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@lyons-lab.bsky.social

474 Followers  |  489 Following  |  9 Posts  |  Joined: 29.11.2024  |  1.7219

Latest posts by lyons-lab.bsky.social on Bluesky

Prof Khakh quote - I hope to make a meaningful difference to the lives of people affected by dementia by advancing new therapeutic mechanisms grounded in fundamental neuroscience, and by helping to build a research environment where great science and great scientists can thrive.

Prof Khakh quote - I hope to make a meaningful difference to the lives of people affected by dementia by advancing new therapeutic mechanisms grounded in fundamental neuroscience, and by helping to build a research environment where great science and great scientists can thrive.

Very excited to share the news today that Professor Baljit Khakh will become the new Centre Director of the UK DRI at Cardiff University!

Read our full announcement πŸ‘‰ www.ukdri.ac.uk/news-and-eve...

24.11.2025 13:26 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Led by Marcus Keatinge
"Mislocalisation of TDP-43 to the cytoplasm of either neurons or oligodendrocytes causes axonopathy and dysmyelination"

www.biorxiv.org/content/10.1...

18.11.2025 20:07 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
A man in a lab coat stands in a laboratory witht he background lab lit up in purple and blue

A man in a lab coat stands in a laboratory witht he background lab lit up in purple and blue

Β£70 million investment in IRR spinout Trogenix to tackle aggressive cancers.
The funding will enable the rapid advancement of its pipeline of potentially curative cancer therapies across multiple treatment-resistant cancers
regeneration-repair.ed.ac.uk/ps70-million...
@edinnovations.bsky.social

06.10.2025 13:00 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
FBXW7 regulates MYRF levels to control myelin capacity and homeostasis in the adult central nervous system - Nature Communications The homeostasis of myelin in the central nervous system is highly regulated, but the underlying mechanisms are unclear. Here, the authors show that the FBXW7 protein has a role in constraining myelin ...

www.nature.com/articles/s41...

21.08.2025 21:10 β€” πŸ‘ 4    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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Brilliant Kick off day #ISNASN2025
@neurochemistry.org with the best conference views ever 😎
Glad to be part of it #TogetherForScience

If you wanna know more about my work on axons & zebrafish in the @lyons-lab.bsky.social join me during the poster session tmr evening (LBA45) or just reach out 🐠

19.08.2025 20:55 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Activity-driven myelin sheath growth is mediated by mGluR5 - Nature Neuroscience Employing pharmacology, genetics and all-optical approaches in zebrafish, Braaker et al. find that neuronal activity influences the growth of myelin sheaths along axons by signaling through metabotrop...

For those who want a distraction and/ or are interested, here's the latest from the group, led by Phil Braaker

www.nature.com/articles/s41...

14.05.2025 11:45 β€” πŸ‘ 48    πŸ” 22    πŸ’¬ 1    πŸ“Œ 4
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The LSI Exeter invites you to join the first UK Zebrafish Meeting, 10/ - 12/9/ @lsiexeter.bsky.social. We are looking for motivated PhD students/ECRs to present their work - as talks and posters. www.exeter.ac.uk/research/ins... . The deadline for the early bird registration is 15/5/. So, be quick!

14.04.2025 12:03 β€” πŸ‘ 13    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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Fast, accurate, and versatile data analysis platform for the quantification of molecular spatiotemporal signals Optical recording of intricate molecular dynamics is becoming an indispensable technique for biological studies, accelerated by the development of new…

Fun to have contributed a little to this, led by the team of the incomparable Guoqiang Yu.

Suspect that this will prove to be an immensely popular image analysis platform for interrogation of dynamic signallingl!
www.sciencedirect.com/science/arti...

08.04.2025 15:59 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Hot damn!
Spectacular news Karl. Massive congrats Michelle!@michellemonje.bsky.social

06.03.2025 08:28 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Defining the molecular identity and morphology of glia limitans superficialis astrocytes in vertebrates Hasel etΒ al. show that molecularly and morphologically specialized astrocytes make up the brain and spinal cord surface, thereby creating the glia limitans superficialis. These astrocytes selectively ...

Our paper on the superficial glia limitans is now published - huge thank you to all co-authors that helped getting this work across the finish line! www.cell.com/cell-reports...

24.02.2025 10:44 β€” πŸ‘ 40    πŸ” 17    πŸ’¬ 1    πŸ“Œ 0

Two new opportunities in Edinburgh:

Research technician in our lab
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

Senior research technician to support the Zebrafish Imaging and Screening Facility
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

24.02.2025 11:20 β€” πŸ‘ 5    πŸ” 3    πŸ’¬ 0    πŸ“Œ 2

One week to go before application deadlines...

1. Postdoc, investigating how neurons respond to demyelination.
2. Research assistant, investigating how conduction properties are established in neural circuits

elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

27.01.2025 08:21 β€” πŸ‘ 12    πŸ” 12    πŸ’¬ 1    πŸ“Œ 0

Couple of opportunities up to join the group!
One at postdoc level, but open to senior support path.
One research assistant role.
Please share, or drop a line if you want to learn more!
Or just apply!
Thanks!

elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

16.01.2025 18:41 β€” πŸ‘ 14    πŸ” 20    πŸ’¬ 0    πŸ“Œ 1
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Developmental axon diameter growth of central nervous system axons does not depend on ensheathment or myelination by oligodendrocytes Myelination facilitates the rapid conduction of action potentials along axons. In the central nervous system (CNS), myelinated axons vary over 100-fold in diameter, with conduction speed scaling linea...

First post at this side.

Latest axon diameter action led by Jenea Bin, in collaboration with Nolan, Mobius, Monk, Werner, and Emery labs.

www.biorxiv.org/content/10.1...

11.01.2025 17:24 β€” πŸ‘ 28    πŸ” 14    πŸ’¬ 2    πŸ“Œ 2

@lyons-lab is following 20 prominent accounts