Barun Pradhan

Had great fun hearing about it as you were developing it. Great to see this work out! Congrats Alex, Dan and the team!

13.04.2025 12:07 — 👍 1    🔁 0    💬 0    📌 0

Error-corrected flow-based sequencing at whole-genome scale and its application to circulating cell-free DNA profiling Nature Methods - This work integrates duplex sequencing with cost-effective Ultima sequencing to enhance the accuracy of whole-genome circulating cell-free DNA profiling.

What happens when sequencing costs go ⏬ ?
Imagination and new opportunities go ⏫
@landau.bsky.social

Let's look at what you can do when you perform deep WGS on cfDNA for cancer detection. Our recent work with the
@UltimaGenomics
platform 🧵👇
Lets goooo!!
rdcu.be/ehkUb

11.04.2025 15:53 — 👍 10    🔁 7    💬 3    📌 2

Postdoc: Molecular Biology/Genetics/Developmental Biology/Evolution/Computational Biology

I'm looking for a postdoc to join my fantastic team at the NIH in Bethesda, MD. Great resources. Competitive salary. www.training.nih.gov/jobs/pdf-mb-...

08.01.2025 19:06 — 👍 6    🔁 9    💬 0    📌 1

Congratulations Ivan, Jackie and the team. Excited to read this up!

05.01.2025 23:01 — 👍 0    🔁 0    💬 0    📌 0

Single-cell mapping of regulatory DNA:Protein interactions Gene expression is coordinated by a multitude of transcription factors (TFs), whose binding to the genome is directed through multiple interconnected epigenetic signals, including chromatin accessibil...

🧬 We’re excited to introduce D&D-seq, a single-cell technology that maps DNA:Protein interactions through molecular footprinting. Check it out here: biorxiv.org/content/10.1... #Genomics #Epigenetics

02.01.2025 21:10 — 👍 53    🔁 14    💬 3    📌 1

This is so cool!! Looking forward to this being available in NEB shelves. Kudos to the team!!

13.12.2024 06:39 — 👍 1    🔁 0    💬 0    📌 0

Regulation of human interferon signaling by transposon exonization Transposable element exonization can yield functional protein isoforms as seen for primate-specific IFNAR2.

I’m excited to share our latest study led by @giuliapasquesi.bsky.social out today in @cellpress.bsky.social , uncovering a new way transposons have been repurposed for human interferon signaling! Read on for a thread on cryptic splice variants, decoy receptors, and viruses (1/N) 👇🧵 #TESky 🧪

12.12.2024 18:56 — 👍 154    🔁 74    💬 12    📌 7

🧬 🧠 Excited to see it printed! We bring key insights on the epigenetic regulation of SVAs, including SVA-XDP: a polymorphic SVA driving a rare neurodegenerative disorder

@jakobssonlab.bsky.social @vivienhorvath.bsky.social
#TEworldwide #Transposons #XDP #NSMB
+ the volume has the cutest cover 🦔

27.11.2024 16:58 — 👍 14    🔁 5    💬 0    📌 0

Excited to share this new publication where we did a comprehensive analysis of standard (short-read) 10x single-cell RNAseq data to show that the locus-specific expression of LINE-1s can be detected based on the transcriptional readthrough. rdcu.be/dzrSl

23.02.2024 15:58 — 👍 3    🔁 1    💬 0    📌 0