The Buck Institute for Research on Aging

From the Buck Institute: The Secret to a Longer Life? It’s Not in a Bottle. It’s in a Conversation The Buck Institute highlights the importance of meaningful connections for enhancing our healthspan and well-being.

Don’t miss our CEO Eric Verdin’s monthly column in Marin Magazine! The latest is all about how your social life can boost your longevity! marinmagazine.com/health/healt...

Seats are selling fast! Register for our upcoming seminar on Wed, Aug 6. Find out how an array of technologies and AI, capturing an individuals’ data, can explain our health and longevity. www.buckinstitute.org/events/lblse...

A pleasure to be interviewed by David Rubenstein for his new Bloomberg TV show on longevity. We’ll let you know when we have an air date!

Seats are selling fast! Register for our upcoming seminar on Wed, Aug 6. Find out how an array of technologies and AI, capturing an individuals’ data, can explain our health and longevity.
www.buckinstitute.org/events/lblse...

Our first seminar of new season of our Live Better Longer Community Seminar series today! Great talk by Dr Brianna Stubbs, the Co-Dir of our Clinical Research Unit at Buck. She’s expert in exogenous ketone metabolism and its implications for performance, resilience & healthspan.

Congratulations to our CEO, Eric Verdin, Dobri Kiprov and Circulate Health for receiving the award for the most significant therapeutic advance in the science of aging at the recent #LongevityDocs meeting in Cannes.

Neurons burn sugar differently. The discovery could save the brain. In addition to a new approach in Alzheimer’s research, study from Buck Institute could explain why GLP-1 drugs show promise against dementia.

Neurons burn #sugar differently. The discovery from the Kapahi lab could save the brain. Study in Nature Metabolism
provides new approach in #Alzheimers research and could explain why #GLP1 drugs show promise against #dementia buckinstitute.org/news/neurons...
@pkapahi.bsky.social

Neurons burn sugar differently. The discovery could save the brain. In addition to a new approach in Alzheimer’s research, study from Buck Institute could explain why GLP-1 drugs show promise against dementia.

Neurons burn #sugar differently. The discovery from the Kapahi lab could save the brain. Study in Nature Metabolism provides new approach in #Alzheimers research and could explain why #GLP1 drugs show promise against #dementia www.buckinstitute.org/news/neurons...
@kapahi_pankaj @KapahiLab

Our CEO, Eric Verdin was on a panel at the 28th annual @milkeninstitute Global Conference. The Panel focused on “The Roadmap to Longevity,“ addressing the latest scientific breakthroughs and discussed what’s on the horizon in the quest to live to 100 in good health. #MIGlobal

Marin Magazine July 2025 Thought-provoking stories, profiles of Marin personalities, journeys to destinations near and far — plus the best places to dine, shop, play, and enjoy Marin County and beyond — Marin Magazine is the

Check out the July edition of @MarinMagazine! Our CEO, Eric Verdin's first column "How to Live Better Longer" is on Page 22 and go to Page 70 to use the QR code to register for our upcoming seminar next week! issuu.com/270media/doc...

World’s leading aging researchers have united to accelerate breakthroughs in longevity. Members of Academy for Health and Lifespan Research (including Buck’s Eric Verdin and Gordon Lithgow) describe efforts to accelerate promise of #geroscience @NatureAging www.nature.com/articles/s43...

Drink up! (Water please) Dehydration is a major risk factor for bad things in older adults – including death

It’s summer. #Drink up (water please)! Our #thirst mechanisms decline with age. #Dehydration can be deadly. A project at the Buck is focused on intervening where those processes begin – in the brain. Down a glass of #water while you read our new blog post. www.buckinstitute.org/blog/drink-u...

Live Better Longer Community Seminar Series July 2, 2025 @ 11:00 am - 12:00 pm - The Buck Institute is hosting in-person (with zoom option) monthly conversations with geroscience experts about how people can live longer, healthier lives. Speake...

Get the scoop on our clinical trials at our July 2 seminar with Dr. Brianna Stubbs. She’ll talk about “intrinsic capacity.” It’s a new way of looking at aging and something you should discuss with your doctor. She’ll talk about ketogenic diets too! www.buckinstitute.org/events/lblse...

The same technology that enables targeted immunotherapy for cancer could be used to tackle Alzheimer's Proof-of-concept study shows CAR cells can detect both tau tangles and various forms of amyloid plaques

The technology that enables targeted immunotherapy for cancer could be used to tackle #Alzheimers. Proof-of-concept study shows CAR cells can detect both tau tangles and various forms of amyloid plaques. Study stems from Transformational Research Award.
www.buckinstitute.org/news/the-sam...

Our Live Better Longer Community Seminar Series is back!! Our first seminar of this season on July 2nd will be incredible! We'll be sharing what we’re learning in our clinical trials that can help you live better longer. Register today! www.buckinstitute.org/events/lblse...

Sleep regularly. Move your body. Stay fit. Recover well. Delighted to collaborate with @WHOOP on WHOOP Healthspan. Check out their White Paper. assets.ctfassets.net/rbzqg6pelgqa...

A New Blood-Based Epigenetic Clock for Aging Focuses on Intrinsic Capacity New tool provides a path for a scalable, cost-effective way to assess functional decline and could help end the argument over whether aging should be categorized as a disease.

