Julien Béthune

Nothing to see in flow through is also not typical….but also probably easy to fix with the right prompt

Welcome address for the EMMaH graduate ceremony

Introducing slide for the partner universities

The degree documents on a table

The first Erasmus Mundus graduates of the EMMaH masters with robes, hats and degrees

Yesterday we celebrated the graduation of the first Erasmus Mundus cohort of our international master program EMMaH - Euro-Asian Master of Medical Technology and Healthcare Business in Lille.
Congratulations to all our new graduates and good luck for your future endeavors!

Alleinerziehend in der Wissenschaft: Was Dauerstellen nicht lösen Ein Kommentar, angeregt von "Ziel erkannt, Ziel verfehlt?" von Amrei Bahr und Kristin Eichhorn

"Wer wird eingeladen? Wen sehen wir als „sichtbar“ und „erfolgreich“? Und wessen Leistungen übersehen wir systematisch, weil sie mehr Zeit brauchten, um dorthin zu kommen?"Tolle Reflexion @mariehuber.bsky.social zu Karriere und Kindern in der Wissenschaft seriousjourneys.substack.com/p/alleinerzi...

It’s clear we need alternatives or at least ways to improve the situation. So, together with a really special and talented team we worked to develop this idea into “qed” a platform where you can get CONSTRUCTIVE feedback on your own work or CRITICALLY assess other people’s papers.

AfD hetzt gegen Hochschulen: Angriff auf die Freiheit der Wissenschaft Die AfD Sachsen-Anhalt fragt gezielt nach Listen postkolonialer Seminare und Lehrstühle. Wie die Universitäten beginnen, sich gegen die Angriffe zu wappnen.

Die AfD Sachsen-Anhalt fragt gezielt nach Listen postkolonialer Seminare und Lehrstühle. Wie die Universitäten beginnen, sich gegen die Angriffe zu wappnen.

Multimodal AI agents for capturing and sharing laboratory practice We present a multimodal AI laboratory agent that captures and shares tacit experimental practice by linking written instructions with hands-on laboratory work through the analysis of video, speech, an...

In labs, hands-on expertise is often lost because it's not written down. We leverage multimodal AI agents to capture & share expertise by analyzing video and speech to generate protocols, detect errors, and guide researchers. #AI #TeamMassSpec
📄 Preprint: doi.org/10.1101/2025... 1/🧵

On the left - western blot of B16F10 cells wt and KO for CDK8. Our in house produced antibodies give a lot of unspecific bands. On the right same probes with antibodies preincubated with fixed CDK8 KO cells - there is a specific band and faint unspecific bands, which can be probably eliminated with increase of amount of KO cells.

Neat trick if you polycolonal ab's suck. Incubate them with fixed cells with a KO of your protein of interest, then spin. Protocol here: www.med.upenn.edu/markslab/ass...
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky

Benchmarking of proximity-dependent biotinylation enzymes across cellular compartments and time windows Proximity-dependent biotinylation has become a powerful approach for mapping protein interactions and subcellular organization in living cells. Although a growing number of engineered biotin ligases h...

www.biorxiv.org/content/10.1...
For anybody doing proximity-dependent biotinylation have a look at this reference preprint from the @gingraslab.bsky.social . Ten enzymes benchmarked in various conditions, it appears #ultraID is the enzyme of choice for combined specificity, speed and low background🧪

Oh man, Hamburg has so much to offer than Currywurst!

Black and white portrait of a young man in a shirt, looking directly at the camera with a slight smile.

An elderly person with glasses and a cap smiling inside a busy bus.

12 September 1924 | A Hungarian Jew, Tibor "Ted” Bolgar, was born in Sárospatak.

In June 1944, he was deported to #Auschwitz from where he was taken to other camps. He was liberated during a death march from Muhldorf.

Today he turns 101. Join us in wishing him a happy birthday.

Academic authors, here's a peek into the black box of journal publishing from an journal editor if you can bear it:

Well that's amazing.

Mr Béthune in front of the city hall of Béthune

The city hall of Béthune

View of Béthune’s belfry and church tower

Some historic houses in Béthune

First time in the fair city of Béthune since 1991, glad to be back in the town that bears my name and recommended visit if visiting north of France!

