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Mathieu Ferron

@mathieuferron.bsky.social

Mathieu Ferron Lab @ircm.bsky.social. Prof @umontreal.ca, Montreal, Québec. Vitamin K, bone, beta cell, ER stress and diabetes. Conseiller scientifique du CRCQ.🔬Québécois. https://www.ircm.qc.ca/en/researchers/mathieu-ferron

1,713 Followers  |  3,521 Following  |  262 Posts  |  Joined: 29.11.2024  |  2.0026

Latest posts by mathieuferron.bsky.social on Bluesky

Toutes nos félicitations à Xinying Zhang qui a soutenu sa thèse de doctorat intitulée «Fonctions divergentes des sous-groupes de neurones Phox2a de la voie antérolatérale spinale dans le traitement somatosensoriel» Bravo!! 👏
Elle était supervisée par le Dr Artur Kania, directeur de l'Unité de recherche en développement des circuits neuronaux.

Toutes nos félicitations à Xinying Zhang qui a soutenu sa thèse de doctorat intitulée «Fonctions divergentes des sous-groupes de neurones Phox2a de la voie antérolatérale spinale dans le traitement somatosensoriel» Bravo!! 👏 Elle était supervisée par le Dr Artur Kania, directeur de l'Unité de recherche en développement des circuits neuronaux.

Toutes nos félicitations à Xinying Zhang qui a soutenu sa thèse de doctorat intitulée «Fonctions divergentes des sous-groupes de neurones Phox2a de la voie antérolatérale spinale dans le traitement somatosensoriel» Bravo👏
Elle était supervisée par le Dr Artur Kania.

04.08.2025 10:43 — 👍 3    🔁 1    💬 0    📌 0
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The abstract vs the actual results.

26.07.2025 18:16 — 👍 9    🔁 2    💬 1    📌 0
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Today, I visited Minecraft Overworld...

22.07.2025 18:52 — 👍 1    🔁 0    💬 1    📌 0
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Even status are taking selfies au Musée du Louvre.

17.07.2025 19:22 — 👍 7    🔁 0    💬 0    📌 0
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I arrived in Paris this afternoon... A bit tire but enjoying some wine in my backyard. Yes, amazingly we found a place in the 16eme with a small back yard.

15.07.2025 17:56 — 👍 8    🔁 0    💬 0    📌 0

Ouh Ouh Ouh

12.07.2025 00:48 — 👍 1    🔁 0    💬 0    📌 0

Ça fait longtemps que j'avais écouté du Louise Attaque.

12.07.2025 00:09 — 👍 1    🔁 0    💬 1    📌 0

J'écoute Plastic Bertrand en faisant la vaisselle. You are the king of the divan...

11.07.2025 23:51 — 👍 4    🔁 0    💬 3    📌 0

I know, and they lure me to the coffee break area by telling me there was a problem with a microscope in the cell culture room.

11.07.2025 19:28 — 👍 2    🔁 0    💬 1    📌 0
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Update, the lab prepared cakes for my promotion!

11.07.2025 19:24 — 👍 7    🔁 0    💬 1    📌 0

Merci d'avoir organisé l'évènement. Je trouvais ça vraiment cool que les membres du labo soient invités!

11.07.2025 17:05 — 👍 1    🔁 0    💬 1    📌 0
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Most recent team picture. I am so lucky to work with those amazing scientists!

11.07.2025 02:10 — 👍 38    🔁 1    💬 2    📌 0
👏 The IRCM salutes Dr. Michel Cayouette's remarkable commitment to Fighting Blindness Canada (VCC).
For over 10 years, Dr. Cayouette, Vice-President of Research and Academic Affairs at the IRCM, has been involved with VCC's Board of Directors and chairs its Scientific Advisory Committee.
🔬 As head of the IRCM's Cellular Neurobiology Research Unit and the FRQS Vision Sciences Research Network, Dr. Cayouette and his teams conduct cutting-edge research in visual health that advances knowledge of eye diseases and paves the way for new therapies.
Congratulations and thank you for this exceptional commitment to research!

👏 The IRCM salutes Dr. Michel Cayouette's remarkable commitment to Fighting Blindness Canada (VCC). For over 10 years, Dr. Cayouette, Vice-President of Research and Academic Affairs at the IRCM, has been involved with VCC's Board of Directors and chairs its Scientific Advisory Committee. 🔬 As head of the IRCM's Cellular Neurobiology Research Unit and the FRQS Vision Sciences Research Network, Dr. Cayouette and his teams conduct cutting-edge research in visual health that advances knowledge of eye diseases and paves the way for new therapies. Congratulations and thank you for this exceptional commitment to research!

The IRCM salutes Dr. Michel Cayouette’s remarkable commitment to Fighting Blindness Canada (FBC). For over 10 years, he has served on FBC’s Board of Directors and chairs its Scientific Advisory Committee. Congratulations and thank you for this outstanding dedication to research!
bit.ly/4kqdMbp

07.07.2025 10:36 — 👍 9    🔁 1    💬 0    📌 0

Probably the same people who asked for a narrative CV?

07.07.2025 20:23 — 👍 0    🔁 0    💬 0    📌 0
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Molecular basis of vitamin-K-driven γ-carboxylation at the membrane interface - Nature Cryo-electron microscopy structures reveal the mechanisms underlying multiple-substrate specificity, coupling of epoxidation with carboxylation and allosteric motions during VKGC catalysis, offering p...

