Alexandre Bodin

Great data presented in this study of >23k patients with AF from 2007-2021 regarding AAD use after ablation (46% after 1st), redos after index ablation (16%), RR of repeat ablation with various risk fx's (lsps AF vs pAF 2.26, AAD use 1.42, etc). Worth a read for #EPeeps

www.jacc.org/doi/10.1016/...

Artificial intelligence for individualized treatment of persistent atrial fibrillation: a randomized controlled trial - Nature Medicine In a randomized controlled trial in individuals with persistent atrial fibrillation, an individualized ablation procedure, in which areas with abnormal electrophysiological characteristics—as detected...

TAILORED-AF just published!

#cardiosky

Cardiac venous system mapping for ventricular arrhythmia localization The coronary venous system offers a route for mapping and ablation of ventricular arrhythmias with suspected epicardial or intramural origins. Coronary venous mapping helps the operator to select the ...

Cardiac venous system mapping for ventricular arrhythmia localization - Heart Rhythm O2 www.heartrhythmopen.com/article/S266...
Absolute must read for trainees and all those interested in PVC ablation #CardioSky #EPeeps

🫀 A new study validates the SPICT (Supportive and Palliative Care Indicator Tool), which identifies hospitalized HF pts at high mortality risk.

Key Findings:
✔ SPICT-JP +: >3x ⬆️ mort risk
✔ Aids in advance-care planning for EoL decisions.

🔗https://bit.ly/4g0Lou8

New atlas maps regional left ventricular scars in cardiomyopathies - a guide to diagnose causes beyond just ischemic heart disease. Patterns like septal fibrosis in laminopathies or apical scarring in Chagas can point to specific etiologies. #MedEd #MedSky #CardioSky https://buff.ly/3Em4C0g

Learn more about antiarrhythmic drugs during pregnancy.

Looking for more info? Check out the state of the art review on pregnancy and arrhythmias: www.jacc.org/doi/10.1016/...

#HeartMonth

U.S. Mortality trends in the young, ages 25-44 years
jamanetwork.com/journals/jam...
Drug overdoses are the leading cause of excess mortality. There were substantial numbers of Covid fatalities in this age group during the peak pandemic

Figure 1. Atrial Fibrillation Stages and the Evolution of Atrial Pathology

Atrial fibrillation (AF) is associated with increased rates of stroke, heart failure, and mortality.

This narrative review examines the epidemiology, pathophysiology, diagnosis, and treatment of AF.

➡️ ja.ma/3PP0yrY

#MedSky

Welcome immigrants from X interested in science to the friendlier skies of @bsky.app, as documented by a new @nature.com survey (but you already knew that 😉)
"Bluesky is much better for science. There is much less toxicity, misinformation, and distractions."
www.nature.com/articles/d41...

Effect of Sequential, Colocalized Radiofrequency and Pulsed Field Ablation on Cardiac Lesion Size and Histology
www.ahajournals.org/doi/10.1161/...

The cumulative incidence of the primary end point event of major or clinically relevant nonmajor bleeding. The inset shows the same data on an expanded y axis.

In patients with atrial fibrillation and moderate-to-high risk of stroke, abelacimab, a monoclonal antibody that inhibits activation of factor XI, led to fewer bleeding events than rivaroxaban. Read the full AZALEA–TIMI 71 trial results: nej.md/3PJcknN

#MedSky #Cardiology

Image showing 3 panels. The first panel shows a ECG tracing from a patient during an episode of ventricular fibrillation. The second panel shows a grayscale image of cells with individual cells highlighted and corresponding activity traces from calcium imaging. The third panel details the model used for computational modeling to identify molecular targets for IVF.

We outline a new paradigm for identifying functional and molecular targets #arrhythmia suppression in patients with idiopathic ventricular arrhythmia www.jacc.org/doi/10.1016/...

Mavacamten: Real-World Experience From 22 Months of the Risk Evaluation and Mitigation Strategy (REMS) Program | Circulation: Heart Failure BACKGROUND: Mavacamten is the only cardiac myosin inhibitor approved by the U.S. Food and Drug Administration for the treatment of patients with symptomatic New York Heart Association class II–III obs...

Mavacamten: Real-World Experience From 22 Months of the Risk Evaluation and Mitigation Strategy (REMS) Program
www.ahajournals.org/doi/10.1161/...

Trust in scientists and their role in society across 68 countries - Nature Human Behaviour What is the state of trust in scientists around the world? To answer this question, the authors surveyed 71,922 respondents in 68 countries and found that trust in scientists is moderately high.

"Most people trust scientists and agree that scientists should engage more in society and policymaking"
From a 68-country assessment. Open-access
www.nature.com/articles/s41...

🔥 New in #JACC: #Wildfires and extreme events are increasing cardiovascular risks. Full read: www.jacc.org/doi/10.1016/...

