Audrey Verhaeghe's Avatar

Audrey Verhaeghe

@audreyverhaeghe.bsky.social

PhD student in Xavier De Bolle's lab Working on envelope biosynthesis in Brucella abortus UNamur (Belgium)

32 Followers  |  61 Following  |  2 Posts  |  Joined: 31.01.2025  |  1.41

Latest posts by audreyverhaeghe.bsky.social on Bluesky

According to Alphafold3 predictions and homology modeling, the Mpc complex is composed of an octameric lipoprotein MpcA anchored at the outer membrane, interacting with a hexameric tunnel-like MpcD, itself associated with an inner membrane complex comprising MpcE and MpcF ATPase. Absence of the Mpc complex modifies the lipid composition of outer membrane vesicles, suggesting that Mpc could be involved in lipid transport between inner and outer membrane.

According to Alphafold3 predictions and homology modeling, the Mpc complex is composed of an octameric lipoprotein MpcA anchored at the outer membrane, interacting with a hexameric tunnel-like MpcD, itself associated with an inner membrane complex comprising MpcE and MpcF ATPase. Absence of the Mpc complex modifies the lipid composition of outer membrane vesicles, suggesting that Mpc could be involved in lipid transport between inner and outer membrane.

Great work by Adélie Lannoy on Brucella abortus, just published in The EMBO Journal www.embopress.org/doi/full/10..... Thanks to fantastic collaborators! An enigmatic, perhaps ancestral, protein complex predicted as a tunnel-like structure between membranes. Crucial for survival in macrophages

13.08.2025 13:26 — 👍 7    🔁 3    💬 0    📌 0
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I had the chance to present my data about VirB localisation in Brucella in an incredible place as Cape Town, South Africa 🌊🇿🇦 Thanks to the organizing committee of BMSV2025 for this opportunity and my colleagues for the amazing time we have together🪘#BMSV2025 @namurxa.bsky.social m

06.02.2025 15:59 — 👍 6    🔁 2    💬 0    📌 0
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I'm having a great time in South Africa at the BMSV2025 where I got the chance to present some of my data on DipM and cell divison in Brucella abortus 🧫
Very lucky to participate to such an interesting conference

#BMSV2025 @namurxa.bsky.social

05.02.2025 10:45 — 👍 7    🔁 1    💬 0    📌 0
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Great visit at the Cape Town botanic garden with a nice URBM delegation!... just before the BMSV conference

03.02.2025 11:25 — 👍 6    🔁 2    💬 0    📌 0

Congrats Adélie 🥳

31.01.2025 13:22 — 👍 0    🔁 0    💬 0    📌 0
Adélie with the external jury members present at her public defense

Adélie with the external jury members present at her public defense

Congratulations to Adélie Lannoy who presented her Ph.D. public defense about a Mla-Pqi chimeric complex and a two component system, both crucial for Brucella abortus virulence

31.01.2025 12:07 — 👍 7    🔁 4    💬 2    📌 0
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Role of a TonB-dependent receptor and an oxygenase in iron-dependent copper resistance in Caulobacter crescentus https://www.biorxiv.org/content/10.1101/2024.11.25.625226v1 Copper (Cu) is potentially threatening for living organisms owing to its toxicity at high concentrat

Role of a TonB-dependent receptor and an oxygenase in iron-dependent copper resistance in Caulobacter crescentus https://www.biorxiv.org/content/10.1101/2024.11.25.625226v1

26.11.2024 16:17 — 👍 4    🔁 3    💬 0    📌 1

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