Dame lab at Leiden University

Talk slots full but we can take late breaking poster abstracts until August 7th. Hope to see you in York to hear about your chromosome story 🧬🦠🧫

www.eventsforce.net/biochemsoc/f...

@vslioy.bsky.social @damelab.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social @biophychrom.bsky.social

Great to see it published, Daniela!

Poster advertising the Biology and Physics of Prokaryotic Chromosomes conference that will be held in York, 16-19 September 2025.

Just few days left to register for this chromosome biology fête! 🧬🧬🧬

⏳📆 16 July

www.eventsforce.net/biochemsoc/f...

@vslioy.bsky.social @damelab.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social @biophychrom.bsky.social

The role of nucleoid-associated proteins in mediating responses to environmental changes Bacteria face diverse environmental challenges, such as changes in temperature, pH, and osmolarity, and exposure to antibiotics, which necessitate ada…

I am pleased to share our new review on the role of bacterial nucleoid-aasociated proteins in mediating responses to changes in environment. Important: some NAPs can directly ‘sense’ physico-chemical changes. www.sciencedirect.com/science/arti... @pingzhuangge.bsky.social

York calling! 📣 🧬🧬🧬

Join us at www.biochemistry.org/events-and-t...

⏳⏰ Early bird deadline approaching soon, 16 July! Do not miss out! Half of the talks selected from abstracts.
@damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social @biophychrom.bsky.social

Histone-mediated chromatin organization in prokaryotes and viruses Histones are fundamental chromatin-organizing proteins in eukaryotes and archaea, where they assemble into (hyper)nucleosomes that wrap DNA. Recent studies have expanded the known repertoire of histon...

A must-read for histone afficionados: our new review on 'Histone-mediated chromatin organization in prokaryotes and viruses' www.cell.com/trends/bioch... @samuelschwab.bsky.social @vikramalva.bsky.social

Flyer advertising The Biology and Physics of Prokaryotic Chromosome conference that will be held in York, 16-19 September 2025.

Chromosome Enthusiasts, join us at The Biology & Physics of Prokaryotic Chromosomes 🧬! Friendly community, fantastic speakers line-up, grant writing session for ECRs. Early-bird deadline approaching soon.
@damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biophychrom.bsky.social

We’ve uncovered Asgard chromatin structures formed by a Hodarchaeal histone : closed hypernucleosome conserved in archaea and an open form resembling the H3-H4 eukaryotic octasome. Fantastic work by @harshranawat.bsky.social!
www.biorxiv.org/content/10.1...
#Chromatin #Asgard #Archaea #cryoEM

So very nice to see the pre-print online - it’s a beautiful story! We’re happy to have been involved.

Join us in York for the Biology & Physics of Prokaryotic Chromosomes! 🧬 #Microsky #Archaeasky

www.biochemistry.org/events-and-t...
@biochemsoc.bsky.social
@damelab.bsky.social @graingerlab.bsky.social @vslioy.bsky.social

New vacancy in my team!

PhD student position on microbial genome evolution, focusing on the evolutionary principles underlying bacterial genome architecture.

Please repost and share with talented MSc students in #evobio, bioinformatics or related :)

www.uu.nl/en/organisat...

#MEvoSky #MicroSky

It’s great to see this online. We are very glad to have been able to contribute to this work on yet an other very interesting type of bacterial histone.

A snapshot of the HLp tetramer (purple) wrapping ~60 bp of DNA (green).

Excited to share our new preprint on HLp—a bacterial histone from Leptospira perolatii that forms stable tetramers and wraps ~60 bp of DNA: "DNA Wrapping by a Tetrameric Bacterial Histone" www.biorxiv.org/content/10.1...

@mpi-bio-fml.bsky.social

Prokaryotic Chromosome Organization: part 2: Molecular Microbiology: Vol 123, No 3 Molecular Microbiology is a broad-scope microbiology journal for basic and translational research that contributes to understanding molecular principles in microbes.

