@mablelam-phd.bsky.social
NINDS K99 Fellow in the Zuchero lab @ Stanford | myelin cell biology | Former Helen Hay Whitney | PhD in the Walter lab @UCSF | she/her
🎉 Huge congrats to my advisor @bradzuchero.bsky.social and @ethanhugheslab.bsky.social for this McKnight award!
med.stanford.edu/neurosurgery...
We had fun assembling images and describing approaches for imaging oligodendrocytes and myelin in vivo, in organotypic slices, and in fixed tissues. This work started in the lab of @jgrutzendler.bsky.social over 10 years ago and continues to keep us busy.
www.nature.com/articles/s44...
Was a lot of fun working on this piece with Ben Clayton for @annualreviews.bsky.social
Reactive astrocyte heterogeneity is a thoroughly exciting and complicated problem... lots of exciting discoveries in recent years.
www.annualreviews.org/content/jour...
Image reads: since President Trump has taken office, HHS has cut over $9.5 billion in grant funding that had been approved but not yet distributed to programs and researchers
The NYT is doing a great job on these infographics showing how taxpayer money is being blocked from reaching its intended recipients
www.nytimes.com/interactive/...
The cover of the book, in greenish blueish color. The title is "The autobiography of a transgender scientist" by one of the most badass human beings that have ever existed, Ben Barres
TIL that one of the books removed from the Armed Forces Library because it "had DEI" in it is Ben Barres' autobiography. Remember that you can buy and should read this book because Ben was badass and an amazing scientist mitpress.mit.edu/978026253954...
27.06.2025 08:55 — 👍 150 🔁 41 💬 3 📌 1Being part of the myelin field has been the most rewarding aspect of my scientific career ❤️
23.06.2025 18:51 — 👍 23 🔁 6 💬 0 📌 0
A graphic with horizontal red, black, and green stripes—colors of the Pan-African flag. In the center is a cream-colored circular outline featuring the profile of a Black woman wearing a geometric-patterned headwrap and large hoop earring. Arched above the circle is the word “JUNETEENTH” and below it reads “FREEDOM DAY” in curved, playful cream text. The Black In Neuro logo appears in the bottom left corner.
A graphic with horizontal blocks of red, black, and green — colors of the Pan-African flag — features a cream-colored box in the center. At the top, bold red text reads “DID YOU KNOW.” Inside the box, brown text states: “Juneteenth commemorates June 19, 1865, the day enslaved people in Galveston, Texas were finally informed of their freedom—over two years after the Emancipation Proclamation was signed.” Below a row of green dots, it continues: “It marks the end of slavery in the US and an important celebration of Black freedom, resilience, and joy.” In the bottom left corner is the Black In Neuro logo.
A graphic with a red, black, and green striped background features a centered cream-colored box. At the top, bold red text reads: “THE FIGHT IS NOT OVER.” Inside the box, brown text states: “Juneteenth reminds us that freedom is not truly granted until it is realized by all. As we reflect on the delayed liberation of enslaved people in 1865, we’re called to continue the fight for justice, equality, and liberation—everywhere. This history teaches us that no one is free until everyone is free.” In the bottom left corner is the Black In Neuro logo.
🖤 On #Juneteenth, we honor the fight for Black freedom — delayed, but never denied.
At #BlackInNeuro, we carry that legacy forward by creating space for Black excellence in neuroscience, year-round. ✨
Freedom is a journey — and we’re not done yet. ✊🏾
Cholinergic neuronal activity promotes diffuse midline glioma growth through muscarinic signaling: Cell www.cell.com/cell/fulltex...
20.06.2025 02:03 — 👍 46 🔁 15 💬 0 📌 0
Our latest work:
The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis: Cell www.cell.com/cell/fulltex...
Myelin–axon interface vulnerability in Alzheimer’s disease revealed by subcellular proteomics and imaging of human and mouse brain
www.nature.com/articles/s41...
New paper from the lab officially out! Congratulations @marisosa.bsky.social - amazing work - and just before she sets off to UC Boulder to start her own lab!
11.06.2025 21:51 — 👍 30 🔁 4 💬 0 📌 0
🧪
#publichealth
#BethesdaDeclaration
Bravo to the courageous NIH scientists who put the Bethesda Declaration together. Non-NIH researchers are also encouraged to sign in support (see bottom of landing page).
www.standupforscience.net/bethesda-dec...
Emotions are core to the human experience 😆😮🙂😊☹️😠😳😑
But how do they arise? Our brain-wide ⚡recordings in humans and mice reveal some answers @ScienceMagazine. A big team effort and debut paper from @Stanford's new Human Neural Circuitry program. bit.ly/4dEyX7Z
Honored to be a part of this fantastic community! 🎉
27.05.2025 22:57 — 👍 4 🔁 0 💬 0 📌 0Let’s get the word out about the importance of federal funding of curiosity -driven science
We all have similar stories to share
Huge congrats (again 😊)!! 🎉
02.05.2025 16:53 — 👍 1 🔁 0 💬 1 📌 0
Shane Liddelow @liddelowsa.bsky.social shares how a game-changing cell culture method developed in Ben Barres’ lab transformed astrocyte studies and helped him build a career studying their reactive substates, in our latest “This paper changed my life.
www.thetransmitter.org/this-paper-c...
Excited to share this new work led by the talented Mike Dolan @dolan in collaboration with Evan macosko
See below for details and preprint
Congrats! So happy for you and hope the sleep continues 🤞🤞🤞
28.04.2025 16:45 — 👍 1 🔁 0 💬 1 📌 0Exciting news!! I’m joining the tenure-track faculty at University of Colorado Boulder this fall as an Assistant Professor of Psychology & Neuroscience!
The Sosa Lab will study how memory is shaped by cognitive and physiological demands, including during pregnancy and the postpartum period. 🧵
Microglia & monocyte-derived cells were long assumed to have similar functions during remyelination. Our new paper @plosbiology.org shows non-redundant roles, with monocytes ultimately inhibiting remyelination. Team effort by Bianca Hill,Rebecca Holloway, Lindsey Forbes,Claire Davies
plos.io/3RryCLF
Explore the newly launched Early-Career Neuroscientists Resource Center, designed to help you navigate the field with news, expert insights and practical tools. The page also highlights job openings, seminars, and more:
#neuroskyence
www.thetransmitter.org/early-career...
Super cool. Apoe impact on cell specific landscape in AD.
E2 enriched for oligodendrocyte and synaptic genes.
www.cell.com/neuron/abstr...