3) GGCX is a complex protein to fold (9 TM) and contains multiple glycosylation sites on its C-terminus which are required for its activity. It is unlikely that it could exist in a non-glycosylated version and still be active. See the recently published structure:

www.nature.com/articles/s41...

04.07.2025 19:06 — 👍 3    🔁 0    💬 0    📌 0

2) VK reduction occurs on the luminal side of the ER membrane, so it is really hard to understand how this flipped GGCX will be able to access its cofactor from the cytosolic site.

04.07.2025 19:06 — 👍 1    🔁 0    💬 1    📌 0

My lab works on GGCX and VK, and I was very surprised when I read that paper. There are several issues with the proposed model: 1) We never detected carboxylated protein in the cytosol in any of our proteomic screens.

04.07.2025 19:06 — 👍 6    🔁 2    💬 2    📌 0

📣 We are looking for a full-time research technician. This is a great opportunity for recent grads seeking additional hands-on experience before grad or med school. Join our team in exploring GPCR signaling and pharmacology at @dukemedschool.bsky.social Description: careers.duke.edu/job/Durham-R...

02.07.2025 13:58 — 👍 3    🔁 3    💬 0    📌 1
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Brittle, but not boring: a fresh look at osteogenesis imperfecta type V Bone tissue homeostasis relies on a strict balance between bone resorption by osteoclasts and bone formation by osteoblasts. Studies of animal models with

I wrote this editorial with my former PhD advisor Dr Jean Vacher! (sorry I forgot to post it before)

Brittle, but not boring: a fresh look at osteogenesis imperfecta type V url: academic.oup.com/jbmr/article...

29.06.2025 21:25 — 👍 2    🔁 0    💬 0    📌 0

Oui effectivement.

27.06.2025 17:34 — 👍 0    🔁 0    💬 0    📌 0

Julien Poulin dans le rôle de James Gratton.

27.06.2025 12:58 — 👍 1    🔁 0    💬 1    📌 0
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One burning question is who will be the next James Bond? How about Pedro Pascal?

27.06.2025 00:40 — 👍 2    🔁 0    💬 1    📌 0
For scientists, the challenge of bringing science from the lab to the patient's bedside is enormous. The Office of Research Transfer supports discoveries so they become innovative therapies.
After completing a thesis in molecular biology, Sarah Nahlé chose to focus on research transfer. For the past month and a half, she has been completing a stimulating internship at the IRCM's Office of Research Promotion.
🔬 "[…] supporting researchers in the promotion of their discoveries is something I'm extremely interested in."
Her goal? To bridge the gap between science and industry to transform advances into concrete solutions for patients. A mission that is a core priority for the IRCM.
👏 Congratulations, Sarah, on this promising career path!

For scientists, the challenge of bringing science from the lab to the patient's bedside is enormous. The Office of Research Transfer supports discoveries so they become innovative therapies. After completing a thesis in molecular biology, Sarah Nahlé chose to focus on research transfer. For the past month and a half, she has been completing a stimulating internship at the IRCM's Office of Research Promotion. 🔬 "[…] supporting researchers in the promotion of their discoveries is something I'm extremely interested in." Her goal? To bridge the gap between science and industry to transform advances into concrete solutions for patients. A mission that is a core priority for the IRCM. 👏 Congratulations, Sarah, on this promising career path!

The Office of Research Transfer supports discoveries so they can become innovative therapies.
After completing a thesis in molecular biology, Sarah Nahlé chose to focus on research transfer.
👏 Congratulations, Sarah, on this promising career path!
bit.ly/4lpQy6c

26.06.2025 15:06 — 👍 3    🔁 1    💬 0    📌 0
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Serge Fiori est décédé à l’âge de 73 ans Le chanteur était le leader du groupe légendaire Harmonium.

Je l'imagine en train jammer avec Jésus et son band d'anges...

"J'ai perdu mon temps à gagner du temps"

ici.radio-canada.ca/nouvelle/217...

24.06.2025 18:40 — 👍 3    🔁 0    💬 0    📌 0
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a warehouse filled with lots of boxes and a person walking through it ALT: a warehouse filled with lots of boxes and a person walking through it

I see this:

24.06.2025 16:17 — 👍 1    🔁 0    💬 1    📌 0
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"A potent heat dome is building over the US, sending temperatures into the TRIPLE DIGITS!!!"

This headline makes no sense to anyone, except Americans.

#metricsystem

23.06.2025 17:42 — 👍 1    🔁 0    💬 0    📌 0

I was 14 months backlog... I spend two evenings doing it. The worst was to remember all the these committees I did in the last year.

22.06.2025 21:36 — 👍 1    🔁 0    💬 0    📌 0

Principal investigator: the only job for which you constantly need to update your CV even though you already have a job.

22.06.2025 20:52 — 👍 9    🔁 0    💬 1    📌 1
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Vitamin K: Metabolism, Genetic Influences, and Chronic Disease Outcomes Vitamin K exists in two natural isoforms: phylloquinone (PK, vitamin K1) and menaquinones (MKs, vitamin K2), and is an essential cofactor for the post-translational carboxylation of vitamin K-depende...

Nice review on vitamin K metabolism and link with diseases by Marc Sim and colleagues.

onlinelibrary.wiley.com/doi/10.1002/...

21.06.2025 18:12 — 👍 3    🔁 1    💬 0    📌 0
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I found those photos of my great-grandparents. They were not rich and lived on a rocky land in St-Eleuthere, QC.

21.06.2025 03:17 — 👍 3    🔁 0    💬 1    📌 0

@mathieuferron is following 20 prominent accounts