New blood-based clock for #aging focuses on intrinsic capacity. Study in @nataging.nature.com provides path to scalable, cost-effective way to track functional decline and could help end argument over whether aging should be categorized as a disease. www.buckinstitute.org/news/a-new-b...

Docent-led Tours at the Buck Every Tuesdays and Thursdays at 11am. Reservations are required.

Hey! Come visit us at the Buck! Take a free docent-led tour of our beautiful I.M Pei designed facilities and hear about the breakthrough science happening at the Buck. The views are amazing! and the science is even better! Register for a tour here: www.buckinstitute.org/news/docent-...

Clinical Trial and Multi-omics Analysis Demonstrates the Impact of Therapeutic Plasma Exchange on Biological Age Study in Aging Cell shows that therapeutic plasma exchange combined with intravenous immunoglobulin reduced biological age on average by 2.6 years, as measured by multi-omics biomarkers

Read more about the study in Aging Cell that shows therapeutic #plasma exchange combined with intravenous immunoglobulin reduced biological age on average by 2.6 years. Great to team up with Circulate Health on this.
www.buckinstitute.org/news/clinica...

Could Plasma Exchange Therapy Actually Help You Live Longer?

Our f​irst-of-its-kind study published today in Aging Cell shows #plasma exchange may reduce biological age. Great to team up with Circulate Health . Lots of work left to do but really exciting potential here!
www.nytimes.com/2025/05/28/w...

The Buck’s Impact Circle supports a project aimed at taming age-related muscle loss via the gut Sarcopenia, age-related loss of muscle mass and strength, increases the risk of falls, fractures and overall functional decline. There are no FDA-approved treatments for the condition. The Buck’s Impa...

The Impact Circle, our popular donor group, has made their choice. This year they will support a project aimed at taming age-related muscle loss via the gut. Congrats to postdoc Taylor Valentino an ultramarathon runner who will lead the effort. www.buckinstitute.org/news/the-buc...

Age-associated nicotinamide adenine dinucleotide decline drives CAR-T cell failure - Nature Cancer Vannini and colleagues report that an age-associated decline in nicotinamide adenine dinucleotide levels is associated with mitochondrial dysfunction and reduced antitumor efficacy of chimeric antigen...

Age-related decline in #NAD levels impairs metabolism reducing the effectiveness of CAR-T cell cancer treatments. Study in @natcancer.nature.com shows boosting NAD in preclinical models revived antitumor properties in immune cells www.nature.com/articles/s43...

Raising Up the Next Generation of Aging Researchers Community Learning & Engagement in Aging Research

Register for seminar on May 21! Be part of something transformative! Raising Up the Next Generation of Aging Researchers is more than just a seminar, it's a dynamic fundraising event designed to spotlight and support the rising stars of aging research. www.buckinstitute.org/events/next-...

XPRIZE Healthspan names top 100 teams advancing healthy aging Global competition enters clinical phase as selected teams work to restore immune, cognitive and muscular function in older adults

Thrilled that our Buck team, with partners at Univ of Toulouse, is a semifinalist for the $101M XPRIZE Healthspan. Goal is to restore muscle, cognition and immune function by at least 10 years in people 50+ years old. longevity.technology/news/xprize-... @xprize #xprizehealthspan

Buck Institute Team is Named Semifinalist of XPrizre Healthspan $101 Million Global Competition Aims to Revolutionize How We Approach Aging

Yahoo! A Buck team (along with collaborators at Univ. of Toulouse) have made it into semifinals of $101M XPRIZE Healthspan! Our project is the most robust non-drug intervention to date designed to improve Intrinsic Capacity. www.buckinstitute.org/news/buck-in... @xprize.org #XPRIZEHealthspan

Replacement as the Future of Healthy Aging A new perspective in Nature Aging posits a new unified framework of replacement for aging. It is a significant contribution to the field of aging with a stellar group of coauthors.

A new perspective in @nataging.nature.com posits a new unified framework of replacement for aging. It is a significant contribution to the field of aging with a stellar group of coauthors. Our latest blog post gives you highlights. www.buckinstitute.org/blog/replace...

Come on a [free] tour of Buck! Not only are the buildings really beautiful but what we do inside the buildings is super interesting and inspiring! You’ll learn something and have fun! Buckinstitute.org/visit-us

Team Buck! at Reproductive Aging Conference 2025 at Hayes Mansion in San Jose.
1st photo left to right: Dr. Allison Kochersberger, Dr. Francesca Duncan, Dr. Malene Hansen, Dr. Jennifer Garrison, Dr. Olga Bielska, Dr. Parminder Singh, Katelyn Adam, Dr. Deena Emera, Dr. Bikem Soygur Kaya

Last Friday we hosted FRS speaker, Dr. Frank Longo from Stanford. He gave a fascinating talk on preclinical and clinical research on Alzheimer’s disease.

Reproductive Aging Conference 2025 has been kicked off by organizers Jennifer Garrison from Buck, Yousin Suh from Columbia University, and Francesca Duncan from Northwestern University, in San Jose, CA. Jennifer gave inspiring introductory notes and now on to several days of great research!