Experts urge cardiologists to lead efforts in anticipation, mitigation and adaptation. #CardioSky #MedSky @accintouch.bsky.social @hmkyale.bsky.social @kaichenyale.bsky.social

True but how could you randomize such trials?

No worries…. It is not pointless when you are french !

Atrial fibrillation recurrence in patients with transthyretin cardiac amyloidosis undergoing pulmonary veins isolation - Journal of Interventional Cardiac Electrophysiology Journal of Interventional Cardiac Electrophysiology -

PVI+ as first line in ATTR patients or no ablation in such patients?

Ablation Strategies for Repeat Procedures in Atrial Fibrillation Recurrences Despite Durable Pulmonary Vein Isolation: The Prospective Randomized ASTRO AF Multicenter Trial | Circulation BACKGROUND: Ablation strategies for patients with symptomatic atrial fibrillation and isolated pulmonary veins vary and their effects on arrhythmia recurrence remain unclear. A prospective randomized ...

ASTRO-AF: no superiority of LAA isolation by cryo over low voltage area ablation (55 vs. 51% of récurrence at 1 year)

Link:
www.ahajournals.org/doi/10.1161/...

Electrical isolation of the left atrial appendage in East Asian patients with atrial fibrillation The left atrial appendage (LAA) is a source of non–pulmonary vein triggers in patients with atrial fibrillation (AF). Electrical isolation of the LAA (EILAA) improves rhythm outcome with an inherent risk of embolism unless lifelong anticoagulation is continued. However, evidence of the efficacy and safety of EILAA in the East Asian population remains lacking.

'The left atrial appendage (LAA) is a source of non–pulmonary vein triggers in patients with atrial fibrillation (AF). Electrical isolation of the LAA (EILAA) improves rhythm outcome with an inherent risk of embolism unless anticoagulation'
#Epeeps #cardiosky
www.heartrhythmopen.com/article/S266...

Urinary tartaric acid as a biomarker of wine consumption and cardiovascular risk: the PREDIMED trial AbstractBackground and Aims. Moderate wine consumption has been associated with lower cardiovascular disease (CVD) risk in older populations. However, wine

Light to moderate consumption of wine is associated with a lower cardiovascular disease risk.

Our latest in @jaccjournals.bsky.social!

2024 ACC Expert Consensus Decision Pathway on Practical Approaches for #Arrhythmia Monitoring After #Stroke

Grateful for this opportunity to collab with #Neurosky #Cardiosky & #EPeeps for better care of our patients!

🔗 www.jacc.org/doi/10.1016/...

Differential and synergistic effects of right and left atrial ganglionated plexi ablation in patients undergoing cardioneuroablation: results from the ELEGANCE multicenter study - Journal of Intervent... Background Cardioneuroablation (CNA) treats reflex syncope by ablating ganglionated plexi (GPs) either confined to the right (RA) or left atrium (LA), or accessible from both. We assessed whether GP a...

link.springer.com/article/10.1...

Small but interesting study showing LA 1st CNA had superior acute affects to RA 1st CNA in biatrial CNA. #EPeeps #CardioSky #MedSky

www.ahajournals.org/doi/10.1161/...

Unfortunately i don’t think CircEP is on #CardioSky yet but an interesting paper looking at PFA or PFA+RFA for SVT. #EPeeps

Left bundle branch pacing vs ventricular septal pacing for cardiac resynchronization therapy - PubMed In patients undergoing CRT, LVSP had comparable CRT outcomes compared with LBBP.

LVSP is enough!

#Epeeps #Cardiosky

All the major medical journals are joining BlueSky. Every day more docs are as well. Would love to see more of our interventional cardiology colleagues here. #MedSky #CardioSky

Impact of dispersive patch electrode positioning on safety and efficacy of radiofrequency catheter ablation Abstract. Safe and efficient radiofrequency catheter ablation depends significantly on the proper placement of dispersive patch electrodes (DPEs), on the s

academic.oup.com/europace/art...

RV and biV pacing when no VT are induced?

#cardiosky #Epeeps

In 1932, Hamilton and Rompf published one of the most entertaining physiology papers I have ever read. They determined that the change of the external volume of the heart during the cardiac cycle was minimal. journals.physiology.org/doi/pdf/10.1...

Pleased to share our article on sinus node function & the role of sinoatrial remodelling in the genesis of the atrial flutter substrate, a 3D mapping & computational modelling study published in Heart Rhythm

doi.org/10.1016/j.hr...

1/3

#CardioSky #EPeeps

Aggressive Risk Factor Reduction Study for Atrial Fibrillation and Implications for the Outcome of Ablation: The ARREST-AF Cohort Study The long-term outcome of atrial fibrillation (AF) ablation demonstrates attrition. This outcome may be due to failure to attenuate the progressive sub…

Risk factor reduction is mandatory!

#Cardiosky #EPeeps

www.sciencedirect.com/science/arti...