Marie Delaby

How bacteria grow: evolutionary differences point to new ways to combat infection Discovering unsuspected flexibility in bacterial elongation, UdeM microbiologists rethink approach to fighting resistance to antibiotics.

#MICROBIOLOGY Scientists at @brunlabcaulo.bsky.social find "new points of fragility" in how bacteria cell walls expand, and this "could be exploited to develop new #antibiotics.” @mariedelaby.bsky.social ‪@natcomms.nature.com nouvelles.umontreal.ca/en/article/2...

Excited to share that I have been appointed F.R.S.-FNRS Research Associate to launch my independent research group at the University of Namur!
We will study the diversity, regulation & environmental control of bacterial cell elongation.
More soon- new projects, collaborations & opportunities ahead!

Exciting news!
My work with Liu Yang in the @brunlabcaulo.bsky.social, “Phenotypic plasticity in cell elongation among closely related bacterial species”, has been selected as an Editors’ Highlight in @natcomms.nature.com under Microbiology and infectious diseases!

Check it out here:

Phenotypic plasticity in cell elongation among closely related bacterial species - Nature Communications Multiple types of cell elongation have been described in bacteria, but little is known about how these strategies vary across species. Here, the authors use fluorescent D-amino acids to track the spat...

Excited to share that my postdoc work with Liu Yang, from @brunlabcaulo.bsky.social lab, is now out in @natcomms.nature.com !
How does your favourite bug grow? Elongation modes vary even between close relatives. We tracked PG insertion and uncovered surprising diversity within the Caulobacteraceae.

Please repost: Postdoc position in antibiotic discovery in a large multidisciplinary project combining high-throughput approaches, microscopy, AI, and hit-to-lead optimization at @umontreal.ca and @mila-quebec.bsky.social. Apply to ML.Antibiotics@gmail.com. See
lnkd.in/dVVk4N3s. #microsky

Cinq à Science (@cinqascience.bsky.social) On se retrouve autour d’un verre, on écoute une présentation, puis on échange de manière informelle. Lien: https://tinyurl.com/4t7nvz6y

Excited to share our Cinqascience.bsky.social and our sites.google.com/view/cinq-a-... where you’ll find all details about our activities in Montréal and Québec! A huge thank you to Mafar (from @svanteeffelen.bsky.social sky.social lab) for supporting our communication 💙 #CinqAScience #5AScience

How does your favorite species elongate? 🧵 "Phenotypic plasticity in bacterial elongation among closely related species" by @mariedelaby.bsky.social, Liu Yang et al https://buff.ly/48Kw96x. How do cells elongate, all over, poles, middle? Close species do it the same way right? Not quite! #Microsky

Assistant or Associate Professor in Bacteriology - Montréal, Quebec (CA) job with University of Montreal | 664282 Université de Montréal (UdeM) is looking for an Assistant or Associate full-time professor in the field of bacteriology.

#JobAlert for (Asst/Assoc) Professor in #bacteriology in our Department of Microbiology at the @UMontreal. Join our increasing group of bacteriologists including recent hires of
@brunlabcaulo.bsky.social, Frederique Le Roux and myself. jobs.sciencecareers.org/job/664282/a...

Check out our preprint for all the details on how these findings reshape our understanding of bacterial growth diversity! Huge thanks to my amazing collaborators for making this work possible! 5/5

Extending our analysis to other alphaproteobacteria like Rhodobacter capsulatus, we found that unidirectional midcell elongation isn’t limited to Caulobacteraceae and could be widespread within Alphaproteobacteria. 4/5

A key player? PBP2! In A. excentricus, PBP2 localizes at midcell during midcell elongation, contrasting its dispersed pattern in C. crescentus. This spatial organization appears crucial for directing growth patterns. 3/5

Using fluorescent D-amino acids (FDAA) to track peptidoglycan synthesis, we discovered that PG synthesis in Asticcacaulis excentricus starts at midcell and extends toward the new pole, while A. biprosthecum combines polar and midcell elongation- new growth modes among Caulobacteraceae relatives! 2/5

Phenotypic plasticity in bacterial elongation among closely related species Cell elongation is a fundamental component of the bacterial cell cycle and has been studied over many decades, in part owing to its mechanisms being a target of numerous antibiotic classes. While seve...

Excited to share my postdoctoral work from the Brun Lab @brunlabcaulo.bsky.social ! Together with Liu Yang, we uncovered surprising diversity in bacterial cell elongation within the Caulobacteraceae family—from unidirectional to polar elongation 🧵1/5: buff.ly/48Kw96x