Chromatin aficionados take note:
Second of two special issues on Prokaryotic Chromosome Organization now published!
(6 review/perspective articles and 2 research articles)
Guest edited by @damelab.bsky.social
#MicroSky #Chromatin

onlinelibrary.wiley.com/toc/13652958...

Postdoc Comparative genomics and genome architecture in early-diverging fungi and their protist relatives (3-year position)

Exciting news! I'm looking for a computational biologist to join my lab at Wageningen University & Research! It's a 3-year postdoc position on Holomycota genome architecture and evolution. Spread the word! www.wur.nl/en/vacancy/p...

Can I tempt some young minds to consider Old York for a PhD?

Some days left to apply.
Open to applicants WORLDWIDE 🌎.

Returning from a great visit to the Dodonova lab at EMBL to discuss archaeal histones and hypernucleosomes. Nice also to see a tribute to the hypernucleosome on EMBL premises !#Archaeasky

Prokaryotic Chromosome Organization: part 1: Molecular Microbiology: Vol 123, No 2 Molecular Microbiology is a broad-scope microbiology journal for basic and translational research that contributes to understanding molecular principles in microbes.

First of two special issues on Prokaryotic Chromosome Organization now published! Guest edited by @damelab.bsky.social

#MicroSky #Chromatin

onlinelibrary.wiley.com/toc/13652958...

Really great to see the Reviews, Perspectives and Research articles of these special issues published. Many thanks to all contributors, and for the support of the field for the BioPhyChrom meeting series. Registration is open for the upcoming incarnation of the meeting in York, UK, Sept. 16-19 2025.

Future Directions of the Prokaryotic Chromosome Field In September 2023, the Biology and Physics of Prokaryotic Chromosomes meeting ran at the Lorentz Center in Leiden, The Netherlands. As part of the workshop, those in attendance developed a series of ....

In @molecularmicro.bsky.social: two special issues on Prokaryotic Chromosome Organization. Many excellent contributions, including a vision article: 'Future directions of the Prokaryotic Chromosome Field', outcome of BioPhyChrom 2023 @biophychrom.bsky.social onlinelibrary.wiley.com/doi/10.1111/...

Celebrating the 450th birthday of Leiden University today. I am visiting elementary school De Lichtwijzer for ‘Meet the professor’. Nice!

Registration is now open for The Biology and Physics of Prokaryotic Chromosomes meeting in York, UK. 16-19 September 2025

Still time to apply for this PhD project with the awesome 🙌 @steve-quinn-lab.bsky.social, @georgerheath.bsky.social and me.

By the way, York is a beautiful 🤩 historic city!
Please repost, grazie 😊 🌷.

We will be soon advertising for a new postdoc position - contact us if you are interested (bioinformatics/ML/biophysics of nucleosome positioning in cancer)

For information on upcoming BioPhyChrom conferences and any other information we deem relevant for the community please start following @biophychrom.bsky.social

Soon possible to register for BioPhyChrom VII in September 2025 www.biochemistry.org/events-and-t...

We are excited to announce the first Salamanca Biophysics Summer Course organized by Carlos Bustamante and Eva Nogales. See the flyer below and consider applying!

It was very nice to work together with you and others in this multi-lab effort.

Welcome to BlueSky, Ilaria!

Circular oligomeric particles formed by Ros/MucR family members mediate DNA organization in α-proteobacteria Abstract. The transcriptional regulator MucR from Brucella species controls the expression of many genes, including those involved in virulence, by binding

Very pleased to have contributed to this multi-lab study into the structure and function of Ros/MucR family proteins. Strikingly, these proteins form circular oligomers and function as H-NS-like proteins. The study was led by Ilaria Baglivo, University of Campania.
academic.oup.com/nar/advance-...

A great day for our lab and for prokaryotic chromatin at the Dutch Chromatin meeting: Pingzhuang won the 1st prize for his poster and Samuel gave an excellent talk on prokaryotic histone diversity!