proteins and improved memory in people with mild Alzheimer’s.

🔗 www.nature.com/articles/s41...

#SciComm #Alzheimers 🧪

As a member of @model-ad.bsky.social it pains me to acknowledge that @niagads.bsky.social won the #AAIC25 swag battle. Well played!

NIAGADS Office Hours are returning with a new format!

Launching this month are 1:1 Help Hours for those looking to connect with our team over specific topics. Sign Up Below!
#genomics #GWAS

www.niagads.org/help-hours/

New alz #dataset includes summary stats for a GWAS meta-analysis of 11 neuropathology endophenotypes

Included are neuritic plaques, tau neurofibrillary tangles, amyloid-beta plaques, Lewy body deposits, and hippocampal sclerosis, etc.

dss.niagads.org/datasets/ng...

#alzheimersresearch #datascience #bioinformatics #fairdata #adrc #openscience #nacc #nia | Sarah Biber, PhD 🚀 Just Launched: NACC’s Multimodal Query Tool (MQT v1) We’re thrilled to debut the initial release of the initial Multimodal Query Tool prototype (MQT v1)—now live and freely available to the global research community via the NACC Data Front Door

Just launched from NACC Data
The Multimodal Query Tool prototype lets you
🔎 Search, visualize, and access data on ADRC participants 
📊 Evaluate data fitness for specific research questions 
📈 Monitor sample size and key characteristics in real time 
www.linkedin.com/posts/sara...

Limited data hurts our ability to detect risk variants in non-white groups in #GWAS. We constructed a multi-ancestry collection of datasets in ADGC to test for population-specific late-onset #Alz susceptibility loci

New dataset in DSS!
dss.niagads.org/datasets/ng...

How can NIAGADS be useful for #AIML applications?

A new paper in the Journal of Alzheimer's and Dementia highlights how LLMs may pave the way for innovative therapeutic solutions and interdisciplinary collaboration

journals.sagepub.com/doi/10...

Emily Greenfest-Allen, PhD, will present at research session: Gene Discovery and Drug Development For Alzheimer’s Disease

Check out her talk! Genomic Frontiers in Alz Research: A Primer on the Alzheimer's Disease Sequencing Project and AI/ML Opportunities, 2:36 PM in Hall ABC

Stop by booth 609 to talk to the NIAGADS team! Subject matter experts for the following topics will be available at the times below #AAIC2025

Join Slido: Enter #code to vote and ask questions Participate in a live poll, quiz or Q&A. No login required.

There’s still time to participate in our booth activity at #AAIC2025 Tell us what you’d like to see in a conference session hosted by NIAGADS using the link below:

wall.sli.do/event/8Zs5EYd98...

Stop by booth 609 to talk to the NIAGADS team! Subject matter experts for the following topics will be available at the times below #AAIC2025
dss.niagads.org/visit-niaga...

Congrats to Kurt Farrell and co-authors for winning 2024 paper of the year from ISTAART!

Co-author, Adam Naj attended the ISTAART PIA Day on Saturday to receive the certificate

GWAS summary statistics for this pape can be accessed on DSS #AAIC2025

GenomeWeb NIH Funding Survey Take this survey powered by surveymonkey.com. Create your own surveys for free.

Are you a principal investigator at a research organization in the US? Please participate in GenomeWeb's five-minute survey to assess the impact of the current NIH funding environment on life science research!

The survey is here: www.surveymonkey.com/r/GWNIHsurvey

NIAGADS: A Comprehensive National Data Repository for Alzheimer's Disease and Related Dementia Genetics and Genomics Research - PubMed https://pubmed.ncbi.nlm.nih.gov/39417134/

NIAGADS: A Comprehensive National Data Repository for Alzheimer’s Disease and Related Dementia Genetics and Genomics Research NIAGADS is the National Institute on Aging (NIA) designated national data repository for human genetics research on Alzheimer’s Disease and related dementia (ADRD). NIAGADS maintains a high-quality…

In case you didn't hear, a preprint was released reintroducing NIAGADS! We host extensive genetic data and support global collaborations to advance research and treatment

Also, we have a bluesky now! 😁
Check out the preprint
#genesky