#Parasitology
#Malaria parasite invasion damages mosquito salivary glands, alters saliva protein composition, and attracts immune cells, potentially increasing parasite transmission
@jvr-lab.bsky.social
http://dlvr.it/TQTlT1
#Parasitology
#Malaria parasite invasion damages mosquito salivary glands, alters saliva protein composition, and attracts immune cells, potentially increasing parasite transmission
@jvr-lab.bsky.social
http://dlvr.it/TQTlT1
#Parasitology
#Malaria parasite invasion damages mosquito salivary glands, alters saliva protein composition, and attracts immune cells, potentially increasing parasite transmission
@jvr-lab.bsky.social
http://dlvr.it/TQNwSG
Postdoc opportunity ALERT!
Interested in exploring interactions between #wolbachia , #anopheles mosquitoes and #microbiome? check this postdoc position in Dr. Grant Hughes lab at Liverpool School of Tropical Medicine @mosquitomicrobe.bsky.social
app.vacancy-filler.co.uk/salescrm/Car...
Enjoying a beer with my friend Gabi in a beautiful Aachen afternoon. It was great to see you. Thank you for the invitation and the great time.
👩🏼🔬🧑🏽🔬 🦠 🦟 🔬 🧬
@gabrielepradel.bsky.social
Exited to deliver the keynote address together with Markus Ganter at the @spp2225.bsky.social EXIT Workshop in beautiful Aachen, Germany. Thank you @gabrielepradel.bsky.social for the invitation and hospitality. 👨🏽🔬 🦟 🦠 🩸🔬
@rwth.bsky.social @dfg.de @niaidnews.bsky.social
🚨 New preprint alert! 🚨
We’ve uncovered a key player in malaria parasite cell division—meet PfAnchor, the first apicoplast-specific dynamin adaptor protein! Check the thread below 🧵for more details. #U_ExM #Malaria #Apicoplast
www.biorxiv.org/content/10.1...
Pre-print Alert! We uncover new sporozoite biology in mosquitoes, classified sporogony stages in oocysts and showed that sporozoites produce 2 rhoptry pairs, each one specialized for salivary gland and hepatocyte invasion. @benliffner.bsky.social @sabsalon.bsky.social @thiagoluizsilva.bsky.social
12.04.2025 13:18 — 👍 10 🔁 3 💬 1 📌 0
📢 @lstmnews.bsky.social : "Drug used for rare genetic disorders kills #mosquitoes capable of #malaria transmission" 🦟
www.lstmed.ac.uk/news-events/...
Congratulations!🥂🍾✨
27.03.2025 12:38 — 👍 1 🔁 0 💬 0 📌 0
Look at those beautiful #mosquito midguts infected with #malaria parasites.
Congratulations @sabsalon.bsky.social and @benliffner.bsky.social
Congratulations @benliffner.bsky.social. #U_ExM #Malaria revolutionized studying the cell biology of Apicomplexan parasites, and I love the work we did together ;-)
19.03.2025 13:42 — 👍 27 🔁 2 💬 1 📌 1Congratulations!🥂🍾✨
19.03.2025 23:55 — 👍 1 🔁 0 💬 0 📌 0This is so cool! 🚀 🧑🚀 🐬
19.03.2025 01:28 — 👍 1 🔁 0 💬 0 📌 0
Part of the Special Issue on Vectors and medical and veterinary entomology (2025). Editor @joshuabenoit.bsky.social
Great job @thiagoluizsilva.bsky.social and @renukajoseph.bsky.social
www.sciencedirect.com/special-issu...
Mosquito responses to modulate the host's blood humoral and cellular responses in the mosquito midgut. After blood ingestion, the human hemostatic and immune responses in the blood bolus remain active. Mosquitoes employ both early and late strategies to counter these host responses and protect the midgut epithelium: 1. Early responses – Mosquito ingests saliva containing bioactive proteins, such as apyrase and AAPP, that inhibit platelet aggregation, NETosis, and other host hemostatic and immune activities. 2. Late responses - The formation of the peritrophic matrix shields the midgut epithelium from microbes, free heme, and other toxic blood components. Additionally, the ingested blood stimulates gene expression, activating pathways for nutrient uptake, metabolic adaptation, and immune defense.
New review alert-Mosquito saliva does more than just help them feed—it also influences blood responses in the midgut, enhancing Plasmodium transmission. Could targeting saliva proteins be the key to blocking disease spread? #Malaria #Mosquito #VectorControl
www.sciencedirect.com/science/arti...
Our 2025 March issue bit.ly/2N9R8Es reviews blood impact on vector-borne diseases, zoonotic Giardia transmission in cattle, parasite subcellular dynamics, Bacillus thuringiensis for nematode management, heptalaminate membrane of intravascular schistosomes, trade-offs in virulence evolution, & more
06.03.2025 12:27 — 👍 16 🔁 8 💬 4 📌 2Fantastic collaboration with @sachiekanatani.bsky.social @freddyfrischknecht.bsky.social and the Sinnis, Barillas-Mury, Ribeiro, and Coppens labs.
03.03.2025 15:13 — 👍 0 🔁 0 💬 0 📌 0
New Pre-print from our lab
High-Resolution Proteomics Unveils Salivary Gland Disruption and Saliva-Hemolymph Protein Exchange in Plasmodium-Infected Mosquitoes
Led by @thiagoluizsilva.bsky.social
🦟 🦟🦟🦟🦟🦟🦟🦟🦟🦟🦟
#mosquito #malaria #proteomics #infectiousdiseases
www.biorxiv.org/content/10.1...
Glad to hear that my friend!
25.02.2025 02:25 — 👍 1 🔁 0 💬 0 📌 0
New paper published with the Benoit lab at the University of Cincinnati!
www.sciencedirect.com/science/arti...
Check out our paper, co-authored by @akhorramnejad.bsky.social and me. Published in @commsbio.bsky.social
We explore how global change will affect mosquito-virus interaction. We use single or multi-generational exposure to heat to address this.
A 🧵 with our results (1/5)
rdcu.be/d8wse
Congratulations Hugo and the team! Beautiful study! 🥂🍾✨
04.02.2025 22:49 — 👍 0 🔁 0 💬 1 📌 0
New preprint from the lab in which we show that Trichoderma culture supernatant kills Aedes albopictus larvae 🦟🍄 www.biorxiv.org/content/10.1...
22.01.2025 12:28 — 👍 9 🔁 5 💬 0 📌 0
Our article on #mosquito salivary apyrase featured at The Scientist Thanks Mary Ann McDowell for the insightful comments! “Targeting Mosquito Spit Could Stop Parasites in Their Tracks”
www.the-scientist.com/targeting-mo...
Our paper on the role of #mosquito salivary apyrase in regulating blood meal #hemostasis and #malaria #parasite transmission. Apyrase #immunization inhibits both transmissions.
www.nature.com/articles/s41...
Our paper on U-ExM for mosquito tissues (MoTissU-ExM) in BMC methods!
Great collaboration with @sabsalon.bsky.social and @benliffner.bsky.social
bmcmethods.biomedcentral.com/articles/10....