Spent quite some time earlier this year to find Saturn with my old small telescope. Wanted to show my kids how cool the rings look. Was quite proud to find in spite of challenging background luminosity and then discovered that the rings are hardly visible this year….😔

The mechanistic basis of cargo selection during Golgi maturation The multiple cisternae of the Golgi apparatus contain resident membrane proteins crucial for lipid and protein glycosylation. How Golgi residents remain in their designated compartments despite a cons...

This is cool. CryoEM showing COPI coat containing GOLPH3, together with functional data suggests the mechanism for cargo retention/transport.

The mechanistic basis of cargo selection during Golgi maturation

Taylor, Zubkov, Ciazynska et al.

doi.org/10.1101/2025...

Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...

There are now 24 step-by-step guides, explaining how to create these ⬇️ data visualizations with R/ggplot2 - I hope this is a useful resource. Find them all here: joachimgoedhart.github.io/DataViz-prot...

🧪 this one is a nice one for anybody interested in the early secretory pathway!

Scientific bedlam at the world’s weirdest and wildest research conference Woodstock Bio2 + Night Science aimed to encourage collaborations through creativity. The walk-on music for presentations was fun, too.

www.nature.com/articles/d41...

Imidazole propionate is a driver and therapeutic target in atherosclerosis - Nature Imidazole propionate produced by gut microbiota is associated with atherosclerosis in mouse models and in humans, and causes the development of atherosclerosis through activation of the imidazoline-1 ...

💥 A gut microbe metabolite that drives #atherosclerosis?
Yes—Imidazole propionate (ImP) triggers vascular inflammation without changing cholesterol.
🧪 We show the pathway—and how to block it.
nature.com/articles/s41... #OpenAccess at
@Nature
@CNIC_CARDIO
#CVD #immunosky #cardiosky #microbiomesky

Are bar plots without error bars or individual data really the future?
While I agree on many things said here, I don't think that the chosen examples of bar plots are a good way forward

Carlos Santana playing the guitar

The magician in Hamburg earlier this week

Program now available for 3rd INTERNATIONAL TOP-DOWN PROTEOMICS SYMPOSIUM in Hamburg, Germany August 26-28 and DEADLINES approaching:

>Early Registration ends - JUNE 30
>For Oral Abstract Submissions – JUNE 30
>For Poster Abstract Submissions – JULY 15

Get the Program here >> publ.cc/UFWQwg

CrossFilt: A Cross-species Filtering Tool that Eliminates Alignment Bias in Comparative Genomics Studies Comparative functional genomic studies are often affected by biased read mapping across species due to inter-species differences in genome structure, sequence composition, and annotation quality. We d...

We developed CrossFilt, a read-level, cross-species filtering approach that avoids these errors without sacrificing usable data. It outperforms all existing strategies and exposes just how much signal in comparative genomics has been misread.

doi.org/10.1101/2025...

7. Oktober und Gaza-Krieg: Humanität ist unteilbar! In den vergangenen Monaten hat es in und rund um unseren Verein zahlreiche Debatten über den Nahost-Konflikt gegeben. Dazu möchte der FC St. Pauli einige grundlegende Gedanken teilen und einige falsch...

7. Oktober und Gaza-Krieg: Humanität ist unteilbar!

#fcsp

HAW Hamburg Students show their poster to Hamburg’ senator for research

Biotechnology and science communication at its best: Ad-hoc-Präsentation unserer HAW Hamburg Studierenden über ihr Forschungsprojekt vor Maryam Blumenthal, Senatorin für Wissenschaft, Forschung und Gleichstellung 💪🧪💪

To be honest this is to be compared to the 16 billions that are already there in the ERC program. So much more money was and is still there for all the researchers who are already here or want to come here.

a black background with flowers and the words `` once upon a time '' ALT: a black background with flowers and the words `` once upon a time ''

D'où viennent les mythes ? Les versions changent avec le temps en suivant des lois darwiniennes, raison pour laquelle il est possible de remonter à leurs origines, en construisant des arbres phylogénétiques. Cela fait 10 ans que les chercheurs construisent de tels arbres. Comment font-ils ? 👇

I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs.

Plant, Bacterial, Archaeal Non-model Bioeng
Custom Lab Hardware
Turn Key Genetic Design

Please repost for reach 💚